Mitochondria are direct targets of the lipoxygenase inhibitor MK886. A strategy for cell killing by combined treatment with MK886 and cyclooxygenase inhibitors.
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Enhanced formation of 5-oxo-6,8,11,14-eicosatetraenoic acid by cancer cells in response to oxidative stress, docosahexaenoic acid and neutrophil-derived 5-hydroxy-6,8,11,14-eicosatetraenoic acidThe mitochondrial fission protein hFis1 requires the endoplasmic reticulum gateway to induce apoptosisThe mitochondrial effects of small organic ligands of BCL-2: sensitization of BCL-2-overexpressing cells to apoptosis by a pyrimidine-2,4,6-trione derivative.Effect of leukotriene inhibitors on evolution of experimental brain contusions.Down-regulation of vinculin upon MK886-induced apoptosis in LN18 glioblastoma cellsEarly resistance to cell death and to onset of the mitochondrial permeability transition during hepatocarcinogenesis with 2-acetylaminofluorene.Roles of cPLA2alpha and arachidonic acid in cancerPitfalls in the use of arachidonic acid oxidation products to assign lipoxygenase activity in cancer cells.Overexpression of cytosolic group IVA phospholipase A2 protects cells from Ca2+-dependent death.Up-regulation of cyclooxygenase-2 and apoptosis resistance by p38 MAPK in hypericin-mediated photodynamic therapy of human cancer cells.Mitochondrial disorders in NSAIDs-induced small bowel injury.Increased expression of the lipocalin 24p3 as an apoptotic mechanism for MK886.Arachidonic acid released by phospholipase A(2) activation triggers Ca(2+)-dependent apoptosis through the mitochondrial pathway.Acetylsalicylic acid-tris-hydroxymethyl-aminomethane reduces colon mucosal damage without causing gastric side effects in a rat model of colitis.Overexpression of 5-lipoxygenase and its relation with cell proliferation and angiogenesis in 7,12-dimethylbenz(α)anthracene-induced rat mammary carcinogenesis.Modulation of hypericin photodynamic therapy by pretreatment with 12 various inhibitors of arachidonic acid metabolism in colon adenocarcinoma HT-29 cells.
P2860
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P2860
Mitochondria are direct targets of the lipoxygenase inhibitor MK886. A strategy for cell killing by combined treatment with MK886 and cyclooxygenase inhibitors.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Mitochondria are direct target ...... and cyclooxygenase inhibitors.
@en
type
label
Mitochondria are direct target ...... and cyclooxygenase inhibitors.
@en
prefLabel
Mitochondria are direct target ...... and cyclooxygenase inhibitors.
@en
P2093
P2860
P50
P356
P1476
Mitochondria are direct target ...... and cyclooxygenase inhibitors.
@en
P2093
Arianna Gugliucci
Claudia Cusan
Francesco Pagano
Laura Ranzato
Mariangela Mancini
Raffaele Colonna
P2860
P304
31789-31795
P356
10.1074/JBC.M204450200
P407
P577
2002-06-21T00:00:00Z