Beta-adrenergic regulation requires direct anchoring of PKA to cardiac CaV1.2 channels via a leucine zipper interaction with A kinase-anchoring protein 15
about
Estrogen receptor beta-selective agonists stimulate calcium oscillations in human and mouse embryonic stem cell-derived neuronsMutation of an A-kinase-anchoring protein causes long-QT syndromePhosphorylation of the A-kinase-anchoring protein Yotiao contributes to protein kinase A regulation of a heart potassium channelCa(2+) signaling in the myocardium by (redox) regulation of PKA/CaMKIICaV1.2 signaling complexes in the heartIon channel remodeling in vascular smooth muscle during hypertension: Implications for novel therapeutic approachesRegulation of Cardiac Calcium Channels in the Fight-or-Flight ResponseVoltage-gated calcium channelsNetworking with AKAPs: context-dependent regulation of anchored enzymesPhosphodiesterase 4B in the cardiac L-type Ca²⁺ channel complex regulates Ca²⁺ current and protects against ventricular arrhythmias in miceApproaches and tools for modeling signaling pathways and calcium dynamics in neuronsAssembly of a Ca2+-dependent BK channel signaling complex by binding to beta2 adrenergic receptorIdentification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cellsAKAP79/150 anchoring of calcineurin controls neuronal L-type Ca2+ channel activity and nuclear signalingPhosphorylation of the cAMP-dependent protein kinase (PKA) regulatory subunit modulates PKA-AKAP interaction, substrate phosphorylation, and calcium signaling in cardiac cellsSmall molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytesDopamine modulation of neuronal Na(+) channels requires binding of A kinase-anchoring protein 15 and PKA by a modified leucine zipper motifLocalization of cardiac L-type Ca(2+) channels to a caveolar macromolecular signaling complex is required for beta(2)-adrenergic regulationGraded Ca2+/calmodulin-dependent coupling of voltage-gated CaV1.2 channelsProtein kinase A modulation of CaV1.4 calcium channelsModulation of CaV1.2 channels by Mg2+ acting at an EF-hand motif in the COOH-terminal domainDisruption of protein kinase A localization using a trans-activator of transcription (TAT)-conjugated A-kinase-anchoring peptide reduces cardiac function.Basal and β-adrenergic regulation of the cardiac calcium channel CaV1.2 requires phosphorylation of serine 1700Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression.Cardiac troponin T, a sarcomeric AKAP, tethers protein kinase A at the myofilaments.Stable membrane expression of postsynaptic CaV1.2 calcium channel clusters is independent of interactions with AKAP79/150 and PDZ proteins.The C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy.Autoregulation of cardiac l-type calcium channels.Sites of proteolytic processing and noncovalent association of the distal C-terminal domain of CaV1.1 channels in skeletal muscleModulation of calcium-dependent inactivation of L-type Ca2+ channels via β-adrenergic signaling in thalamocortical relay neuronsBeta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.Mapping the binding site of TRPV1 on AKAP79: implications for inflammatory hyperalgesia.Targeting protein-protein interactions within the cyclic AMP signaling system as a therapeutic strategy for cardiovascular disease.Deletion of the distal C terminus of CaV1.2 channels leads to loss of beta-adrenergic regulation and heart failure in vivo.Functional roles of a C-terminal signaling complex of CaV1 channels and A-kinase anchoring protein 15 in brain neurons.Targeting of protein phosphatases PP2A and PP2B to the C-terminus of the L-type calcium channel Ca v1.2.The role of incretins in glucose homeostasis and diabetes treatment.The PDZ motif of the α1C subunit is not required for surface trafficking and adrenergic modulation of CaV1.2 channel in the heart.Activation of the GLP-1 receptor signalling pathway: a relevant strategy to repair a deficient beta-cell massMechanisms of specificity in neuronal activity-regulated gene transcription
P2860
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P2860
Beta-adrenergic regulation requires direct anchoring of PKA to cardiac CaV1.2 channels via a leucine zipper interaction with A kinase-anchoring protein 15
description
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2003
@ast
im Oktober 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/10/28)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/10/28)
@nl
наукова стаття, опублікована в жовтні 2003
@uk
name
Beta-adrenergic regulation req ...... A kinase-anchoring protein 15
@ast
Beta-adrenergic regulation req ...... A kinase-anchoring protein 15
@en
Beta-adrenergic regulation req ...... A kinase-anchoring protein 15
@nl
type
label
Beta-adrenergic regulation req ...... A kinase-anchoring protein 15
@ast
Beta-adrenergic regulation req ...... A kinase-anchoring protein 15
@en
Beta-adrenergic regulation req ...... A kinase-anchoring protein 15
@nl
prefLabel
Beta-adrenergic regulation req ...... A kinase-anchoring protein 15
@ast
Beta-adrenergic regulation req ...... A kinase-anchoring protein 15
@en
Beta-adrenergic regulation req ...... A kinase-anchoring protein 15
@nl
P2093
P2860
P3181
P356
P1476
Beta-adrenergic regulation req ...... A kinase-anchoring protein 15
@en
P2093
Joanne T. Hulme
Ruth E. Westenbroek
Teddy W.-C. Lin
Todd Scheuer
William A. Catterall
P2860
P304
13093–13098
P3181
P356
10.1073/PNAS.2135335100
P407
P577
2003-10-28T00:00:00Z