The HIF family member EPAS1/HIF-2alpha is required for normal hematopoiesis in mice
about
Mammalian tumor suppressor Int6 specifically targets hypoxia inducible factor 2 alpha for degradation by hypoxia- and pVHL-independent regulationA family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasisHypoxic regulation of erythropoiesis and iron metabolismA gain-of-function mutation in the HIF2A gene in familial erythrocytosisIron-regulatory proteins limit hypoxia-inducible factor-2alpha expression in iron deficiencyNovel functional view of the crocidolite asbestos-treated A549 human lung epithelial transcriptome reveals an intricate network of pathways with opposing functionsModulation of membrane lipid composition and homeostasis in salmon hepatocytes exposed to hypoxia and perfluorooctane sulfonamide, given singly or in combinationAcute postnatal ablation of Hif-2alpha results in anemiaEndoglin integrates BMP and Wnt signalling to induce haematopoiesis through JDP2.Functional genomics approach to hypoxia signaling.Hypoxia regulates BMP4 expression in the murine spleen during the recovery from acute anemia.EPAS1 gene variants are associated with sprint/power athletic performance in two cohorts of European athletes.Hypoxia, HIF, and Associated Signaling Networks in Chronic Kidney Disease.Noninvasive stool-based detection of infant gastrointestinal development using gene expression profiles from exfoliated epithelial cells.An acetate switch regulates stress erythropoiesis.HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth.Oxygen-Dependent Gene Expression in Development and Cancer: Lessons Learned from the Wilms' Tumor Gene, WT1Two functional loci in the promoter of EPAS1 gene involved in high-altitude adaptation of Tibetans.Intermittent exposure to xenon protects against gentamicin-induced nephrotoxicity.Hypoxia increases sirtuin 1 expression in a hypoxia-inducible factor-dependent manner.Energy status and HIF signalling in chorionic villi show no evidence of hypoxic stress during human early placental development.Hypoxia-inducible factor as an angiogenic master switchThe aryl hydrocarbon receptor nuclear translocator is an essential regulator of murine hematopoietic stem cell viability.The Human Blood Metabolome-Transcriptome InterfaceAnaemia in kidney disease: harnessing hypoxia responses for therapyA 3.4-kb Copy-Number Deletion near EPAS1 Is Significantly Enriched in High-Altitude Tibetans but Absent from the Denisovan Sequence.Hypoxia and HIFs in regulating the development of the hematopoietic system.VHL: oxygen sensing and vasculogenesis.Hypoxia-inducible factor as a physiological regulator.Metabolic reprogramming and two-compartment tumor metabolism: opposing role(s) of HIF1α and HIF2α in tumor-associated fibroblasts and human breast cancer cellsMeis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cellsRegulation of adult erythropoiesis by prolyl hydroxylase domain proteinsCanonical Wnt signaling in megakaryocytes regulates proplatelet formation.Notch1 is required for hypoxia-induced proliferation, invasion and chemoresistance of T-cell acute lymphoblastic leukemia cells.Dysregulated angiogenesis in B-chronic lymphocytic leukemia: morphologic, immunohistochemical, and flow cytometric evidence.Autocrine VEGF loops, signaling pathways, and acute leukemia regulation.Regulation of erythropoiesis by hypoxia-inducible factorsBiology of hypoxia-inducible factor-2alpha in development and diseaseAutophagy in mineralizing tissues: microenvironmental perspectives.Role of hypoxia and HIF2α in development of the sympathoadrenal cell lineage and chromaffin cell tumors with distinct catecholamine phenotypic features.
P2860
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P2860
The HIF family member EPAS1/HIF-2alpha is required for normal hematopoiesis in mice
description
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im September 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/09/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/09/01)
@nl
наукова стаття, опублікована у вересні 2003
@uk
مقالة علمية (نشرت في سبتمبر 2003)
@ar
name
The HIF family member EPAS1/HIF-2alpha is required for normal hematopoiesis in mice
@ast
The HIF family member EPAS1/HIF-2alpha is required for normal hematopoiesis in mice
@en
The HIF family member EPAS1/HIF-2alpha is required for normal hematopoiesis in mice
@nl
type
label
The HIF family member EPAS1/HIF-2alpha is required for normal hematopoiesis in mice
@ast
The HIF family member EPAS1/HIF-2alpha is required for normal hematopoiesis in mice
@en
The HIF family member EPAS1/HIF-2alpha is required for normal hematopoiesis in mice
@nl
prefLabel
The HIF family member EPAS1/HIF-2alpha is required for normal hematopoiesis in mice
@ast
The HIF family member EPAS1/HIF-2alpha is required for normal hematopoiesis in mice
@en
The HIF family member EPAS1/HIF-2alpha is required for normal hematopoiesis in mice
@nl
P2093
P3181
P1433
P1476
The HIF family member EPAS1/HIF-2alpha is required for normal hematopoiesis in mice
@en
P2093
Joseph A. Garcia
Margaret A. Morris
Marzia Scortegagna
Michael Bennett
Yavuz Oktay
P304
P3181
P356
10.1182/BLOOD-2003-02-0448
P407
P577
2003-09-01T00:00:00Z