Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin
about
Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a-dependent neurite outgrowthWnt/beta-catenin signaling and small molecule inhibitorsIQGAP1 functions as a modulator of dishevelled nuclear localization in Wnt signalingThe ciliary protein nephrocystin-4 translocates the canonical Wnt regulator Jade-1 to the nucleus to negatively regulate β-catenin signalingInteractions between Casein kinase Iepsilon (CKIepsilon) and two substrates from disparate signaling pathways reveal mechanisms for substrate-kinase specificityWnt5a regulates midbrain dopaminergic axon growth and guidanceThe extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivoWnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice.IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ɛ and Wnt/β-catenin independent inhibition of mitotic spindle formation.Asymmetry of VANGL2 in migrating lymphocytes as a tool to monitor activity of the mammalian WNT/planar cell polarity pathway.beta-Arrestins - scaffolds and signalling elements essential for WNT/Frizzled signalling pathways?Dishevelled-3 phosphorylation is governed by HIPK2/PP1Cα/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma.Functional analysis of dishevelled-3 phosphorylation identifies distinct mechanisms driven by casein kinase 1ϵ and frizzled5.Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6.Sequential activation and inactivation of Dishevelled in the Wnt/beta-catenin pathway by casein kinases.WNT signaling in activated microglia is proinflammatory.Parameter-free methods distinguish Wnt pathway models and guide design of experiments.Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo.Autocrine Signaling by Wnt-5a Deregulates Chemotaxis of Leukemic Cells and Predicts Clinical Outcome in Chronic Lymphocytic LeukemiaMultiple PPPS/TP motifs act in a combinatorial fashion to transduce Wnt signaling through LRP6.Assembly of Dishevelled 3-based supermolecular complexes via phosphorylation and Axin.Functional consequences of Wnt-induced dishevelled 2 phosphorylation in canonical and noncanonical Wnt signaling.Therapeutic targeting of casein kinase 1δ in breast cancerModeling Intercellular Communication as a Survival Strategy of Cancer Cells: An In Silico Approach on a Flexible Bioinformatics Framework.Nato3 integrates with the Shh-Foxa2 transcriptional network regulating the differentiation of midbrain dopaminergic neurons.Quantitative and kinetic profile of Wnt/β-catenin signaling components during human neural progenitor cell differentiation.Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathwaysTriple SILAC to determine stimulus specific interactions in the Wnt pathway.Simplified protocol for flow cytometry analysis of fluorescently labeled exosomes and microvesicles using dedicated flow cytometer.Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates.DVL as a scaffold protein capturing classical GPCRs.Expression of COBLL1 encoding novel ROR1 binding partner is robust predictor of survival in chronic lymphocytic leukemia.Chemical Enhancement of In Vitro and In Vivo Direct Cardiac Reprogramming.Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.WWC3 regulates the Wnt and Hippo pathways via Dishevelled proteins and large tumour suppressor 1, to suppress lung cancer invasion and metastasis.Changes in tau phosphorylation in hibernating rodents.Post-translational modifications regulate signalling by Ror1.
P2860
Q24297657-53F28C8E-2ECC-4223-8482-FE6AA352C443Q24597197-8B9FA8B4-1241-4020-952E-D394B674706CQ27329002-4B6B7B76-938B-4B21-89B8-1101F9369A8DQ28116639-B0BF3C0B-A3F6-4ADB-8B76-B3D9325A7BAEQ28474981-520416B1-D8F4-478A-8D05-7A721F40B818Q28568522-29734107-C6FC-4BC8-A7B0-4D3275B9808EQ28588070-25A069FB-9156-4B9D-9F0B-2B69D866ADACQ30480781-3E77200D-9A7A-4C34-B537-38DA194AC485Q30500880-09DEBE3C-14B7-4652-BBB6-176AF92A9758Q30619502-4C3C5646-18FE-464D-B841-53B5FE71E7CFQ33730604-E809CBDF-6DE2-46BB-9A78-6FC9CEBD61E3Q33889222-6B27F400-BD69-4458-9019-061503BD5243Q34141145-5C73C7D3-3B76-40B3-B55E-C0E648E3A76AQ34484412-1AE0AD39-A2EB-42DE-8575-7D48F03968EBQ34695767-15B9C2D0-3193-4335-9498-8455AEC05EC1Q34722036-9454F2D7-840B-45A6-BE48-22C14000DA43Q35157066-C717274C-A982-4D5B-A1FC-BF8D81E0AE82Q35800324-4827F5DD-F9FB-4FB5-A4F3-3A3A114D4BE3Q36471596-367BBF74-D4E2-4EEA-A68C-77A8CCB7FE45Q36496905-5543E993-BAF8-4687-8AAA-FA94B85B92B8Q36523966-41E58EFA-978D-4E0D-889B-212FD2BDCCA2Q36725106-2FFB002C-E63D-443E-9AA8-9B79E25E644EQ36734385-A0B72E04-2590-4DEC-AE48-F62EA7AEFBFFQ38892442-5CF57853-A6F4-48A6-BEE3-1E238A3DE66FQ39223325-13B3190D-14D0-480A-97EB-11E1AEEA38A7Q39497356-79823A9E-4A36-40ED-BA03-5FCE9B4DD653Q39924848-63379473-6BAB-4595-9357-D906D2B553E8Q40832860-4A0DC3C8-43E1-4689-9273-B3397BAD264BQ41126279-944D2267-EAB2-4EBF-9286-25FA8A8E758EQ41497717-942DB9EF-14D8-4E88-A42A-0E16E9708DA3Q42598026-49208F87-43EC-401A-8712-154D9D06B943Q45874243-826EE35F-5DA0-4E1A-866B-B74CF8A47FB2Q46195954-777E1289-E264-4538-848B-62B44441D227Q47723054-2391377C-4E8C-4479-B2D2-C7CB79A5A961Q48099481-4DDB7AF7-67DB-4FEC-A3CC-E6DEFDA3C4B7Q51053890-A5133C90-DF7F-41F7-9B76-A58CDE653CA1Q51768578-B9EAA919-73BB-4186-B76B-7C78076B192E
P2860
Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin
description
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im März 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/03/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/03/01)
@nl
наукова стаття, опублікована в березні 2007
@uk
مقالة علمية (نشرت في مارس 2007)
@ar
name
Wnt-3a utilizes a novel low do ...... f Dvl to activate beta-catenin
@ast
Wnt-3a utilizes a novel low do ...... f Dvl to activate beta-catenin
@en
Wnt-3a utilizes a novel low do ...... f Dvl to activate beta-catenin
@nl
type
label
Wnt-3a utilizes a novel low do ...... f Dvl to activate beta-catenin
@ast
Wnt-3a utilizes a novel low do ...... f Dvl to activate beta-catenin
@en
Wnt-3a utilizes a novel low do ...... f Dvl to activate beta-catenin
@nl
prefLabel
Wnt-3a utilizes a novel low do ...... f Dvl to activate beta-catenin
@ast
Wnt-3a utilizes a novel low do ...... f Dvl to activate beta-catenin
@en
Wnt-3a utilizes a novel low do ...... f Dvl to activate beta-catenin
@nl
P921
P1433
P1476
Wnt-3a utilizes a novel low do ...... f Dvl to activate beta-catenin
@en
P2093
Vítezslav Bryja
P304
P356
10.1016/J.CELLSIG.2006.08.011
P577
2007-03-01T00:00:00Z