Dynamics of major histocompatibility complex class II compartments during B cell receptor-mediated cell activation
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Polarity protein Par3 controls B-cell receptor dynamics and antigen extraction at the immune synapse.Syk-dependent actin dynamics regulate endocytic trafficking and processing of antigens internalized through the B-cell receptorVamp-7-dependent secretion at the immune synapse regulates antigen extraction and presentation in B-lymphocytes.Components of the antigen processing and presentation pathway revealed by gene expression microarray analysis following B cell antigen receptor (BCR) stimulationB cell antigen receptor signaling and internalization are mutually exclusive events.Immunogenicity to biologics: mechanisms, prediction and reduction.How B cells capture, process and present antigens: a crucial role for cell polarity.Monovalent ligation of the B cell receptor induces receptor activation but fails to promote antigen presentation.Recruitment of Cbl-b to B cell antigen receptor couples antigen recognition to Toll-like receptor 9 activation in late endosomes.Human cathepsin S, but not cathepsin L, degrades efficiently MHC class II-associated invariant chain in nonprofessional APCsB cells and autoantibodies in the pathogenesis of multiple sclerosis and related inflammatory demyelinating diseasesThe Syk-binding ubiquitin ligase c-Cbl mediates signaling-dependent B cell receptor ubiquitination and B cell receptor-mediated antigen processing and presentation.The actin-based motor protein myosin II regulates MHC class II trafficking and BCR-driven antigen presentation.T cell-induced secretion of MHC class II-peptide complexes on B cell exosomes.The B cell receptor governs the subcellular location of Toll-like receptor 9 leading to hyperresponses to DNA-containing antigensIndependent trafficking of Ig-alpha/Ig-beta and mu-heavy chain is facilitated by dissociation of the B cell antigen receptor complexThe cytoskeleton coordinates the early events of B-cell activation.Receptors, subcellular compartments and the regulation of peripheral B cell responses: the illuminating state of anergy.Early BCR Events and Antigen Capture, Processing, and Loading on MHC Class II on B Cells.The ins and outs of MHC class II-mediated antigen processing and presentation.B Cells use Conserved Polarity Cues to Regulate Their Antigen Processing and Presentation Functions.Studying MHC class II presentation of immobilized antigen by B lymphocytes.The Other Function: Class II-Restricted Antigen Presentation by B Cells.The transmembrane tyrosine of micro-heavy chain is required for BCR destabilization and entry of antigen into clathrin-coated vesicles.A mutation in Epstein-Barr virus LMP2A reveals a role for phospholipase D in B-Cell antigen receptor trafficking.BCR-bound antigen is targeted to exosomes in human follicular lymphoma B-cells.PLD2 is enriched on exosomes and its activity is correlated to the release of exosomes.The effect of B cell receptor signaling on antigen endocytosis and processing.Germinal center B cells regulate their capability to present antigen by modulation of HLA-DO.Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane.Exosomes and Immune Response in Cancer: Friends or Foes?Phosphoinositide 3-Kinase Activation by Igβ Controls de Novo Formation of an Antigen-processing CompartmentDendritic cells, but not macrophages or B cells, activate major histocompatibility complex class II-restricted CD4+ T cells upon immune-complex uptake in vivo
P2860
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P2860
Dynamics of major histocompatibility complex class II compartments during B cell receptor-mediated cell activation
description
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im Februar 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/02/18)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/02/18)
@nl
наукова стаття, опублікована в лютому 2002
@uk
مقالة علمية (نشرت في 18-2-2002)
@ar
name
Dynamics of major histocompati ...... eptor-mediated cell activation
@ast
Dynamics of major histocompati ...... eptor-mediated cell activation
@en
Dynamics of major histocompati ...... eptor-mediated cell activation
@nl
type
label
Dynamics of major histocompati ...... eptor-mediated cell activation
@ast
Dynamics of major histocompati ...... eptor-mediated cell activation
@en
Dynamics of major histocompati ...... eptor-mediated cell activation
@nl
prefLabel
Dynamics of major histocompati ...... eptor-mediated cell activation
@ast
Dynamics of major histocompati ...... eptor-mediated cell activation
@en
Dynamics of major histocompati ...... eptor-mediated cell activation
@nl
P2093
P2860
P50
P921
P356
P1476
Dynamics of major histocompati ...... eptor-mediated cell activation
@en
P2093
Christian Bonnerot
Danielle Lankar
Graça Raposo
Hélène Vincent-Schneider
Takeaki Yokozeki
P2860
P304
P356
10.1084/JEM.20011543
P407
P577
2002-02-18T00:00:00Z