Multiple dose-dependent effects of Lis1 on cerebral cortical development
about
The Pafah1b complex interacts with the reelin receptor VLDLRMutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architectureCep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.The extracellular matrix, p53 and estrogen compete to regulate cell-surface Fas/Apo-1 suicide receptor expression in proliferating embryonic cerebral cortical precursors, and reciprocally, Fas-ligand modifies estrogen control of cell-cycle proteinsMicrotubule plus-end tracking proteins in neuronal developmentExtra-cell cycle regulatory functions of cyclin-dependent kinases (CDK) and CDK inhibitor proteins contribute to brain development and neurological disordersLis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells.Lis1 is necessary for normal non-radial migration of inhibitory interneuronsLIS1 RNA interference blocks neural stem cell division, morphogenesis, and motility at multiple stagesLis1-Nde1-dependent neuronal fate control determines cerebral cortical size and laminationLis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization.Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality.Hook3 interacts with PCM1 to regulate pericentriolar material assembly and the timing of neurogenesisHuman iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial GliaNeuronal migration defects in the Loa dynein mutant mouse.Advanced microscopic imaging methods to investigate cortical development and the etiology of mental retardation.Distinct dose-dependent cortical neuronal migration and neurite extension defects in Lis1 and Ndel1 mutant miceNovel embryonic neuronal migration and proliferation defects in Dcx mutant mice are exacerbated by Lis1 reduction.LIS1 controls mitosis and mitotic spindle organization via the LIS1-NDEL1-dynein complex.Identification of genes differentially expressed in dorsal and ventral chick midbrain during early developmentPlatelet activating factor blocks interkinetic nuclear migration in retinal progenitors through an arrest of the cell cycle at the S/G2 transition.The exon junction complex component Magoh controls brain size by regulating neural stem cell division.Lis1 reduction causes tangential migratory errors in mouse spinal cord.Global developmental gene expression and pathway analysis of normal brain development and mouse models of human neuronal migration defectsA three-gene expression signature model for risk stratification of patients with neuroblastomaRole of cytoskeletal abnormalities in the neuropathology and pathophysiology of type I lissencephalyGenetic mosaic dissection of Lis1 and Ndel1 in neuronal migrationAnalysis of epigenetic factors in mouse embryonic neural stem cells exposed to hyperglycemiaMiller-Dieker syndrome: analysis of a human contiguous gene syndrome in the mouse.Focusing forward genetics: a tripartite ENU screen for neurodevelopmental mutations in the mouseRegulation of cytoplasmic dynein ATPase by Lis1.GRM7 regulates embryonic neurogenesis via CREB and YAP.Recessive nephrocerebellar syndrome on the Galloway-Mowat syndrome spectrum is caused by homozygous protein-truncating mutations of WDR73.Progression from mitotic catastrophe to germ cell death in Caenorhabditis elegans lis-1 mutants requires the spindle checkpointRegulation of dynein localization and centrosome positioning by Lis-1 and asunder during Drosophila spermatogenesis.Lis1 and doublecortin function with dynein to mediate coupling of the nucleus to the centrosome in neuronal migration.Cytoskeleton in action: lissencephaly, a neuronal migration disorderNuclear migration during retinal developmentCopy Number Variations in DISC1 and DISC1-Interacting Partners in Major Mental Illness.Developmental differences of the major forebrain commissures in lissencephalies.
P2860
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P2860
Multiple dose-dependent effects of Lis1 on cerebral cortical development
description
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im März 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/03/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/03/01)
@nl
наукова стаття, опублікована в березні 2003
@uk
مقالة علمية (نشرت في مارس 2003)
@ar
name
Multiple dose-dependent effects of Lis1 on cerebral cortical development
@ast
Multiple dose-dependent effects of Lis1 on cerebral cortical development
@en
Multiple dose-dependent effects of Lis1 on cerebral cortical development
@nl
type
label
Multiple dose-dependent effects of Lis1 on cerebral cortical development
@ast
Multiple dose-dependent effects of Lis1 on cerebral cortical development
@en
Multiple dose-dependent effects of Lis1 on cerebral cortical development
@nl
prefLabel
Multiple dose-dependent effects of Lis1 on cerebral cortical development
@ast
Multiple dose-dependent effects of Lis1 on cerebral cortical development
@en
Multiple dose-dependent effects of Lis1 on cerebral cortical development
@nl
P2093
P1476
Multiple dose-dependent effects of Lis1 on cerebral cortical development
@en
P2093
Anthony Wynshaw-Boris
Dawn L Darling
Jessica Yingling
Joseph G Gleeson
Michael J Gambello
Teruyuki Tanaka
P304
P356
10.1523/JNEUROSCI.23-05-01719.2003
P407
P577
2003-03-01T00:00:00Z