MinK-related peptide 1: A beta subunit for the HCN ion channel subunit family enhances expression and speeds activation
about
KCNE1 and KCNE3 beta-subunits regulate membrane surface expression of Kv12.2 K(+) channels in vitro and form a tripartite complex in vivoDifferential association between HERG and KCNE1 or KCNE2The KCNE2 K+ channel regulatory subunit: Ubiquitous influence, complex pathobiologyKCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current.Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation.KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels.Hypoosmotic cell swelling as a novel mechanism for modulation of cloned HCN2 channels.KCNE4 is an inhibitory subunit to the KCNQ1 channelMechanisms underlying the cardiac pacemaker: the role of SK4 calcium-activated potassium channelsHyperpolarization-activated current, If, in mathematical models of rabbit sinoatrial node pacemaker cellsGenetic evidence in the mouse solidifies the calcium hypothesis of myofiber death in muscular dystrophyKCNE2 forms potassium channels with KCNA3 and KCNQ1 in the choroid plexus epitheliumKCNE2 and the K (+) channel: the tail wagging the dogTargeted deletion of kcne2 impairs ventricular repolarization via disruption of I(K,slow1) and I(to,f)An LQTS6 MiRP1 mutation suppresses pacemaker current and is associated with sinus bradycardiaPostnatal development of dendritic synaptic integration in rat neocortical pyramidal neuronsFluvastatin reduces oxidative damage in human vascular endothelial cells by upregulating Bcl-2.K+ channel regulator KCR1 suppresses heart rhythm by modulating the pacemaker current If.Antibody therapeutics targeting ion channels: are we there yet?KCNE2 modulation of Kv4.3 current and its potential role in fatal rhythm disorders.Regulated expression of HCN channels and cAMP levels shape the properties of the h current in developing rat hippocampusThe membrane protein MiRP3 regulates Kv4.2 channels in a KChIP-dependent manner.Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits.Solution NMR of MPS-1 reveals a random coil cytosolic domain structureNovel exon 1 protein-coding regions N-terminally extend human KCNE3 and KCNE4.KCNE1 enhances phosphatidylinositol 4,5-bisphosphate (PIP2) sensitivity of IKs to modulate channel activity.A di-arginine ER retention signal regulates trafficking of HCN1 channels from the early secretory pathway to the plasma membrane.The physiological function of store-operated calcium entryTRIP8b is required for maximal expression of HCN1 in the mouse retinaThe fast and slow ups and downs of HCN channel regulation.Constitutively active Src tyrosine kinase changes gating of HCN4 channels through direct binding to the channel proteins.Distinct populations of HCN pacemaker channels produce voltage-dependent and voltage-independent currents.Regulation of gating and rundown of HCN hyperpolarization-activated channels by exogenous and endogenous PIP2The role of S4 charges in voltage-dependent and voltage-independent KCNQ1 potassium channel complexes.KCNE genetics and pharmacogenomics in cardiac arrhythmias: much ado about nothing?Transcription profiling of HCN-channel isotypes throughout mouse cardiac development.Rescue of a trafficking defective human pacemaker channel via a novel mechanism: roles of Src, Fyn, and Yes tyrosine kinases.Src tyrosine kinase alters gating of hyperpolarization-activated HCN4 pacemaker channel through Tyr531.Associated changes in HCN2 and HCN4 transcripts and I(f) pacemaker current in myocytes.Regulation of human cardiac potassium channels by full-length KCNE3 and KCNE4.
P2860
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P2860
MinK-related peptide 1: A beta subunit for the HCN ion channel subunit family enhances expression and speeds activation
description
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im Juni 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/06/22)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/06/22)
@nl
наукова стаття, опублікована в червні 2001
@uk
مقالة علمية (نشرت في 22-6-2001)
@ar
name
MinK-related peptide 1: A beta ...... pression and speeds activation
@ast
MinK-related peptide 1: A beta ...... pression and speeds activation
@en
MinK-related peptide 1: A beta ...... pression and speeds activation
@nl
type
label
MinK-related peptide 1: A beta ...... pression and speeds activation
@ast
MinK-related peptide 1: A beta ...... pression and speeds activation
@en
MinK-related peptide 1: A beta ...... pression and speeds activation
@nl
prefLabel
MinK-related peptide 1: A beta ...... pression and speeds activation
@ast
MinK-related peptide 1: A beta ...... pression and speeds activation
@en
MinK-related peptide 1: A beta ...... pression and speeds activation
@nl
P2093
P921
P356
P1433
P1476
MinK-related peptide 1: A beta ...... pression and speeds activation
@en
P2093
D. McKinnon
I. Potapova
I. S. Cohen
J. Zuckerman
M. R. El-Maghrabi
P304
P356
10.1161/HH1201.093511
P577
2001-06-22T00:00:00Z