Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development
about
GDF3 is a BMP inhibitor that can activate Nodal signaling only at very high dosesThe conditioned medium from a stable human GDF3-expressing CHO cell line, induces the differentiation of PC12 cellsEmerging roles of nodal and Cripto-1: from embryogenesis to breast cancer progressionNodal morphogensGrowth/differentiation factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesityMolecular specification of germ layers in vertebrate embryosActin cytoskeletal control during epithelial to mesenchymal transition: focus on the pancreas and intestinal tractA novel nodal enhancer dependent on pluripotency factors and smad2/3 signaling conditions a regulatory switch during epiblast maturationRegulation of extra-embryonic endoderm stem cell differentiation by Nodal and Cripto signalingRole of Cripto-1 in stem cell maintenance and malignant progression.Transitions between epithelial and mesenchymal states and the morphogenesis of the early mouse embryo.Activin/Nodal signalling before implantation: setting the stage for embryo patterning.Growth and differentiation factor 3 induces expression of genes related to differentiation in a model of cancer stem cells and protects them from retinoic acid-induced apoptosis.Nodal·Gdf1 heterodimers with bound prodomains enable serum-independent nodal signaling and endoderm differentiation.Growth differentiation factor 11 is an encephalic regionalizing factor in neural differentiated mouse embryonic stem cells.Cripto promotes A-P axis specification independently of its stimulatory effect on Nodal autoinduction.A role for Vg1/Nodal signaling in specification of the intermediate mesoderm.Deficiency of growth differentiation factor 3 protects against diet-induced obesity by selectively acting on white adipose.Antagonism between Smad1 and Smad2 signaling determines the site of distal visceral endoderm formation in the mouse embryo.Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease.BMP signaling in vascular development and disease.An evolving web of signaling networks regulated by Cripto-1.Developmental plasticity, cell fate specification and morphogenesis in the early mouse embryo.Analysis of the mouse embryonic stem cell regulatory networks obtained by ChIP-chip and ChIP-PETThe transcription factor Pitx2 positions the embryonic axis and regulates twinning.Cripto-1: an extracellular protein - connecting the sequestered biological dots.Gene expression analysis of bovine embryonic disc, trophoblast and parietal hypoblast at the start of gastrulation.Agonists and Antagonists of TGF-β Family Ligands.Establishment of the Vertebrate Germ Layers.GDF3 inhibits the growth of breast cancer cells and promotes the apoptosis induced by Taxol.Functional redundancy of EGF-CFC genes in epiblast and extraembryonic patterning during early mouse embryogenesis.Genome-wide detection of gene extinction in early mammalian evolution.Generation of a conditional mouse model to target Acvr1b disruption in adult tissues.Vg1-Nodal heterodimers are the endogenous inducers of mesendoderm.Gdf3 is required for robust Nodal signaling during germ layer formation and left-right patterning.Maternal Gdf3 is an obligatory cofactor in Nodal signaling for embryonic axis formation in zebrafish.Differential regulation of mouse pancreatic islet insulin secretion and Smad proteins by activin ligands.A novel variation of GDF3 in Chinese Han children with a broad phenotypic spectrum of non-syndromic CHDs.Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage PrimingPhylogenetic evidence for independent origins of GDF1 and GDF3 genes in anurans and mammals
P2860
32063d36f97e940522a5b8b98353dfc3e76228ee38d6dff7f27296f4f30f4b496acd3cda8d275bde39920b21af331fe9cebac552ba24b2994977328a489488637d290ca4fb7397d6474bbdccc9bc49286d531f30dea8d6a05c2fe74ccd27e7c2229980a86ffaa5d1956473d41b113b4b101ccd08d72882f8acd74a515898d2b52d889230aa7ca7e2d745d83dbb3893fba4c0772a6838c678357c7452c7f5a05dbb93d497ffff6f1a167792392b550d4f304e44b7c387ffbead8b97eaa9d89f3fa5f104b6361d5aff
P248
Q24317145-CDB5EFBD-E159-47B9-9DD8-1BCC50F853A4Q24318279-B0544AB8-2082-4804-85FB-2C1E355A03E1Q24635937-F2086C4A-9746-457C-B5A2-B2684D6D1345Q24644638-5E2A0C49-DE67-472C-8EF0-FF092BE22706Q24651005-E7F8C49B-6B55-4000-B305-1BAAF42F690EQ26775874-BC222457-05C5-497B-A1F5-7105E384A40BQ28082719-9D78A823-7C18-49D5-BB3D-6A6FE8D1A5F6Q28657743-0A363F3F-230B-4CC4-95D2-E15290B02FDEQ30503613-DF225279-7F7A-418A-A7F3-32799BDA31A3Q34033323-8DF44B41-756E-4C32-92E5-C26BAB93E413Q34219499-42DF12FA-39F6-4F8B-9F40-75C51C05FD4CQ34436924-BEA73DA8-94CA-45CA-8F4B-5E36E575EFDFQ34947381-FBFE6CDF-835B-436C-9E0F-73441FDDE0CBQ35163359-DAA83473-7862-422A-820D-EECBF6B7B8D3Q35373611-8F346102-267E-483E-BE76-B418C31E0CCDQ36446584-A9698586-7B28-43E6-B15F-C80A7FC4A90BQ36752969-0D6573C3-4930-43BB-8D9B-0730A51B33B9Q37106832-BF9442AB-8FCF-4D15-8707-A8DF24014E1DQ37124876-5F4D6DC4-1778-489F-84B0-A3E5302C0DF2Q37504561-3D030F00-311A-4A57-A0AA-86406E246A37Q37776859-9827D6E1-1DDD-4416-A75D-B41EFFE15CA8Q37965746-E65BD667-2DB3-4BDD-85CC-612D0861B7B7Q38263164-97060342-187B-4643-AF1C-1E3D37E619B9Q38288303-6DF83354-8185-427D-9155-61B771AF18CBQ38302265-54ABDB0C-FB84-44AC-AAD9-68E7BEEB9E7BQ38578005-866B8288-827C-4B1B-A480-2FEA7412588CQ38769455-E462B3E4-9688-4136-9BAF-07A7AA1252EEQ38896053-C1B4D508-EA59-4C9D-9BEA-9E908E391D14Q39038824-37F4D161-36BD-4CC4-9B76-C7299F751B7BQ39367312-6FC53FE3-168C-481B-A97E-551C193A2789Q40444625-081C2FA8-D089-4B1B-9369-6A75666A5C17Q42593374-4C54FA1C-949C-46A6-873D-BA54C5C17EFEQ45130114-5975F571-21C2-4C1C-832E-48688677BA6FQ47135848-4887688C-F0B5-44F3-8042-33D63BF118B8Q47160037-466265E5-C413-4563-A432-31C03DA850A1Q47417320-3D6CB1F6-091A-41A0-8F51-5D1911E169A2Q51776742-A80EEA7E-0831-4CB3-A14C-46DBFA112DD1Q54186166-94A0EA8B-8DD5-44C5-A137-2283833124A3Q58705996-57445D41-4B13-455F-A9A6-72B663E31A63Q58751843-D81AD4DB-C979-4FC9-A56B-D291FB61C98C
P2860
Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development
description
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im November 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/11/15)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/11/15)
@nl
наукова стаття, опублікована в листопаді 2007
@uk
مقالة علمية (نشرت في 15-11-2007)
@ar
name
Distinct and cooperative roles ...... ng early embryonic development
@ast
Distinct and cooperative roles ...... ng early embryonic development
@en
Distinct and cooperative roles ...... ng early embryonic development
@nl
type
label
Distinct and cooperative roles ...... ng early embryonic development
@ast
Distinct and cooperative roles ...... ng early embryonic development
@en
Distinct and cooperative roles ...... ng early embryonic development
@nl
prefLabel
Distinct and cooperative roles ...... ng early embryonic development
@ast
Distinct and cooperative roles ...... ng early embryonic development
@en
Distinct and cooperative roles ...... ng early embryonic development
@nl
P2093
P921
P1476
Distinct and cooperative roles ...... ng early embryonic development
@en
P2093
Carlos F. Ibáñez
Olov Andersson
Philippe Bertolino
P304
P356
10.1016/J.YDBIO.2007.08.060
P407
P577
2007-11-15T00:00:00Z