bcl-2 deficiency in mice leads to pleiotropic abnormalities: accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestine
about
Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family membersA cloning method for caspase substrates that uses the yeast two-hybrid system: cloning of the antiapoptotic gene gelsolinAttenuation of both apoptotic and necrotic actions of cadmium by Bcl-2.Melanocyte stem cells as potential therapeutics in skin disordersSolution structure of the antiapoptotic protein bcl-2Apoptosis during an early stage of nephrogenesis induces renal hypoplasia in bcl-2-deficient miceLoss of PKD1 and loss of Bcl-2 elicit polycystic kidney disease through distinct mechanismsBCL-2 is dispensable for thrombopoiesis and platelet survivalCorrelation between Mcl-1 and pAKT protein expression in colorectal cancer.Influence of the site of small bowel resection on intestinal epithelial cell apoptosis.The pro-apoptotic protein Bim is a microRNA target in kidney progenitors.Polycystic kidney disease in SBM transgenic mice: role of c-myc in disease induction and progression.Immunohistochemical analysis of Mcl-1 protein in human tissues. Differential regulation of Mcl-1 and Bcl-2 protein production suggests a unique role for Mcl-1 in control of programmed cell death in vivo.Overexpression of Bcl-2 protects from ultraviolet B-induced apoptosis but promotes hair follicle regression and chemotherapy-induced alopecia.Endogenous bcl-2 is not required for the development of Emu-myc-induced B-cell lymphomaInvolvement of Fas in regression of vaginal epithelia after ovariectomy and during an estrous cycle.Loss of GM3 synthase gene, but not sphingosine kinase 1, is protective against murine nephronophthisis-related polycystic kidney disease.Bcl-2 expression identifies an early stage of myogenesis and promotes clonal expansion of muscle cells.bcl-x prevents apoptotic cell death of both primitive and definitive erythrocytes at the end of maturation.Peripheral deletion of autoreactive CD8 T cells by cross presentation of self-antigen occurs by a Bcl-2-inhibitable pathway mediated by BimLoss of Bim allows precursor B cell survival but not precursor B cell differentiation in the absence of interleukin 7Effects of Helicobacter pylori infection on gastric epithelial cell kinetics in patients with chronic renal failure.Apoptosis regulator bcl-w is essential for spermatogenesis but appears otherwise redundantThe tissue dependent interactions between p53 and Bcl-2 in vivo.Attacking cancer's Achilles heel: antagonism of anti-apoptotic BCL-2 family membersGlucocorticoid-induced apoptosis of healthy and malignant lymphocytes.Bcl-2 is a critical mediator of intestinal transformationIntracellular death platform steps-in: targeting prostate tumors via endoplasmic reticulum (ER) apoptosis.Tonic activation of Bax primes neural progenitors for rapid apoptosis through a mechanism preserved in medulloblastomaBrief report: increased apoptosis in advanced atherosclerotic lesions of Apoe-/- mice lacking macrophage Bcl-2.Regulation of the autophagic bcl-2/beclin 1 interaction.Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells.Mitochondria-mediated apoptosis in mammals.The regulation of apoptosis in kidney development: implications for nephron number and pattern?Lessons from gain- and loss-of-function models of pro-survival Bcl2 family proteins: implications for targeted therapy.Bim gene dosage is critical in modulating nephron progenitor survival in the absence of microRNAs during kidney development.Epstein-Barr virus encodes a novel homolog of the bcl-2 oncogene that inhibits apoptosis and associates with Bax and Bak.Kinase cascades regulating entry into apoptosis.Bcl-2 antiapoptotic protein mediates verotoxin II-induced cell death: possible association between bcl-2 and tissue failure by E. coli O157:H7.Experimental pneumococcal meningitis: impaired clearance of bacteria from the blood due to increased apoptosis in the spleen in Bcl-2-deficient mice.
P2860
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P2860
bcl-2 deficiency in mice leads to pleiotropic abnormalities: accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestine
description
1995 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1995
@ast
im Januar 1995 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1995/01/15)
@sk
vědecký článek publikovaný v roce 1995
@cs
wetenschappelijk artikel (gepubliceerd op 1995/01/15)
@nl
наукова стаття, опублікована в січні 1995
@uk
مقالة علمية (نشرت في 15-1-1995)
@ar
name
bcl-2 deficiency in mice leads ...... and distorted small intestine
@ast
bcl-2 deficiency in mice leads ...... and distorted small intestine
@en
bcl-2 deficiency in mice leads ...... and distorted small intestine
@nl
type
label
bcl-2 deficiency in mice leads ...... and distorted small intestine
@ast
bcl-2 deficiency in mice leads ...... and distorted small intestine
@en
bcl-2 deficiency in mice leads ...... and distorted small intestine
@nl
prefLabel
bcl-2 deficiency in mice leads ...... and distorted small intestine
@ast
bcl-2 deficiency in mice leads ...... and distorted small intestine
@en
bcl-2 deficiency in mice leads ...... and distorted small intestine
@nl
P2093
P1433
P1476
bcl-2 deficiency in mice leads ...... and distorted small intestine
@en
P2093
A. Shimono
T. Takahashi
T. Tsujimura
Y. Kitamura
Y. Tsujimoto
P304
P407
P577
1995-01-15T00:00:00Z