Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus
about
Wnt signaling in development and diseaseZipper-interacting protein kinase (ZIPK) modulates canonical Wnt/beta-catenin signaling through interaction with Nemo-like kinase and T-cell factor 4 (NLK/TCF4)Comprehensive molecular characterization of human colon and rectal cancerA pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturationA missense mutation in PPARD causes a major QTL effect on ear size in pigsSOX9 inhibits β-TrCP-mediated protein degradation to promote nuclear GLI1 expression and cancer stem cell properties.Prognostic Significance of β-Catenin, E-Cadherin, and SOX9 in Colorectal Cancer: Results from a Large Population-Representative Series.Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties.Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilageSox proteins in melanocyte development and melanoma.SOX2 expression correlates with lymph-node metastases and distant spread in right-sided colon cancerStage-specific control of connective tissue growth factor (CTGF/CCN2) expression in chondrocytes by Sox9 and beta-catenin.Sox9 regulates hyperexpression of Wnt1 and Fzd1 in human osteosarcoma tissues and cells.p15RS attenuates Wnt/{beta}-catenin signaling by disrupting {beta}-catenin·TCF4 Interaction.Profiling spermatogenic failure in adult testes bearing Sox9-deficient Sertoli cells identifies genes involved in feminization, inflammation and stress.SOXC proteins amplify canonical WNT signaling to secure nonchondrocytic fates in skeletogenesis.The versatile functions of Sox9 in development, stem cells, and human diseasesMicrosatellite stable colorectal cancers stratified by the BRAF V600E mutation show distinct patterns of chromosomal instability.Strategies to minimize hypertrophy in cartilage engineering and regeneration.Interactions between SOX factors and Wnt/beta-catenin signaling in development and diseaseIntegrative analyses of conserved WNT clusters and their co-operative behaviour in human breast cancer.Sox9 directs hypertrophic maturation and blocks osteoblast differentiation of growth plate chondrocytesSOXC Transcription Factors Induce Cartilage Growth Plate Formation in Mouse Embryos by Promoting Noncanonical WNT Signaling.Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia.Gliotoxin Inhibits Proliferation and Induces Apoptosis in Colorectal Cancer Cells.Lawsonia intracellularis exploits β-catenin/Wnt and Notch signalling pathways during infection of intestinal crypt to alter cell homeostasis and promote cell proliferation.Abnormal expression of key genes and proteins in the canonical Wnt/β-catenin pathway of articular cartilage in a rat model of exercise-induced osteoarthritisSOX9 regulates low density lipoprotein receptor-related protein 6 (LRP6) and T-cell factor 4 (TCF4) expression and Wnt/β-catenin activation in breast cancer.KLF4 and SOX9 transcription factors antagonize β-catenin and inhibit TCF-activity in cancer cells.β-catenin and Kras/Foxm1 signaling pathway are critical to restrict Sox9 in basal cells during pulmonary branching morphogenesisInhibition of β-catenin signaling in chondrocytes induces delayed fracture healing in mice.Clinical applications of next-generation sequencing in colorectal cancersAntiangiogenic and antineuroinflammatory effects of kallistatin through interactions with the canonical Wnt pathway.The nuclear localization of glycogen synthase kinase 3β is required its putative PY-nuclear localization sequences.Significant Associations of SOX9 Gene Polymorphism and Gene Expression with the Risk of Osteonecrosis of the Femoral Head in a Han Population in Northern ChinaThe Signaling Pathways Involved in Chondrocyte Differentiation and Hypertrophic DifferentiationRoles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis.Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers.SoxE factors as multifunctional neural crest regulatory factors.Sox9 transcriptionally regulates Wnt signaling in intestinal epithelial stem cells in hypomethylated crypts in the diabetic state
P2860
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P2860
Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus
description
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2009
@ast
im Januar 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/01/30)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/01/30)
@nl
наукова стаття, опублікована в січні 2009
@uk
name
Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus
@ast
Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus
@en
Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus
@nl
type
label
Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus
@ast
Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus
@en
Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus
@nl
prefLabel
Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus
@ast
Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus
@en
Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus
@nl
P2093
P2860
P921
P3181
P356
P1476
Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus
@en
P2093
Lilia Topol
Timothy F. Day
Yingzi Yang
P2860
P304
P3181
P356
10.1074/JBC.M808048200
P407
P577
2009-01-30T00:00:00Z