Two distinct phosphorylation pathways have additive effects on Abl family kinase activation
about
ABL tyrosine kinases: evolution of function, regulation, and specificityA single pulse of agrin triggers a pathway that acts to cluster acetylcholine receptorsRegulation of p73 by Hck through kinase-dependent and independent mechanismsCdo binds Abl to promote p38alpha/beta mitogen-activated protein kinase activity and myogenic differentiationAllosteric inhibition of the nonMyristoylated c-Abl tyrosine kinase by phosphopeptides derived from Abi1/Hssh3bp1Abelson phosphorylation of CLASP2 modulates its association with microtubules and actinRegulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contextsAbl Kinases Regulate HGF/Met Signaling Required for Epithelial Cell Scattering, Tubulogenesis and MotilityGene expression of human lung cancer cell line CL1-5 in response to a direct current electric fieldRole of ABL family kinases in cancer: from leukaemia to solid tumoursSynaptic clustering of PSD-95 is regulated by c-Abl through tyrosine phosphorylationArg kinase signaling in dendrite and synapse stabilization pathways: memory, cocaine sensitivity, and stressCortactin is involved in the entry of Coxiella burnetii into non-phagocytic cells.Functional mechanisms and roles of adaptor proteins in abl-regulated cytoskeletal actin dynamics.A dynamic view of domain-motif interactions.3BP2-deficient mice are osteoporotic with impaired osteoblast and osteoclast functionsPhosphorylation of Crk on tyrosine 251 in the RT loop of the SH3C domain promotes Abl kinase transactivationABL fusion oncogene transformation and inhibitor sensitivity are mediated by the cellular regulator RIN1.Regulation of actin polymerization and adhesion-dependent cell edge protrusion by the Abl-related gene (Arg) tyrosine kinase and N-WASp.Enhancement of ABL kinase catalytic efficiency by a direct binding regulator is independent of other regulatory mechanisms.Tyrosine phosphorylation in the SH3 domain disrupts negative regulatory interactions within the c-Abl kinase core.Src family kinases phosphorylate the Bcr-Abl SH3-SH2 region and modulate Bcr-Abl transforming activity.Transactivation of Abl by the Crk II adapter protein requires a PNAY sequence in the Crk C-terminal SH3 domain.Integrin signaling through Arg activates p190RhoGAP by promoting its binding to p120RasGAP and recruitment to the membrane.Interplay between kinase domain autophosphorylation and F-actin binding domain in regulating imatinib sensitivity and nuclear import of BCR-ABL.Global analysis of human nonreceptor tyrosine kinase specificity using high-density peptide microarrays.An EGFR-Src-Arg-cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion.Abl2/Abl-related gene stabilizes actin filaments, stimulates actin branching by actin-related protein 2/3 complex, and promotes actin filament severing by cofilin.Direct interactions with the integrin β1 cytoplasmic tail activate the Abl2/Arg kinase.Structure of the ABL2/ARG kinase in complex with dasatinibDisclosure of erlotinib as a multikinase inhibitor in pancreatic ductal adenocarcinoma.Dysregulated Dscam levels act through Abelson tyrosine kinase to enlarge presynaptic arborsControlling Abl: auto-inhibition and co-inhibition?Identification of targets of c-Src tyrosine kinase by chemical complementation and phosphoproteomicsCrk and ABI1: binary molecular switches that regulate abl tyrosine kinase and signaling to the cytoskeleton.Emerging drugs in chronic myelogenous leukaemia.A peptide photoaffinity probe specific for the active conformation of the Abl tyrosine kinase.Emerging therapeutic options for Philadelphia-positive acute lymphocytic leukemia.β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation.Src-family kinases in the development and therapy of Philadelphia chromosome-positive chronic myeloid leukemia and acute lymphoblastic leukemia.
P2860
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P2860
Two distinct phosphorylation pathways have additive effects on Abl family kinase activation
description
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im Juni 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/06/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/06/01)
@nl
наукова стаття, опублікована в червні 2003
@uk
مقالة علمية (نشرت في يونيو 2003)
@ar
name
Two distinct phosphorylation p ...... n Abl family kinase activation
@ast
Two distinct phosphorylation p ...... n Abl family kinase activation
@en
Two distinct phosphorylation p ...... n Abl family kinase activation
@nl
type
label
Two distinct phosphorylation p ...... n Abl family kinase activation
@ast
Two distinct phosphorylation p ...... n Abl family kinase activation
@en
Two distinct phosphorylation p ...... n Abl family kinase activation
@nl
prefLabel
Two distinct phosphorylation p ...... n Abl family kinase activation
@ast
Two distinct phosphorylation p ...... n Abl family kinase activation
@en
Two distinct phosphorylation p ...... n Abl family kinase activation
@nl
P2093
P2860
P1476
Two distinct phosphorylation p ...... n Abl family kinase activation
@en
P2093
Anthony J. Koleske
Darren Veach
Henry S. Duewel
Keith Q. Tanis
William G. Bornmann
P2860
P304
P356
10.1128/MCB.23.11.3884-3896.2003
P407
P577
2003-06-01T00:00:00Z