R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion
about
Alpha-, Delta- and PP-cells: Are They the Architectural Cornerstones of Islet Structure and Co-ordination?Calcium release channel RyR2 regulates insulin release and glucose homeostasisCFTR is involved in the regulation of glucagon secretion in human and rodent alpha cells.Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells.Reversible changes in pancreatic islet structure and function produced by elevated blood glucose.Somatostatin receptor type 2 antagonism improves glucagon and corticosterone counterregulatory responses to hypoglycemia in streptozotocin-induced diabetic ratsA role for islet somatostatin in mediating sympathetic regulation of glucagon secretionMathematical Modeling of Interacting Glucose-Sensing Mechanisms and Electrical Activity Underlying Glucagon-Like Peptide 1 SecretionRyanodine and IP3 receptor-mediated calcium signaling play a pivotal role in neurological infrared laser modulation.SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells.Paracrine regulation of glucagon secretion: the β/α/δ model.Long-term exposure of mouse pancreatic islets to oleate or palmitate results in reduced glucose-induced somatostatin and oversecretion of glucagonRole of KATP channels in glucose-regulated glucagon secretion and impaired counterregulation in type 2 diabetes.Ca(2+) channels on the move.K(ATP) channels and islet hormone secretion: new insights and controversies.ATP-regulated potassium channels and voltage-gated calcium channels in pancreatic alpha and beta cells: similar functions but reciprocal effects on secretion.Melatonin influences somatostatin secretion from human pancreatic δ-cells via MT1 and MT2 receptors.How "Pharmacoresistant" is Cav2.3, the Major Component of Voltage-Gated R-type Ca2+ Channels?Delta cell secretory responses to insulin secretagogues are not mediated indirectly by insulin.A cullin 4B-RING E3 ligase complex fine-tunes pancreatic δ cell paracrine interactions.Membrane potential-dependent inactivation of voltage-gated ion channels in alpha-cells inhibits glucagon secretion from human islets.Pancreatic islet cells: a model for calcium-dependent peptide release.Epac2-dependent mobilization of intracellular Ca²+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in β-cells of phospholipase C-ε knockout mice.Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression.Reactive oxygen species serve as signals mediating glucose-stimulated somatostatin secretion from cultured rat gastric primary D-cells.Exocytotic properties of human pancreatic beta-cells.Autocrine activation of P2Y1 receptors couples Ca (2+) influx to Ca (2+) release in human pancreatic beta cells.Cell coupling in mouse pancreatic beta-cells measured in intact islets of Langerhans.Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men.δ-cells and β-cells are electrically coupled and regulate α-cell activity via somatostatin.The Cells of the Islets of Langerhans.TALK-1 reduces delta-cell endoplasmic reticulum and cytoplasmic calcium levels limiting somatostatin secretion.GLP-1 suppresses glucagon secretion in human pancreatic alpha-cells by inhibition of P/Q-type Ca channels
P2860
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P2860
R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion
description
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im April 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/04/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/04/01)
@nl
наукова стаття, опублікована у квітні 2007
@uk
مقالة علمية (نشرت في أبريل 2007)
@ar
name
R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion
@ast
R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion
@en
R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion
@nl
type
label
R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion
@ast
R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion
@en
R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion
@nl
prefLabel
R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion
@ast
R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion
@en
R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion
@nl
P2093
P2860
P50
P356
P1433
P1476
R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion
@en
P2093
Chris Partridge
Erik Renström
Frances M. Ashcroft
Martin Bengtsson
Matthias Braun
Paul R. V. Johnson
Quan Zhang
Sven Göpel
Toni Schneider
P2860
P2888
P304
P356
10.1038/NCB1563
P577
2007-04-01T00:00:00Z
P6179
1036575717