Disruption of G protein-coupled receptor 39 impairs insulin secretion in vivo
about
GPR39 is coupled to TMEM16A in intestinal fibroblast-like cellsG protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunctionThe diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearanceGPR39 marks specific cells within the sebaceous gland and contributes to skin wound healingChemical Probe Identification Platform for Orphan GPCRs Using Focused Compound Screening: GPR39 as a Case Example.The hungry stomach: physiology, disease, and drug development opportunities.Novel Zn2+ Modulated GPR39 Receptor Agonists Do Not Drive Acute Insulin Secretion in Rodents.Nor-1, a novel incretin-responsive regulator of insulin genes and insulin secretion.GPR39 receptors and actions of trace metals on pancreatic beta cell function and glucose homoeostasis.Protein kinase inhibitor β enhances the constitutive activity of G-protein-coupled zinc receptor GPR39.GPR39-1b, the 5-transmembrane isoform of GPR39 interacts with neurotensin receptor NTSR1 and modifies its function.β-Cell Specific Overexpression of GPR39 Protects against Streptozotocin-Induced HyperglycemiaThe Gq/G11-mediated signaling pathway is critical for autocrine potentiation of insulin secretion in miceDiscovery of 2-Pyridylpyrimidines as the First Orally Bioavailable GPR39 Agonists.Bis(hinokitiolato)zinc complex ([Zn(hkt)2]) activates Akt/protein kinase B independent of insulin signal transduction.Target identification for a Hedgehog pathway inhibitor reveals the receptor GPR39.The Zinc Sensing Receptor, ZnR/GPR39, in Health and Disease.Changes in obestatin gene and GPR39 receptor expression in peripheral tissues of rat models of obesity, type 1 and type 2 diabetes.
P2860
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P2860
Disruption of G protein-coupled receptor 39 impairs insulin secretion in vivo
description
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im Juni 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/06/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/06/01)
@nl
наукова стаття, опублікована в червні 2009
@uk
مقالة علمية (نشرت في يونيو 2009)
@ar
name
Disruption of G protein-coupled receptor 39 impairs insulin secretion in vivo
@ast
Disruption of G protein-coupled receptor 39 impairs insulin secretion in vivo
@en
Disruption of G protein-coupled receptor 39 impairs insulin secretion in vivo
@nl
type
label
Disruption of G protein-coupled receptor 39 impairs insulin secretion in vivo
@ast
Disruption of G protein-coupled receptor 39 impairs insulin secretion in vivo
@en
Disruption of G protein-coupled receptor 39 impairs insulin secretion in vivo
@nl
prefLabel
Disruption of G protein-coupled receptor 39 impairs insulin secretion in vivo
@ast
Disruption of G protein-coupled receptor 39 impairs insulin secretion in vivo
@en
Disruption of G protein-coupled receptor 39 impairs insulin secretion in vivo
@nl
P2093
P921
P356
P1433
P1476
Disruption of G protein-coupled receptor 39 impairs insulin secretion in vivo
@en
P2093
Ann-Marie T. Richard
Frédéric Tremblay
Jameel Syed
Mylène Perreault
Nancy Stedman
Ruth E. Gimeno
Sarah Will
P304
P356
10.1210/EN.2008-1251
P407
P577
2009-06-01T00:00:00Z