The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity
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ABL tyrosine kinases: evolution of function, regulation, and specificityPrdx1 inhibits tumorigenesis via regulating PTEN/AKT activityAbl interactor 1 binds to sos and inhibits epidermal growth factor- and v-Abl-induced activation of extracellular signal-regulated kinasesOncogenic activation of c-Abl in non-small cell lung cancer cells lacking FUS1 expression: inhibition of c-Abl by the tumor suppressor gene product Fus1Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contextsCrystal structure of a multifunctional 2-Cys peroxiredoxin heme-binding protein 23 kDa/proliferation-associated gene productDimer-oligomer interconversion of wild-type and mutant rat 2-Cys peroxiredoxin: disulfide formation at dimer-dimer interfaces is not essential for decamerizationDistinct physiological functions of thiol peroxidase isoenzymes in Saccharomyces cerevisiae.Peroxiredoxin 1 - an antioxidant enzyme in cancerHuman peroxiredoxin 1 and 2 are not duplicate proteins: the unique presence of CYS83 in Prx1 underscores the structural and functional differences between Prx1 and Prx2Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppressionRegulation of Cbl phosphorylation by the Abl tyrosine kinase and the Nck SH2/SH3 adaptorRole of the PLA2-independent peroxiredoxin VI activity in the survival of immortalized fibroblasts exposed to cytotoxic oxidative stressThioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signalingMechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative diseaseRole of ABL family kinases in cancer: from leukaemia to solid tumoursUnc119 protects from Shigella infection by inhibiting the Abl family kinasesAn additional cysteine in a typical 2-Cys peroxiredoxin of Pseudomonas promotes functional switching between peroxidase and molecular chaperoneDual role of peroxiredoxin I in macrophage-derived foam cellsDifferential cellular and subcellular localization of heme-binding protein 23/peroxiredoxin I and heme oxygenase-1 in rat liverTwo distinct phosphorylation pathways have additive effects on Abl family kinase activationRoles of peroxiredoxin II in the regulation of proinflammatory responses to LPS and protection against endotoxin-induced lethal shockSignal transduction by reactive oxygen speciesIntramolecular dynamics within the N-Cap-SH3-SH2 regulatory unit of the c-Abl tyrosine kinase reveal targeting to the cellular membraneC3G forms complexes with Bcr-Abl and p38α MAPK at the focal adhesions in chronic myeloid leukemia cells: implication in the regulation of leukemic cell adhesion.Role of SHP-2 tyrosine phosphatase in the DNA damage-induced cell death response.Mutational analysis of the regulatory function of the c-Abl Src homology 3 domain.Inhibition of v-Abl transformation in 3T3 cells overexpressing different forms of the Abelson interactor protein Abi-1.Crk family adaptor proteins trans-activate c-Abl kinase.The kinase-deficient Src acts as a suppressor of the Abl kinase for Cbl phosphorylationInteraction of the N-methyl-D-aspartic acid receptor NR2D subunit with the c-Abl tyrosine kinase.Bcr-Abl with an SH3 deletion retains the ability To induce a myeloproliferative disease in mice, yet c-Abl activated by an SH3 deletion induces only lymphoid malignancyActivation of the Abl tyrosine kinase in vivo by Src homology 3 domains from the Src homology 2/Src homology 3 adaptor Nck.Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer.The protein interaction of Saccharomyces cerevisiae cytoplasmic thiol peroxidase II with SFH2p and its in vivo function.Cyclophilin a binds to peroxiredoxins and activates its peroxidase activity.Aph2, a protein with a zf-DHHC motif, interacts with c-Abl and has pro-apoptotic activity.Augmented expression of peroxiredoxin VI in rat lung and kidney after birth implies an antioxidative role.The pag gene product, a physiological inhibitor of c-abl tyrosine kinase, is overexpressed in cells entering S phase and by contact with agents inducing oxidative stress.Identification and characterization of potential new therapeutic targets in inflammatory and autoimmune diseases.
P2860
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P2860
The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The PAG gene product, a stress ...... c-Abl tyrosine kinase activity
@ast
The PAG gene product, a stress ...... c-Abl tyrosine kinase activity
@en
The PAG gene product, a stress ...... c-Abl tyrosine kinase activity
@nl
type
label
The PAG gene product, a stress ...... c-Abl tyrosine kinase activity
@ast
The PAG gene product, a stress ...... c-Abl tyrosine kinase activity
@en
The PAG gene product, a stress ...... c-Abl tyrosine kinase activity
@nl
prefLabel
The PAG gene product, a stress ...... c-Abl tyrosine kinase activity
@ast
The PAG gene product, a stress ...... c-Abl tyrosine kinase activity
@en
The PAG gene product, a stress ...... c-Abl tyrosine kinase activity
@nl
P2860
P356
P1433
P1476
The PAG gene product, a stress ...... c-Abl tyrosine kinase activity
@en
P2093
R A Van Etten
P2860
P304
P356
10.1101/GAD.11.19.2456
P407
P577
1997-10-01T00:00:00Z