Regulation of dendritic spine morphogenesis by insulin receptor substrate 53, a downstream effector of Rac1 and Cdc42 small GTPases
about
The RAC binding domain/IRSp53-MIM homology domain of IRSp53 induces RAC-dependent membrane deformationDGKι regulates presynaptic release during mGluR-dependent LTDRegulation of IRSp53-dependent filopodial dynamics by antagonism between 14-3-3 binding and SH3-mediated localization.Kank attenuates actin remodeling by preventing interaction between IRSp53 and Rac1Actin in dendritic spines: connecting dynamics to functionEmerging Roles of BAI Adhesion-GPCRs in Synapse Development and PlasticityInsulin in the brain: there and back againThe BAI subfamily of adhesion GPCRs: synaptic regulation and beyondInsulin in the brain: its pathophysiological implications for States related with central insulin resistance, type 2 diabetes and Alzheimer's diseaseUltrastructural abnormalities in CA1 hippocampus caused by deletion of the actin regulator WAVE-1Mechanism of IRSp53 inhibition and combinatorial activation by Cdc42 and downstream effectorsHippocampal CA3 transcriptome signature correlates with initial precipitating injury in refractory mesial temporal lobe epilepsyRegulation of cell shape by Cdc42 is mediated by the synergic actin-bundling activity of the Eps8-IRSp53 complexThe insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticityThe adhesion-GPCR BAI1 regulates synaptogenesis by controlling the recruitment of the Par3/Tiam1 polarity complex to synaptic sites.Dysbindin-1, WAVE2 and Abi-1 form a complex that regulates dendritic spine formationSPIN90/WISH interacts with PSD-95 and regulates dendritic spinogenesis via an N-WASP-independent mechanismPostsynaptic distribution of IRSp53 in spiny excitatory and inhibitory neuronsThe neuronal proteins CIPP, Cypin and IRSp53 form a tripartite complex mediated by PDZ and SH3 domains.Espins and the actin cytoskeleton of hair cell stereocilia and sensory cell microvilli.Expression profiling reveals differential gene induction underlying specific and non-specific memory for pheromones in mice.Molecular architecture of synaptic actin cytoskeleton in hippocampal neurons reveals a mechanism of dendritic spine morphogenesis.Membrane targeting of WAVE2 is not sufficient for WAVE2-dependent actin polymerization: a role for IRSp53 in mediating the interaction between Rac and WAVE2.SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties.Optimization of WAVE2 complex-induced actin polymerization by membrane-bound IRSp53, PIP(3), and Rac.Mice lacking the synaptic adhesion molecule Neph2/Kirrel3 display moderate hyperactivity and defective novel object preferenceLhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of EspinDevelopmental expression and differentiation-related neuron-specific splicing of metastasis suppressor 1 (Mtss1) in normal and transformed cerebellar cells.Severe learning deficits of IRSp53 mutant mice are caused by altered NMDA receptor dependent signal transduction.Integrative Analysis of Brain Region-specific Shank3 Interactomes for Understanding the Heterogeneity of Neuronal Pathophysiology Related to SHANK3 Mutations.SPIN90 phosphorylation modulates spine structure and synaptic functionInsulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo.MAGUKs, synaptic development, and synaptic plasticityThe role of actin bundling proteins in the assembly of filopodia in epithelial cellsModulation of hippocampal neural plasticity by glucose-related signaling.WRP/srGAP3 facilitates the initiation of spine development by an inverse F-BAR domain, and its loss impairs long-term memory.Organizational actions of metabolic hormones.Rac GEF Dock4 interacts with cortactin to regulate dendritic spine formation.Proteomic analysis of postsynaptic density in Alzheimer's diseaseNeural palmitoyl-proteomics reveals dynamic synaptic palmitoylation.
P2860
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P248
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P2860
Regulation of dendritic spine morphogenesis by insulin receptor substrate 53, a downstream effector of Rac1 and Cdc42 small GTPases
description
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Januar 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/01/26)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/01/26)
@nl
наукова стаття, опублікована в січні 2005
@uk
مقالة علمية (نشرت في 26-1-2005)
@ar
name
Regulation of dendritic spine ...... f Rac1 and Cdc42 small GTPases
@ast
Regulation of dendritic spine ...... f Rac1 and Cdc42 small GTPases
@en
Regulation of dendritic spine ...... f Rac1 and Cdc42 small GTPases
@nl
type
label
Regulation of dendritic spine ...... f Rac1 and Cdc42 small GTPases
@ast
Regulation of dendritic spine ...... f Rac1 and Cdc42 small GTPases
@en
Regulation of dendritic spine ...... f Rac1 and Cdc42 small GTPases
@nl
prefLabel
Regulation of dendritic spine ...... f Rac1 and Cdc42 small GTPases
@ast
Regulation of dendritic spine ...... f Rac1 and Cdc42 small GTPases
@en
Regulation of dendritic spine ...... f Rac1 and Cdc42 small GTPases
@nl
P2093
P921
P1476
Regulation of dendritic spine ...... f Rac1 and Cdc42 small GTPases
@en
P2093
Alain Burette
Eunjoon Kim
Hyun Woo Lee
Jae-Ran Lee
Jeonghoon Choi
Moonseok Na
P304
P356
10.1523/JNEUROSCI.3212-04.2005
P407
P577
2005-01-26T00:00:00Z