RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis.
about
Molecular control of activation and priming in macrophagesInterplay between Transcription Factors and the Epigenome: Insight from the Role of RUNX1 in LeukemiaEpigenetic mechanisms and developmental choice hierarchies in T-lymphocyte developmentMicroglia recapitulate a hematopoietic master regulator network in the aging human frontal cortexTranscription factor-mediated reprogramming toward hematopoietic stem cellsSmall Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven CancersCoregulation of transcription factor binding and nucleosome occupancy through DNA features of mammalian enhancers.A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specificationDynamic recruitment of Ets1 to both nucleosome-occupied and -depleted enhancer regions mediates a transcriptional program switch during early T-cell differentiation.Key regulators control distinct transcriptional programmes in blood progenitor and mast cells.Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphomaConstrained transcription factor spacing is prevalent and important for transcriptional control of mouse blood cellsLymphoid to myeloid cell trans-differentiation is determined by C/EBPβ structure and post-translational modificationsEctopic Runx1 expression rescues Tal-1-deficiency in the generation of primitive and definitive hematopoiesis.Runx3-mediated transcriptional program in cytotoxic lymphocytes.A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages.Creating cellular diversity through transcription factor competitionEarly dynamic fate changes in haemogenic endothelium characterized at the single-cell level.Transcriptional control of inflammatory responses.Runx1 Transcription Factor Is Required for Myoblasts Proliferation during Muscle RegenerationIdentification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal.Repression of arterial genes in hemogenic endothelium is sufficient for haematopoietic fate acquisitionRUNX1 induces DNA replication independent of active DNA demethylation at SPI1 regulatory regions.Leukemia-Associated Cohesin Mutants Dominantly Enforce Stem Cell Programs and Impair Human Hematopoietic Progenitor Differentiation.Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation.Long and short non-coding RNAs as regulators of hematopoietic differentiationDistinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells.C/EBPβ regulates homeostatic and oncogenic gastric cell proliferationCooperative binding of AP-1 and TEAD4 modulates the balance between vascular smooth muscle and hemogenic cell fateWhy detailed model gene studies in higher eukaryotes are still necessary.RUNX1: A microRNA hub in normal and malignant hematopoiesis.A short history of hemogenic endothelium.The chromatin landscape and transcription factors in T cell programming.Hematopoietic transcriptional mechanisms: from locus-specific to genome-wide vantage points.The regulatory network of B-cell differentiation: a focused view of early B-cell factor 1 functionThe RUNX1-PU.1 axis in the control of hematopoiesis.Inducible chromatin priming is associated with the establishment of immunological memory in T cells.The role of mutations in the cohesin complex in acute myeloid leukemia.Emerging concepts for the in vitro derivation of murine haematopoietic stem and progenitor cells.Runx1 Structure and Function in Blood Cell Development.
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P2860
RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis.
@ast
RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis.
@en
RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis.
@en-gb
type
label
RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis.
@ast
RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis.
@en
RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis.
@en-gb
prefLabel
RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis.
@ast
RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis.
@en
RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis.
@en-gb
P2093
P2860
P50
P356
P1433
P1476
RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis
@en
P2093
Deborah Clarke
Dorothee Müller
Laura Noailles
Mengchu Wu
Michael Lie-A-Ling
Monika Lichtinger
Rebecca Hannah
Richard Ingram
Salam A Assi
Valerie Kouskoff
P2860
P304
P356
10.1038/EMBOJ.2012.275
P407
P50
P577
2012-10-12T00:00:00Z