cPGES/p23 is required for glucocorticoid receptor function and embryonic growth but not prostaglandin E2 synthesis
about
Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid effectsHigh levels of Hsp90 cochaperone p23 promote tumor progression and poor prognosis in breast cancer by increasing lymph node metastases and drug resistancePolyunsaturated fatty acid metabolism in prostate cancerEnzymes of the cyclooxygenase pathways of prostanoid biosynthesisChaperoning steroidal physiology: lessons from mouse genetic models of Hsp90 and its cochaperonesMice lacking mPGES-1 are resistant to lithium-induced polyuria.The impact of microsomal prostaglandin e synthase 1 on blood pressure is determined by genetic background.Prostaglandin E2 synthases in neurologic homeostasis and diseaseDefective glucocorticoid receptor signaling and keratinocyte-autonomous defects contribute to skin phenotype of mouse embryos lacking the Hsp90 co-chaperone p23.Influenza virus infection induces the nuclear relocalization of the Hsp90 co-chaperone p23 and inhibits the glucocorticoid receptor response.Distinct roles of central and peripheral prostaglandin E2 and EP subtypes in blood pressure regulationThe Aryl-hydrocarbon receptor does not require the p23 co-chaperone for ligand binding and target gene expression in vivo.Prostaglandin E2 induction during mouse adenovirus type 1 respiratory infection regulates inflammatory mediator generation but does not affect viral pathogenesis.Role of COX-2/mPGES-1/prostaglandin E2 cascade in kidney injury.COX-2 but not mPGES-1 contributes to renal PGE2 induction and diabetic proteinuria in mice with type-1 diabetes.Microsomal prostaglandin E synthase-2 is not essential for in vivo prostaglandin E2 biosynthesisCo-chaperone p23 regulates C. elegans Lifespan in Response to Temperature.A major role for the EP4 receptor in regulation of renin.Matrix metalloproteinase-dependent microsomal prostaglandin E synthase-1 expression in macrophages: role of TNF-α and the EP4 prostanoid receptor.The co-chaperone p23 promotes prostate cancer motility and metastasisProstaglandin E(2) produced by the lung augments the effector phase of allergic inflammation.p23/Sba1p protects against Hsp90 inhibitors independently of its intrinsic chaperone activityProstaglandin E(2) exerts homeostatic regulation of pulmonary vascular remodeling in allergic airway inflammation.mPGES-1 deletion impairs diuretic response to acute water loading.Genetic deletion of microsomal prostaglandin E synthase-1 suppresses mouse mammary tumor growth and angiogenesis.Prostaglandin E(2) synthase inhibition as a therapeutic target.New Insights into the PPAR γ Agonists for the Treatment of Diabetic Nephropathy.Role of PGE2 in asthma and nonasthmatic eosinophilic bronchitis.HSP90AB1: Helping the good and the bad.Identification and Characterization of Novel Microsomal Prostaglandin E Synthase-1 Inhibitors for Analgesia.COX-2 mediates PM2.5-induced apoptosis and inflammation in vascular endothelial cells.Identification of key residues determining species differences in inhibitor binding of microsomal prostaglandin E synthase-1mPGES-1 deletion potentiates urine concentrating capability after water deprivation.Prostaglandin terminal synthases as novel therapeutic targets.Gene expression changes of prostanoid synthases in endothelial cells and prostanoid receptors in vascular smooth muscle cells caused by aging and hypertension.Imbalances in the Hsp90 Chaperone Machinery: Implications for Tauopathies.Temporal expression of the PGE2 synthetic system in the kidney is associated with the time frame of renal developmental vulnerability to cyclooxygenase-2 inhibition.Minocycline reduces prostaglandin E synthase expression and 8-isoprostane formation in LPS-activated primary rat microglia.Mitochondrial oxidative stress activates COX-2/mPGES-1/PGE2 cascade induced by albumin in renal proximal tubular cells.
P2860
Q24310430-7C848FD6-7778-412C-BE22-EE14BB946E11Q24623958-45ECC6AA-A7BF-402B-B1EF-FB57F91F356FQ24629893-31A45565-0C73-47D4-B37F-0E1DCA9F50AAQ24630614-2DD808D4-116A-4B7B-9699-A4E6B392C4E0Q27011776-142E5A15-DCF8-4701-B833-22095DDB6C64Q33570060-468BF897-775F-4B32-A508-D50B13A3C997Q33720134-86E1472A-93DE-44DE-B287-30C8D53C15AAQ33751084-9BCB7695-1EC5-4F11-AE4E-7F12BCD27311Q33834774-0F17ADB8-D7F8-45A6-BA03-CE28B52EE59CQ33997127-20DE7BF2-AD6A-430E-8D0F-08A318F6E913Q34281269-70973759-B9F8-409D-9DD4-E594FDF7DF19Q34759835-EBEB1728-2192-4A15-A406-2F64E205CC98Q35023278-650B9260-7863-4F6C-8112-F4F6DCB2C912Q35097808-577FF5FF-B4F5-40C9-AF73-80F07733DB82Q35199315-D2E26EB1-41F9-46F0-9686-557321C4848DQ35238520-A5803376-759E-4F7B-BD0A-7DA6D7B10113Q35243028-B4A13286-9977-4252-BFE3-5BD2362DF4C8Q35543233-97DC569D-67C5-4311-826A-27BBAA6BE10CQ35740060-D4B644E6-F61F-4343-8D1C-D2CF4E9614F8Q35876533-D3FA4C9A-DBBC-4B5C-90B6-FFFFDD9CCAF6Q35884115-8609D1EA-2EF1-4A88-BBEF-6F2C77778102Q36710867-8F73B927-14B0-4AC5-9DBF-E382848509ACQ37040964-DAD71580-61AA-4816-8FC8-BDB7670E1B0DQ37190261-EC7A7B19-ED2F-44CE-9F6B-0C367ED5F993Q37315920-C5EBB3F0-BDC3-4078-B298-ABC5BB5802DBQ37521092-CD3448D5-7077-4188-96D3-5387300E6FBDQ37590946-2FC518BB-B6D3-4D89-8B4A-99F7349A618BQ38005107-270CA997-24E4-49AB-AFA7-6C37F9BDA682Q38584468-3E5083E2-C8C0-41BB-A644-2F9A48830DF6Q38805945-570F469D-4F3D-4A6A-8E3F-873D3E162DA7Q42059971-8B807F13-3A7A-4161-8FD8-C4A16D339764Q42427981-A05FBD7D-1003-4608-8F12-031DC5AC1B45Q42538078-BB5FA592-8112-49CB-9151-8D048B2EB7C3Q46263032-1D8FBAB9-050C-4613-ADA3-33D61B5C7155Q46868364-134C659E-31CC-4503-9412-1C46E46DFDE0Q47222377-7FE03CC1-3ECF-46AC-B398-15FB283737A7Q51785189-FF659766-0ACD-4E3C-ACBD-21DFA8351B65Q54518414-79336DFC-CA3A-431B-AF28-DE54DF3CA89EQ55024909-2F35ECE5-9A75-421B-9EFC-8E51338DA76D
P2860
cPGES/p23 is required for glucocorticoid receptor function and embryonic growth but not prostaglandin E2 synthesis
description
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im Juni 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/06/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/06/01)
@nl
наукова стаття, опублікована в червні 2007
@uk
مقالة علمية (نشرت في يونيو 2007)
@ar
name
cPGES/p23 is required for gluc ...... not prostaglandin E2 synthesis
@ast
cPGES/p23 is required for gluc ...... not prostaglandin E2 synthesis
@en
cPGES/p23 is required for gluc ...... not prostaglandin E2 synthesis
@nl
type
label
cPGES/p23 is required for gluc ...... not prostaglandin E2 synthesis
@ast
cPGES/p23 is required for gluc ...... not prostaglandin E2 synthesis
@en
cPGES/p23 is required for gluc ...... not prostaglandin E2 synthesis
@nl
prefLabel
cPGES/p23 is required for gluc ...... not prostaglandin E2 synthesis
@ast
cPGES/p23 is required for gluc ...... not prostaglandin E2 synthesis
@en
cPGES/p23 is required for gluc ...... not prostaglandin E2 synthesis
@nl
P2093
P2860
P356
P1476
cPGES/p23 is required for gluc ...... not prostaglandin E2 synthesis
@en
P2093
Alysia Kern Lovgren
Beverly H. Koller
Martina Kovarova
P2860
P304
P356
10.1128/MCB.02314-06
P407
P577
2007-06-01T00:00:00Z