Neonatal lethality associated with respiratory distress in mice lacking cytochrome P450 1A2
about
Xenobiotic-metabolizing cytochrome P450 enzymes in the human feto-placental unit: role in intrauterine toxicityCharacterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and developmentCyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolismDifferential regulation of hepatic cytochrome P450 monooxygenases in streptozotocin-induced diabetic ratsA comprehensive investigation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) metabolism in the mouse using a multivariate data analysis approach.Cytochrome P450-null mice.The lung HETEs (and EETs) up.Using cytochrome P-450 gene knock-out mice to study chemical metabolism, toxicity, and carcinogenicity.Drug-metabolizing enzyme, transporter, and nuclear receptor genetically modified mouse models.Understanding the mechanisms of infant respiratory distress and chronic lung disease.Use of genetically engineered mice in drug discovery and development: wielding Occam's razor to prune the product portfolio.Metabolic activation of toxins: tissue-specific expression and metabolism in target organs.Urinary metabolite profiling reveals CYP1A2-mediated metabolism of NSC686288 (aminoflavone).Role of gene knockout and transgenic mice in the study of xenobiotic metabolism.Hyalinosis and Ym1/Ym2 gene expression in the stomach and respiratory tract of 129S4/SvJae and wild-type and CYP1A2-null B6, 129 mice.Sheep lung cytochrome P4501A1 (CYP1A1): cDNA cloning and transcriptional regulation by oxygen tension.Abnormal liver development and resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in mice carrying a mutation in the DNA-binding domain of the aryl hydrocarbon receptor.PhRMA white paper on ADME pharmacogenomics.Transgenic animals in toxicology.Cytochrome P450 knockout mice: new toxicological models.Use of transgenic animals in understanding molecular mechanisms of toxicity.Emerging issues in mouse liver carcinogenesis.Ecogenetics: from ecology to health.The hepatic reductase null mouse as a model for exploring hepatic conjugation of xenobiotics: application to the metabolism of diclofenac.
P2860
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P2860
Neonatal lethality associated with respiratory distress in mice lacking cytochrome P450 1A2
description
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 1995
@ast
im Mai 1995 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1995/05/23)
@sk
vědecký článek publikovaný v roce 1995
@cs
wetenschappelijk artikel (gepubliceerd op 1995/05/23)
@nl
наукова стаття, опублікована в травні 1995
@uk
name
Neonatal lethality associated ...... ce lacking cytochrome P450 1A2
@ast
Neonatal lethality associated ...... ce lacking cytochrome P450 1A2
@en
Neonatal lethality associated ...... ce lacking cytochrome P450 1A2
@nl
type
label
Neonatal lethality associated ...... ce lacking cytochrome P450 1A2
@ast
Neonatal lethality associated ...... ce lacking cytochrome P450 1A2
@en
Neonatal lethality associated ...... ce lacking cytochrome P450 1A2
@nl
prefLabel
Neonatal lethality associated ...... ce lacking cytochrome P450 1A2
@ast
Neonatal lethality associated ...... ce lacking cytochrome P450 1A2
@en
Neonatal lethality associated ...... ce lacking cytochrome P450 1A2
@nl
P2093
P2860
P356
P1476
Neonatal lethality associated ...... ce lacking cytochrome P450 1A2
@en
P2093
F. J. Gonzalez
J. M. Ward
P. Fernandez-Salguero
T. McPhail
P2860
P304
P356
10.1073/PNAS.92.11.5134
P407
P577
1995-05-23T00:00:00Z