Defective T cell development and function in calcineurin A beta -deficient mice
about
Calcineurin/nuclear factors of activated T cells (NFAT)-activating and immunoreceptor tyrosine-based activation motif (ITAM)-containing protein (CNAIP), a novel ITAM-containing protein that activates the calcineurin/NFAT-signaling pathwayTOX provides a link between calcineurin activation and CD8 lineage commitmentLessons learned from gene expression profiling of cutaneous T-cell lymphomaNFAT proteins: key regulators of T-cell development and functionModulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivoBcl11b is required for differentiation and survival of alphabeta T lymphocytesNFATc1 regulates lymphatic endothelial developmentHeart-specific deletion of CnB1 reveals multiple mechanisms whereby calcineurin regulates cardiac growth and function.Digital NFATc2 activation per cell transforms graded T cell receptor activation into an all-or-none IL-2 expression.Ubc9 Is Required for Positive Selection and Late-Stage Maturation of Thymocytes.Calcium signaling in immune cells.PKCtheta is necessary for efficient activation of NFkappaB, NFAT, and AP-1 during positive selection of thymocytes.Tenuous paths in unexplored territory: From T cell receptor signaling to effector gene expression during thymocyte selection.Meeting of the minds: metalloneurochemistryThe role of calcium/calmodulin-activated calcineurin in rapid and slow endocytosis at central synapses.Neoplastic transformation of T lymphocytes through transgenic expression of a virus host modification protein.Everolimus for the treatment of uveitis refractory to cyclosporine A: a pilot study.Nutritional intervention restores muscle but not kidney phenotypes in adult calcineurin Aα null mice.The β isoform of the catalytic subunit of protein phosphatase 2B restrains platelet function by suppressing outside-in αII b β3 integrin signaling.Rescue of calcineurin Aα(-/-) mice reveals a novel role for the α isoform in the salivary gland.Altered skeletal muscle phenotypes in calcineurin Aalpha and Abeta gene-targeted miceCalcineurin A-alpha but not A-beta is required for normal kidney development and functionTherapeutic potential of macrolide immunosuppressants in dermatology.Pharmacological and genetic inhibition of calcineurin protects against carbachol-induced pathological zymogen activation and acinar cell injury.Exposure to Radiocontrast Agents Induces Pancreatic Inflammation by Activation of Nuclear Factor-κB, Calcium Signaling, and Calcineurin.Commitment issues: linking positive selection signals and lineage diversification in the thymus.An emerging role for calcineurin Aalpha in the development and function of the kidney.Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterasesCa2+-operated transcriptional networks: molecular mechanisms and in vivo models.TGF-beta upregulation drives tertiary lymphoid organ formation and kidney dysfunction in calcineurin A-alpha heterozygous mice.Calmodulin-dependent phosphatase, kinases, and transcriptional corepressors involved in T-cell activationPancreatic acinar cell nuclear factor κB activation because of bile acid exposure is dependent on calcineurin.Differential requirement of PKC-theta in the development and function of natural regulatory T cells.Chronic exercise downregulates myocardial myoglobin and attenuates nitrite reductase capacity during ischemia-reperfusion.The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cellsThe calcium/NFAT pathway: role in development and function of regulatory T cells.Can proliferation signal inhibitor-induced Tregs really reflect transplantation tolerance in clinical solid organ transplantation?Novel inhibitors of the calcineurin/NFATc hub - alternatives to CsA and FK506?Molecular and genetic parameters defining T-cell clonal selection.Calcineurin inhibitors and immunosuppression - a tale of two isoforms.
P2860
Q24296746-351DE163-736D-4AB4-BE7E-96A3930B9886Q24647569-475A28C4-C0E3-434A-94D0-7573F8BD92CDQ26865858-7FE72D7A-0C6F-4AD2-AFCF-0CE2E470A98AQ28253919-AC04F813-3253-4C9C-B5CB-BA48488EB12CQ28505205-207FD06B-0BBD-4A1B-A0AA-B93AC3A5814DQ28592191-37CB9D80-072A-499E-9199-7D460D30407DQ28593523-AEA78D9C-0503-423F-A1EC-C9F04863CA93Q30493276-B4915A12-53D7-444D-9256-A7A88A75D954Q33300337-E94A925B-24C3-4D01-BAED-B294E126C15EQ33567980-41CDFAC9-D453-4C25-B079-C43F39A4D8FDQ33878792-B18D0EEB-5408-4AE8-826C-BCFAD7D19E0FQ34118353-D2C07D39-B63D-452A-A036-90A7802487A1Q34137305-86209C29-F4FA-493B-8FED-4F476A3C9D2EQ34185781-180A6C04-7113-4125-9897-6CCA6C6AA341Q34196522-DDFDB8F4-9400-4C4F-90DA-39EB63CC1C19Q34256167-E355DDBE-C822-4953-8FE3-4C26A44D3A05Q34449084-AE5EFE66-CF9A-477A-BD11-D5D98977A0A2Q34701648-ADE801D4-F961-480C-8552-2C7B4CAC3469Q34717790-8EF4FEAE-8464-448C-8007-FB90329C21B4Q34805437-666C4CFF-F828-462F-8E8F-B7FBF5DD4966Q35019954-F440908F-9A92-4BA2-8DC5-E019ECDB753BQ35103375-AAE92A16-040B-40B0-9274-8C590195EA4CQ35680649-70A82FC5-7CEE-46B6-9BA0-889E57219C5BQ35970173-73EEA64E-0993-49CF-83B6-554E69D56EF7Q35998360-2688C0C4-F26A-4E44-B18B-74128AD1223AQ36382781-B7ADD6D8-6923-4F78-B48A-DEACC6C6AE4AQ36417660-DD785327-7876-46D8-B558-1CF004B7023CQ36579585-E18E30B5-ECC6-4B4F-B76F-98DF6EC48FD7Q37129336-9675B224-F6A8-4F71-8837-9DE539EBA183Q37138821-DF17A086-6B0E-49EE-B1FB-FCF9C6A99A77Q37160059-7B26B1A6-F5F5-41CA-9780-A10D3FC05F23Q37175126-9523BF69-661B-4CEF-9C5D-8CB6415FA20EQ37236962-0A9AAB14-9814-443E-8AB9-6B7E0590A702Q37238807-959F0805-880A-45E1-9294-816DEEEF47D3Q37310026-9953625E-708B-43A8-A355-C40D7BC56653Q37449706-866E30ED-D2C0-4532-9C7F-C0E2D42BEDADQ37610445-1B4D8A28-171E-497B-8804-F0CE17DD7F24Q37622487-27F9B000-6491-4808-A0F8-5C37980AC983Q37801270-CA109C4D-FB81-4F43-B4E8-B6553E1B1190Q38027011-F74A75A0-7656-4713-8FCB-F804A55F40AD
P2860
Defective T cell development and function in calcineurin A beta -deficient mice
description
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2002
@ast
im Juli 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/07/09)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/07/09)
@nl
наукова стаття, опублікована в липні 2002
@uk
name
Defective T cell development and function in calcineurin A beta -deficient mice
@ast
Defective T cell development and function in calcineurin A beta -deficient mice
@en
Defective T cell development and function in calcineurin A beta -deficient mice
@nl
type
label
Defective T cell development and function in calcineurin A beta -deficient mice
@ast
Defective T cell development and function in calcineurin A beta -deficient mice
@en
Defective T cell development and function in calcineurin A beta -deficient mice
@nl
prefLabel
Defective T cell development and function in calcineurin A beta -deficient mice
@ast
Defective T cell development and function in calcineurin A beta -deficient mice
@en
Defective T cell development and function in calcineurin A beta -deficient mice
@nl
P2093
P2860
P921
P356
P1476
Defective T cell development and function in calcineurin A beta -deficient mice
@en
P2093
Jeffery D. Molkentin
Marc E. Rothenberg
Orlando F. Bueno
P2860
P304
P356
10.1073/PNAS.152665399
P407
P577
2002-07-09T00:00:00Z