Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis - Wikidata - awgldk - TriplyDB

Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis

Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis

http://www.wikidata.org/entity/Q28590770

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Association and regulation of casein kinase 2 activity by adenomatous polyposis coli protein Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic intervention Group IVA Cytosolic Phospholipase A2 Regulates the G2-to-M Transition by Modulating the Activity of Tumor Suppressor SIRT2.Phospholipid remodeling and eicosanoid signaling in colon cancer cells COX-2 and cancer: a new approach to an old problem Pathogenesis of colorectal carcinoma and therapeutic implications: the roles of the ubiquitin-proteasome system and Cox-2 Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88 Inherited human cPLA(2alpha) deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction.Distinct role of Kruppel-like factor 11 in the regulation of prostaglandin E2 biosynthesis.Impacts of cytosolic phospholipase A2, 15-prostaglandin dehydrogenase, and cyclooxygenase-2 expressions on tumor progression in colorectal cancer.The COXes of Danio: from mechanistic model to experimental therapeutics.Potential role of microsomal prostaglandin E synthase-1 in tumorigenesis.Phospholipase A2 group IIA expression in gastric adenocarcinoma is associated with prolonged survival and less frequent metastasis.Targeting cytosolic phospholipase A2 α in colorectal cancer cells inhibits constitutively activated protein kinase B (AKT) and cell proliferation.Cytosolic phospholipase A(2)α protects against ischemia/reperfusion injury in the heart.The RNA-binding protein HuR stabilizes cytosolic phospholipase A2α mRNA under interleukin-1β treatment in non-small cell lung cancer A549 Cells Chemical strategies for activity-based proteomics.Cytosolic phospholipase A₂: physiological function and role in disease.Lysophosphatidic acid facilitates proliferation of colon cancer cells via induction of Krüppel-like factor 5.Discrete role for cytosolic phospholipase A(2)alpha in platelets: studies using single and double mutant mice of cytosolic and group IIA secretory phospholipase A(2).Sarcophine-diol inhibits expression of COX-2, inhibits activity of cPLA2, enhances degradation of PLA2 and PLC(γ)1 and inhibits cell membrane permeability in mouse melanoma B16F10 cells.Cytosolic phospholipase A2α regulates G1 progression through modulating FOXO1 activity Multistep carcinogenesis of the colon in Apc(Min/+) mouse.Roles of cPLA2alpha and arachidonic acid in cancer Synthesis and Evaluation of Cytosolic Phospholipase A(2) Activatable Fluorophores for Cancer Imaging.Characterization of eicosanoid synthesis in a genetic ablation model of ceramide kinase Cytosolic phospholipase A2-alpha: a potential therapeutic target for prostate cancer Low molecular weight hyaluronan activates cytosolic phospholipase A2α and eicosanoid production in monocytes and macrophages.Implication of ceramide, ceramide 1-phosphate and sphingosine 1-phosphate in tumorigenesis.Multifaceted roles of PGE2 in inflammation and cancer.Transforming growth factor-beta (TGF-beta) activates cytosolic phospholipase A2alpha (cPLA2alpha)-mediated prostaglandin E2 (PGE)2/EP1 and peroxisome proliferator-activated receptor-gamma (PPAR-gamma)/Smad signaling pathways in human liver cancer ce Prognostic significance of cytosolic phospholipase A2 expression in patients with colorectal cancer Endogenous lipid hydroperoxide-mediated DNA-adduct formation in min mice.Activation of cPLA2 is required for leukotriene D4-induced proliferation in colon cancer cells.Mitochondria are direct targets of the lipoxygenase inhibitor MK886. A strategy for cell killing by combined treatment with MK886 and cyclooxygenase inhibitors.Leukotriene B4-receptor-1 mediated host response shapes gut microbiota and controls colon tumor progression.The yin and yang of leukotriene B4 mediated inflammation in cancer.Phospholipid Remodeling and Cholesterol Availability Regulate Intestinal Stemness and Tumorigenesis.Nrf2 knockout enhances intestinal tumorigenesis in Apc(min/+) mice due to attenuation of anti-oxidative stress pathway while potentiates inflammation.

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Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis

http://www.wikidata.org/entity/Q28590770

description

2001 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի մարտին հրատարակված գիտական հոդված

@hy

article publié dans les Procee ...... f the United States of America

@fr

artículu científicu espublizáu en 2001

@ast

im März 2001 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2001/03/27)

@sk

vědecký článek publikovaný v roce 2001

@cs

wetenschappelijk artikel (gepubliceerd op 2001/03/27)

@nl

наукова стаття, опублікована в березні 2001

@uk

name

Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis

@ast

Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis

@en

Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis

@nl

type

label

Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis

@ast

Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis

@en

Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis

@nl

prefLabel

Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis

@ast

Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis

@en

Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis

@nl

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis

@en

P2093

E. O'Leary

http://www.w3.org/2001/XMLSchema#string

E. S. Lander

http://www.w3.org/2001/XMLSchema#string

J. C. Bonventre

http://www.w3.org/2001/XMLSchema#string

J. V. Bonventre

http://www.w3.org/2001/XMLSchema#string

K. H. Hong

http://www.w3.org/2001/XMLSchema#string

P2860

Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene

Relationship of beta-catenin and Bcl-2 expression to sulindac-induced regression of intestinal tumors in Min mice

Role of the prostaglandin E receptor subtype EP1 in colon carcinogenesis

The Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system

Suppression of intestinal polyposis in Apc(delta 716) knockout mice by an additional mutation in the cytosolic phospholipase A(2) gene

Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)

Secretory phospholipase Pla2g2a confers resistance to intestinal tumorigenesis

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

Simplified mammalian DNA isolation procedure

The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia.

P304

3935–3939

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scholarly article

P356

10.1073/PNAS.051635898

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P407

P433

7

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P478

98

http://www.w3.org/2001/XMLSchema#string

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2001-03-27T00:00:00Z

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P5875

12059544

http://www.w3.org/2001/XMLSchema#string

P698

11274413

http://www.w3.org/2001/XMLSchema#string

P921

Adenomatous polyposis coli protein

P932

31157

http://www.w3.org/2001/XMLSchema#string