Identification of a new glycerol-3-phosphate acyltransferase isoenzyme, mtGPAT2, in mitochondria
about
AGPAT6 is a novel microsomal glycerol-3-phosphate acyltransferaseThematic review series: glycerolipids. Mammalian glycerol-3-phosphate acyltransferases: new genes for an old activityMolecular identification of microsomal acyl-CoA:glycerol-3-phosphate acyltransferase, a key enzyme in de novo triacylglycerol synthesisIdentification and characterization of a lysophosphatidylcholine acyltransferase in alveolar type II cellsAMPK: a cellular metabolic and redox sensor. A minireviewGlycerol-3-phosphate acyltransferases gat1p and gat2p are microsomal phosphoproteins with differential contributions to polarized cell growth.Disorders of phospholipid metabolism: an emerging class of mitochondrial disease due to defects in nuclear genesGlycerol-3-phosphate acyltransferase-1 regulates murine T-lymphocyte proliferation and cytokine productionMice deficient in mitochondrial glycerol-3-phosphate acyltransferase-1 have diminished myocardial triacylglycerol accumulation during lipogenic diet and altered phospholipid fatty acid compositionAltering the Mitochondrial Fatty Acid Synthesis (mtFASII) Pathway Modulates Cellular Metabolic States and Bioactive Lipid Profiles as Revealed by Metabolomic ProfilingIncreased mitochondrial glycerol-3-phosphate acyltransferase protein and enzyme activity in rat epididymal fat upon cessation of wheel runningThe lipid droplet coat protein perilipin 5 also localizes to muscle mitochondriaMitochondrial glycerol-3-P acyltransferase 1 is most active in outer mitochondrial membrane but not in mitochondrial associated vesicles (MAV)Cloning and functional characterization of a novel mitochondrial N-ethylmaleimide-sensitive glycerol-3-phosphate acyltransferase (GPAT2)SEIPIN Regulates Lipid Droplet Expansion and Adipocyte Development by Modulating the Activity of Glycerol-3-phosphate AcyltransferaseRegulation of Triglyceride Metabolism. II. Function of mitochondrial GPAT1 in the regulation of triacylglycerol biosynthesis and insulin actionHepatic overexpression of glycerol-sn-3-phosphate acyltransferase 1 in rats causes insulin resistance.How do I fatten thee? Let me count the ways...Identification of a novel sn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient in Agpat6-/- mice.Glycerol-3-phosphate acyltransferase-2 is expressed in spermatic germ cells and incorporates arachidonic acid into triacylglycerolsEnzymatic activities of the human AGPAT isoform 3 and isoform 5: localization of AGPAT5 to mitochondria.Anthocyanin inhibits high glucose-induced hepatic mtGPAT1 activation and prevents fatty acid synthesis through PKCζ.Glycerophosphate/Acylglycerophosphate acyltransferases.Pharmacological glycerol-3-phosphate acyltransferase inhibition decreases food intake and adiposity and increases insulin sensitivity in diet-induced obesity.Mammalian triacylglycerol metabolism: synthesis, lipolysis, and signalingDesign and synthesis of small molecule glycerol 3-phosphate acyltransferase inhibitors.Glycerol-3-phosphate Acyltransferase Isoform-4 (GPAT4) Limits Oxidation of Exogenous Fatty Acids in Brown AdipocytesIncreased oxidative stress is associated with balanced increases in hepatocyte apoptosis and proliferation in glycerol-3-phosphate acyltransferase-1 deficient mice.AMP-activated protein kinase--the fat controller of the energy railroad.Mice deficient in glycerol-3-phosphate acyltransferase-1 have a reduced susceptibility to liver cancerMitochondria-type GPAT is required for mitochondrial fusionThe microsomal cardiolipin remodeling enzyme acyl-CoA lysocardiolipin acyltransferase is an acyltransferase of multiple anionic lysophospholipids.Biochemistry, physiology, and genetics of GPAT, AGPAT, and lipin enzymes in triglyceride synthesis.Glycerol-3-phosphate acyltransferases: rate limiting enzymes of triacylglycerol biosynthesis.Triacylglycerol metabolism in adipose tissue.Design, synthesis, and biological evaluation of conformationally constrained glycerol 3-phosphate acyltransferase inhibitors.Is hepatic lipogenesis fundamental for NAFLD/NASH? A focus on the nuclear receptor coactivator PGC-1β.Regulation of de novo phosphatidylinositol synthesis.GPAT3 and GPAT4 are regulated by insulin-stimulated phosphorylation and play distinct roles in adipogenesisHydrophobic-domain-dependent protein-protein interactions mediate the localization of GPAT enzymes to ER subdomains.
P2860
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P2860
Identification of a new glycerol-3-phosphate acyltransferase isoenzyme, mtGPAT2, in mitochondria
description
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2004
@ast
im April 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/04/02)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/04/02)
@nl
наукова стаття, опублікована у квітні 2004
@uk
name
Identification of a new glycer ...... zyme, mtGPAT2, in mitochondria
@ast
Identification of a new glycer ...... zyme, mtGPAT2, in mitochondria
@en
Identification of a new glycer ...... zyme, mtGPAT2, in mitochondria
@nl
type
label
Identification of a new glycer ...... zyme, mtGPAT2, in mitochondria
@ast
Identification of a new glycer ...... zyme, mtGPAT2, in mitochondria
@en
Identification of a new glycer ...... zyme, mtGPAT2, in mitochondria
@nl
prefLabel
Identification of a new glycer ...... zyme, mtGPAT2, in mitochondria
@ast
Identification of a new glycer ...... zyme, mtGPAT2, in mitochondria
@en
Identification of a new glycer ...... zyme, mtGPAT2, in mitochondria
@nl
P2093
P356
P1476
Identification of a new glycer ...... zyme, mtGPAT2, in mitochondria
@en
P2093
Douglas P. Lee
Nicole M. J. Schwerbrock
Rosalind A. Coleman
Tal M. Lewin
P304
13488–13495
P356
10.1074/JBC.M314032200
P407
P577
2004-04-02T00:00:00Z