Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin
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Gain-of-function mutations of ARHGAP31, a Cdc42/Rac1 GTPase regulator, cause syndromic cutis aplasia and limb anomaliesMore than one way to skin . .Scratching the surface of skin developmentNotch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinasesTissue patterning and cellular mechanicsYap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney developmentCdc42 in oncogenic transformation, invasion, and tumorigenesisThe Rho-GTPase cdc42 regulates neural progenitor fate at the apical surfacePlanar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary ciliaThe small GTPase Cdc42 interacts with Niemann-Pick C1-like 1 (NPC1L1) and controls its movement from endocytic recycling compartment to plasma membrane in a cholesterol-dependent mannerCDC42 is required for structural patterning of the lung during developmentCdc42 and Gsk3 modulate the dynamics of radial glial growth, inter-radial glial interactions and polarity in the developing cerebral cortex.Cdc42 controls vascular network assembly through protein kinase Cι during embryonic vasculogenesis.Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes.Cdc42 is a key regulator of B cell differentiation and is required for antiviral humoral immunity.Neural Wiskott-Aldrich syndrome protein modulates Wnt signaling and is required for hair follicle cycling in micePilot study on the effects of dietary conjugated linoleic acid on tumorigenesis and gene expression in PyMT transgenic mice.Concise review: polarity in stem cells, disease, and aging.Aberrant regulation of planar cell polarity in polycystic kidney diseaseSignaling role of Cdc42 in regulating mammalian physiology.CDC42 is required for tissue lamination and cell survival in the mouse retina.RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytesLive imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation.Gene targeting of Cdc42 and Cdc42GAP affirms the critical involvement of Cdc42 in filopodia induction, directed migration, and proliferation in primary mouse embryonic fibroblasts.Pleiotropic functions of Rho GTPase signaling: a Trojan horse or Achilles' heel for breast cancer treatment?The Rho GTPase Cdc42 regulates hair cell planar polarity and cellular patterning in the developing cochlea.Retinal degeneration modulates intracellular localization of CDC42 in photoreceptorsCdc42 GTPase-activating protein deficiency promotes genomic instability and premature aging-like phenotypesRho GTPase Cdc42 coordinates hematopoietic stem cell quiescence and niche interaction in the bone marrow.The Rho GTPase Cdc42 is required for primary mammary epithelial cell morphogenesis in vitro.Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice.Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling.Increased hematopoietic stem cell mobilization in aged mice.Podocyte-specific loss of Cdc42 leads to congenital nephropathyEssential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development.Rho GTPases in embryonic developmentCdc42-dependent actin dynamics controls maturation and secretory activity of dendritic cellsCdc42 regulates epithelial cell polarity and cytoskeletal function during kidney tubule development.Cdc42-dependent structural development of auditory supporting cells is required for wound healing at adulthood.Myelin is dependent on the Charcot-Marie-Tooth Type 4H disease culprit protein FRABIN/FGD4 in Schwann cells
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P2860
Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin
description
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im März 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/03/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/03/01)
@nl
наукова стаття, опублікована в березні 2006
@uk
مقالة علمية (نشرت في مارس 2006)
@ar
name
Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin
@ast
Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin
@en
Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin
@nl
type
label
Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin
@ast
Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin
@en
Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin
@nl
prefLabel
Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin
@ast
Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin
@en
Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin
@en
P2093
Aleksandra Czuchra
Anna Chrostek
Hannelore Meyer
Lutz Langbein
Tine Lefever
P2860
P304
P3181
P356
10.1101/GAD.361406
P577
2006-03-01T00:00:00Z