Molecular cloning of a pancreatic islet-specific glucose-6-phosphatase catalytic subunit-related protein
about
Human lysophosphatidylcholine acyltransferases 1 and 2 are located in lipid droplets where they catalyze the formation of phosphatidylcholineThe glucose-6-phosphatase systemG6PC3 mutations are associated with a major defect of glycosylation: a novel mechanism for neutrophil dysfunctionFoxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expressionA syndrome with congenital neutropenia and mutations in G6PC3The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetesIdentification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.Enzymatic characterization of the pancreatic islet-specific glucose-6-phosphatase-related protein (IGRP)Histidine 167 is the phosphate acceptor in glucose-6-phosphatase-beta forming a phosphohistidine enzyme intermediate during catalysisGlucose-6-phosphatase catalytic subunit gene familyCloning and characterization of the human and rat islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) genesIdentification and characterisation of a new human glucose-6-phosphatase isoformVariations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels.Moving on from GWAS: functional studies on the G6PC2 gene implicated in the regulation of fasting blood glucose.New lessons in the regulation of glucose metabolism taught by the glucose 6-phosphatase system.Multi-tissue computational modeling analyzes pathophysiology of type 2 diabetes in MKR mice.Multiple functional polymorphisms in the G6PC2 gene contribute to the association with higher fasting plasma glucose levels.The islet-specific glucose-6-phosphatase-related protein, implicated in diabetes, is a glycoprotein embedded in the endoplasmic reticulum membrane.Mapping I-A(g7) restricted epitopes in murine G6PC2.Kinetics of the post-onset decline in zinc transporter 8 autoantibodies in type 1 diabetic human subjects.Adenovirus-mediated gene therapy in a mouse model of glycogen storage disease type 1a.A pancreatic beta-cell-specific homolog of glucose-6-phosphatase emerges as a major target of cell-mediated autoimmunity in diabetesNovel stable isotope analyses demonstrate significant rates of glucose cycling in mouse pancreatic islets.Genetic and functional assessment of the role of the rs13431652-A and rs573225-A alleles in the G6PC2 promoter that are strongly associated with elevated fasting glucose levels.Islet autoantigens: structure, function, localization, and regulation.Functional Analysis of Mouse G6pc1 Mutations Using a Novel In Situ Assay for Glucose-6-Phosphatase Activity and the Effect of Mutations in Conserved Human G6PC1/G6PC2 Amino Acids on G6PC2 Protein Expression.Candidate genes for plasma triglyceride, FFA, and glucose revealed from an intercross between inbred mouse strains NZB/B1NJ and NZW/LacJG6PC2: a negative regulator of basal glucose-stimulated insulin secretionNon-antigenic and antigenic interventions in type 1 diabetesCharacterization of the mouse pancreatic islet proteome and comparative analysis with other mouse tissues.Differential regulation of islet-specific glucose-6-phosphatase catalytic subunit-related protein gene transcription by Pax-6 and Pdx-1.Meta-analyses of the association of G6PC2 allele variants with elevated fasting glucose and type 2 diabetes.Effects of G6pc2 deletion on body weight and cholesterol in mice.Upstream stimulatory factor (USF) and neurogenic differentiation/beta-cell E box transactivator 2 (NeuroD/BETA2) contribute to islet-specific glucose-6-phosphatase catalytic-subunit-related protein (IGRP) gene expression.Cytokine-induced dicing and splicing in the beta-cell and the immune response in type 1 diabetes.The three insulin response sequences in the glucose-6-phosphatase catalytic subunit gene promoter are functionally distinct.Endoplasmic reticulum stress caused by overexpression of islet-specific glucose-6-phosphatase catalytic subunit-related protein in pancreatic Beta-cells.Selective tonic inhibition of G-6-Pase catalytic subunit, but not G-6-P transporter, gene expression by insulin in vivo.Hepatic overexpression of murine Abcb11 increases hepatobiliary lipid secretion and reduces hepatic steatosis.Cloning and comparative bioinformatic analysis of feline glucose-6-phosphatase catalytic subunit cDNA.
P2860
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P2860
Molecular cloning of a pancreatic islet-specific glucose-6-phosphatase catalytic subunit-related protein
description
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1999
@ast
im März 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1999/03/01)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/03/01)
@nl
наукова стаття, опублікована в березні 1999
@uk
مقالة علمية (نشرت في مارس 1999)
@ar
name
Molecular cloning of a pancrea ...... alytic subunit-related protein
@ast
Molecular cloning of a pancrea ...... alytic subunit-related protein
@en
Molecular cloning of a pancrea ...... alytic subunit-related protein
@nl
type
label
Molecular cloning of a pancrea ...... alytic subunit-related protein
@ast
Molecular cloning of a pancrea ...... alytic subunit-related protein
@en
Molecular cloning of a pancrea ...... alytic subunit-related protein
@nl
prefLabel
Molecular cloning of a pancrea ...... alytic subunit-related protein
@ast
Molecular cloning of a pancrea ...... alytic subunit-related protein
@en
Molecular cloning of a pancrea ...... alytic subunit-related protein
@nl
P2093
P3181
P1433
P1476
Molecular cloning of a pancrea ...... alytic subunit-related protein
@en
P2093
B. Bergman
J. C. Hutton
R. M. O'Brien
S. D. Arden
S. Steegers
P304
P3181
P356
10.2337/DIABETES.48.3.531
P407
P577
1999-03-01T00:00:00Z