Dendritic cell maturation and chemotaxis is regulated by TRPM2-mediated lysosomal Ca2+ release
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The role of STIM and ORAI proteins in phagocytic immune cellsTRPM2 Channel-Mediated ROS-Sensitive Ca(2+) Signaling Mechanisms in Immune CellsTargeting TRPM2 in ROS-Coupled DiseasesRecombinant tandem of pore-domains in a Weakly Inward rectifying K+ channel 2 (TWIK2) forms active lysosomal channels.Oxidant Sensing by TRPM2 Inhibits Neutrophil Migration and Mitigates InflammationP2X4 forms functional ATP-activated cation channels on lysosomal membranes regulated by luminal pH.TRPM2 cation channels modulate T cell effector functions and contribute to autoimmune CNS inflammation.A cell permeable NPE caged ADP-ribose for studying TRPM2Involvement of TRPM2 in peripheral nerve injury-induced infiltration of peripheral immune cells into the spinal cord in mouse neuropathic pain model.Role of TRP channels in the cardiovascular system.ADP-ribose/TRPM2-mediated Ca2+ signaling is essential for cytolytic degranulation and antitumor activity of natural killer cells.Calcium release through P2X4 activates calmodulin to promote endolysosomal membrane fusion.TRPM2 ion channels regulate macrophage polarization and gastric inflammation during Helicobacter pylori infection.Cell death and autophagy under oxidative stress: roles of poly(ADP-Ribose) polymerases and Ca(2+).Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedsideThe intracellular Ca²⁺ channels of membrane traffic.Divalent cation signaling in immune cellsThe TRPM2 ion channel, an oxidative stress and metabolic sensor regulating innate immunity and inflammation.What is the evidence for the role of TRP channels in inflammatory and immune cells?TRPM2-mediated intracellular Zn2+ release triggers pancreatic β-cell death.Renoprotection: focus on TRPV1, TRPV4, TRPC6 and TRPM2.Lys1110 of TRPM2 is critical for channel activation.A differential role of macrophage TRPM2 channels in Ca²⁺ signaling and cell death in early responses to H₂O₂.Targeting ion channels for the treatment of autoimmune neuroinflammation.The TRPM2 channel: A thermo-sensitive metabolic sensor.Emerging roles for TFEB in the immune response and inflammation.On the move, lysosomal CAX drives Ca2+ transport and motility.The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammationTRPM2 channels are not required for acute airway inflammation in OVA-induced severe allergic asthma in mice.TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1.Connecting Ca2+ and lysosomes to Parkinson disease.Structure-activity relationship of adenosine 5'-diphosphoribose at the transient receptor potential melastatin 2 (TRPM2) channel: rational design of antagonists.Different Principles of ADP-Ribose-Mediated Activation and Opposite Roles of the NUDT9 Homology Domain in the TRPM2 Orthologs of Man and Sea Anemone.Lysosomal Calcium in Neurodegeneration.Multiple molecular mechanisms form a positive feedback loop driving amyloid β42 peptide-induced neurotoxicity via activation of the TRPM2 channel in hippocampal neurons.Ins and outs of Ca2+ transport by acidic organelles and cell migration.The role of TRPM2 channels in neurons, glial cells and the blood-brain barrier in cerebral ischemia and hypoxia.TRPM2 and warmth sensation.TRPM2 in the Brain: Role in Health and DiseaseIon Channels and Transporters in Inflammation: Special Focus on TRP Channels and TRPC6
P2860
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P2860
Dendritic cell maturation and chemotaxis is regulated by TRPM2-mediated lysosomal Ca2+ release
description
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
@ast
im Oktober 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/10/01)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/10/01)
@nl
наукова стаття, опублікована в жовтні 2011
@uk
مقالة علمية (نشرت في أكتوبر 2011)
@ar
name
Dendritic cell maturation and ...... ediated lysosomal Ca2+ release
@ast
Dendritic cell maturation and ...... ediated lysosomal Ca2+ release
@en
Dendritic cell maturation and ...... ediated lysosomal Ca2+ release
@nl
type
label
Dendritic cell maturation and ...... ediated lysosomal Ca2+ release
@ast
Dendritic cell maturation and ...... ediated lysosomal Ca2+ release
@en
Dendritic cell maturation and ...... ediated lysosomal Ca2+ release
@nl
prefLabel
Dendritic cell maturation and ...... ediated lysosomal Ca2+ release
@ast
Dendritic cell maturation and ...... ediated lysosomal Ca2+ release
@en
Dendritic cell maturation and ...... ediated lysosomal Ca2+ release
@nl
P2093
P2860
P3181
P356
P1433
P1476
Dendritic cell maturation and ...... ediated lysosomal Ca2+ release
@en
P2093
Adriana Sumoza-Toledo
Andrea Fleig
Hanna Cortado
Harivadan Bhagat
Ingo Lange
Reinhold Penner
Santiago Partida-Sánchez
Yasuo Mori
P2860
P304
P3181
P356
10.1096/FJ.10-178483
P407
P577
2011-10-01T00:00:00Z