An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.
about
Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidaseActivation of human prolegumain by cleavage at a C-terminal asparagine residueGranzyme B cleavage of autoantigens in autoimmunityThe phagosome proteome: insight into phagosome functionsCathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravisAsparagine endopeptidase controls anti-influenza virus immune responses through TLR7 activationIrAE – An asparaginyl endopeptidase (legumain) in the gut of the hard tick Ixodes ricinusMechanistic and structural studies on legumain explain its zymogenicity, distinct activation pathways, and regulationStructural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stageBiosynthetic processing of cathepsins and lysosomal degradation are abolished in asparaginyl endopeptidase-deficient miceDynamics of major histocompatibility complex class II compartments during B cell receptor-mediated cell activationProteases involved in MHC class II antigen presentationInhibition of mammalian legumain by Michael acceptors and AzaAsn-halomethylketones.Classification of the caspase-hemoglobinase fold: detection of new families and implications for the origin of the eukaryotic separins.Characterization of legumain.Distribution of productive antigen-processing activity for MHC class II presentation in macrophages.Specificity of human cathepsin S determined by processing of peptide substrates and MHC class II-associated invariant chain.Two secreted cystatins of the soft tick Ornithodoros moubata: differential expression pattern and inhibitory specificity.Helper T cell epitope-mapping reveals MHC-peptide binding affinities that correlate with T helper cell responses to pneumococcal surface protein A.Blastocystis legumain is localized on the cell surface, and specific inhibition of its activity implicates a pro-survival role for the enzyme.The ovarian transcriptome of the cattle tick, Rhipicephalus (Boophilus) microplus, feeding upon a bovine host infected with Babesia bovisThe role of lysosomal proteinases in MHC class II-mediated antigen processing and presentation.Expanded nonhuman primate tregs exhibit a unique gene expression signature and potently downregulate alloimmune responsesTranscriptome of American oysters, Crassostrea virginica, in response to bacterial challenge: insights into potential mechanisms of disease resistanceRegulated expression and intracellular localization of cystatin F in human U937 cells.Multistep autoactivation of asparaginyl endopeptidase in vitro and in vivo.Immunological genomics of Brugia malayi: filarial genes implicated in immune evasion and protective immunity.Thymus-specific serine protease contributes to the diversification of the functional endogenous CD4 T cell receptor repertoire.Asparagine endopeptidase is an innovative therapeutic target for neurodegenerative diseases.Nuclear legumain activity in colorectal cancer.Divergent paths for the selection of immunodominant epitopes from distinct antigenic sources.Complex genomic alterations and gene expression in acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21.Processing and activation of lysosomal proteinases.The asparaginyl endopeptidase legumain is essential for functional recovery after spinal cord injury in adult zebrafish.Localization of CD4+ T cell epitope hotspots to exposed strands of HIV envelope glycoprotein suggests structural influences on antigen processingParasitic helminth cystatin inhibits DSS-induced intestinal inflammation via IL-10(+)F4/80(+) macrophage recruitment.The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules.The processing of antigens delivered as DNA vaccines.Dendritic cells, pro-inflammatory responses, and antigen presentation in a rodent malaria infection.Helminth parasites--masters of regulation.
P2860
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P2860
An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.
@ast
An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.
@en
An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.
@nl
type
label
An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.
@ast
An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.
@en
An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.
@nl
prefLabel
An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.
@ast
An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.
@en
An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.
@nl
P2093
P2860
P50
P356
P1433
P1476
An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation
@en
P2093
P2860
P2888
P304
P356
10.1038/25379
P407
P577
1998-12-01T00:00:00Z
P6179
1026130190