Mouse models for hereditary nonpolyposis colorectal cancer
about
DNA mismatch repair: molecular mechanism, cancer, and ageingMouse models for the discovery of colorectal cancer driver genesModeling the study of DNA damage responses in miceInactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterilitySomatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cellsMsh2 status modulates both apoptosis and mutation frequency in the murine small intestineEfficient repair of A/C mismatches in mouse cells deficient in long-patch mismatch repairThe absence of Msh2 alters abelson virus pre-B-cell transformation by influencing p53 mutationChromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors.Genetic susceptibility to non-polyposis colorectal cancer.Suspected Lynch syndrome associated MSH6 variants: A functional assay to determine their pathogenicityTumour suppressor gene mutations in humans and mice: parallels and contrastsThe clonal origin and clonal evolution of epithelial tumours.Genotype to phenotype: analyzing the effects of inherited mutations in colorectal cancer families.Loss of DNA mismatch repair imparts a selective advantage in planarian adult stem cells.Tumor characteristics as an analytic tool for classifying genetic variants of uncertain clinical significance.Novel translational strategies in colorectal cancer research.DNA mismatch repair and infertilityFunctional analysis in mouse embryonic stem cells reveals wild-type activity for three MSH6 variants found in suspected Lynch syndrome patients.Methylation-induced G(2)/M arrest requires a full complement of the mismatch repair protein hMLH1Microsatellite instability in Drosophila spellchecker1 (MutS homolog) mutants.Molecular devices for high fidelity of DNA replication and gene expression.Point: From animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system.Mouse MutS-like protein Msh5 is required for proper chromosome synapsis in male and female meiosis.Mononucleotide microsatellite instability and germline MSH6 mutation analysis in early onset colorectal cancerEndometrial and colorectal tumors from patients with hereditary nonpolyposis colon cancer display different patterns of microsatellite instabilityTolerance of human MSH2+/- lymphoblastoid cells to the methylating agent temozolomide.Mouse embryonic stem cells carrying one or two defective Msh2 alleles respond abnormally to oxidative stress inflicted by low-level radiationOligonucleotide-directed mutagenesis screen to identify pathogenic Lynch syndrome-associated MSH2 DNA mismatch repair gene variants.Biallelic mutation of MSH2 in primary human cells is associated with sensitivity to irradiation and altered RAD51 foci kinetics.Nit1 and Fhit tumor suppressor activities are additive.The mutator pathway is a feature of immunodeficiency-related lymphomas.Generation of a mouse mutant by oligonucleotide-mediated gene modification in ES cells.Prostaglandin E(2) stimulates progression-related gene expression in early colorectal adenoma cells.Haploinsufficiency of Tumor Suppressor Genes is Driven by the Cumulative Effect of microRNAs, microRNA Binding Site Polymorphisms and microRNA Polymorphisms: An In silico Approach.Assessment of acridine orange and SYTO 16 for in vivo imaging of the peritoneal tissues in mice.Microsatellite Instability in Mouse Models of Colorectal Cancer.
P2860
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P2860
Mouse models for hereditary nonpolyposis colorectal cancer
description
1998 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
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im Januar 1998 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 1998/01/15)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/01/15)
@nl
наукова стаття, опублікована в січні 1998
@uk
مقالة علمية (نشرت في 15-1-1998)
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name
Mouse models for hereditary nonpolyposis colorectal cancer
@ast
Mouse models for hereditary nonpolyposis colorectal cancer
@en
Mouse models for hereditary nonpolyposis colorectal cancer
@nl
type
label
Mouse models for hereditary nonpolyposis colorectal cancer
@ast
Mouse models for hereditary nonpolyposis colorectal cancer
@en
Mouse models for hereditary nonpolyposis colorectal cancer
@nl
prefLabel
Mouse models for hereditary nonpolyposis colorectal cancer
@ast
Mouse models for hereditary nonpolyposis colorectal cancer
@en
Mouse models for hereditary nonpolyposis colorectal cancer
@nl
P2093
P1433
P1476
Mouse models for hereditary nonpolyposis colorectal cancer
@en
P2093
te Riele H
van Rossum A
van der Valk M
P304
P407
P577
1998-01-01T00:00:00Z