SCL/Tal-1 is essential for hematopoietic commitment of the hemangioblast but not for its development
about
Concise review: programming human pluripotent stem cells into bloodStructural Basis for LMO2-Driven Recruitment of the SCL:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional TargetsThe haemangioblast generates haematopoietic cells through a haemogenic endothelium stageGeneChip analysis of human embryonic stem cell differentiation into hemangioblasts: an in silico dissection of mixed phenotypes.A mesoderm-derived precursor for mesenchymal stem and endothelial cellsNovel insights into the genetic controls of primitive and definitive hematopoiesis from zebrafish modelsDelayed differentiation in embryonic stem cells and mesodermal progenitors in the absence of CtBP2.Direct induction of haematoendothelial programs in human pluripotent stem cells by transcriptional regulators.Differential adhesion molecule expression during murine embryonic stem cell commitment to the hematopoietic and endothelial lineages.The notch ligand delta-like 4 regulates multiple stages of early hemato-vascular development.SIRT1 deficiency compromises mouse embryonic stem cell hematopoietic differentiation, and embryonic and adult hematopoiesis in the mouseA common progenitor for haematopoietic and endothelial lineages in the zebrafish gastrula.Molecular and developmental biology of the hemangioblastEctopic Runx1 expression rescues Tal-1-deficiency in the generation of primitive and definitive hematopoiesis.MiR-24 is required for hematopoietic differentiation of mouse embryonic stem cells.TAL-1/SCL and its partners E47 and LMO2 up-regulate VE-cadherin expression in endothelial cells.SCL/TAL1 regulates hematopoietic specification from human embryonic stem cells.Designer blood: creating hematopoietic lineages from embryonic stem cells.RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis.Origin and differentiation of microglia.Generation of functional hemangioblasts from human embryonic stem cells.Cooperative binding of AP-1 and TEAD4 modulates the balance between vascular smooth muscle and hemogenic cell fateHematopoietic differentiation from human ESCs as a model for developmental studies and future clinical translations. Invited review following the FEBS Anniversary Prize received on 5 July 2009 at the 34th FEBS Congress in Prague.The hemangioblast: from concept to authentication.RUNX1: A microRNA hub in normal and malignant hematopoiesis.VEGFA-dependent and -independent pathways synergise to drive Scl expression and initiate programming of the blood stem cell lineage in Xenopus.Quantitative proteomics analysis demonstrates post-transcriptional regulation of embryonic stem cell differentiation to hematopoiesis.Emerging concepts for the in vitro derivation of murine haematopoietic stem and progenitor cells.Chromatin programming by developmentally regulated transcription factors: lessons from the study of haematopoietic stem cell specification and differentiation.Diverse hematopoietic potentials of five human embryonic stem cell lines.Phosphoinositide 3-kinase signalling regulates early development and developmental haemopoiesis.Context-dependent GATA factor function: combinatorial requirements for transcriptional control in hematopoietic and endothelial cells.Mesp1 coordinately regulates cardiovascular fate restriction and epithelial-mesenchymal transition in differentiating ESCsThe balance of positive and negative effects of TGF-β signaling regulates the development of hematopoietic and endothelial progenitors in human pluripotent stem cells.Genome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells.The Flk1-Cre-mediated deletion of ETV2 defines its narrow temporal requirement during embryonic hematopoietic development.Hemangioblasts from human embryonic stem cells generate multilayered blood vessels with functional smooth muscle cells.Directed differentiation of embryonic origin-specific vascular smooth muscle subtypes from human pluripotent stem cells.Improved safety of hematopoietic transplantation with monkey embryonic stem cells in the allogeneic setting.
P2860
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P2860
SCL/Tal-1 is essential for hematopoietic commitment of the hemangioblast but not for its development
description
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Mai 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/05/15)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/05/15)
@nl
наукова стаття, опублікована в травні 2005
@uk
مقالة علمية (نشرت في 15-5-2005)
@ar
name
SCL/Tal-1 is essential for hem ...... st but not for its development
@ast
SCL/Tal-1 is essential for hem ...... st but not for its development
@en
SCL/Tal-1 is essential for hem ...... st but not for its development
@nl
type
label
SCL/Tal-1 is essential for hem ...... st but not for its development
@ast
SCL/Tal-1 is essential for hem ...... st but not for its development
@en
SCL/Tal-1 is essential for hem ...... st but not for its development
@nl
prefLabel
SCL/Tal-1 is essential for hem ...... st but not for its development
@ast
SCL/Tal-1 is essential for hem ...... st but not for its development
@en
SCL/Tal-1 is essential for hem ...... st but not for its development
@nl
P2860
P1433
P1476
SCL/Tal-1 is essential for hem ...... st but not for its development
@en
P2093
Andrew G. Elefanty
Sunita L. D'Souza
P2860
P304
P356
10.1182/BLOOD-2004-09-3611
P407
P50
P577
2005-05-15T00:00:00Z