JNK is required for effector T-cell function but not for T-cell activation
about
Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2.MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokinesMEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cellsRole of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cellsSchnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cellsThe stressed synoviumInhibitors of mitogen-activated protein kinases differentially regulate costimulated T cell cytokine production and mouse airway eosinophilia.Redox regulation of T-cell function: from molecular mechanisms to significance in human health and diseaseA RING to rule them all? Insights into the Map3k1 PHD motif provide a new mechanistic understanding into the diverse roles of Map3k1ICOS co-stimulatory receptor is essential for T-cell activation and functionjkk-1 and mek-1 regulate body movement coordination and response to heavy metals through jnk-1 in Caenorhabditis elegansMAPK signaling in inflammation-associated cancer developmentRequirement of the JIP1 scaffold protein for stress-induced JNK activationJun kinase delays caspase-9 activation by interaction with the apoptosomeDeficiency of small GTPase Rac2 affects T cell activationRegulation of mature T lymphocyte proliferation and differentiation by Par-4Defective T cell development and function in calcineurin A beta -deficient miceRegulation of innate and adaptive immune responses by MAP kinase phosphatase 5Structural determinants for the biological activity of Vav proteins.Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease.c-Jun NH2-terminal kinase is required for lineage-specific differentiation but not stem cell self-renewal.Effect of doublecortin on self-renewal and differentiation in brain tumor stem cells.c-Jun N-terminal kinase activation in Xenopus laevis eggs and embryos. A possible non-genomic role for the JNK signaling pathway.Inhibition of effector function but not T cell activation and increase in FoxP3 expression in T cells differentiated in the presence of PP14.Mixed Lineage Kinase 3 deficiency delays viral clearance in the lung and is associated with diminished influenza-induced cytopathic effect in infected cellsRBP4 activates antigen-presenting cells, leading to adipose tissue inflammation and systemic insulin resistance.CARMA1-mediated NF-kappaB and JNK activation in lymphocytes.Wnt4 enhances murine hematopoietic progenitor cell expansion through a planar cell polarity-like pathwaySingle-cell analysis of signal transduction in CD4 T cells stimulated by antigen in vivoSignal transduction by MAP kinases in T lymphocytes.Vav-Rac1-mediated activation of the c-Jun N-terminal kinase/c-Jun/AP-1 pathway plays a major role in stimulation of the distal NFAT site in the interleukin-2 gene promoterReview article: molecular signals and genetic reprogramming in peripheral T-cell differentiation.Jun N-terminal kinase 2 modulates thymocyte apoptosis and T cell activation through c-Jun and nuclear factor of activated T cell (NF-AT)Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo.Partners in transcription: NFAT and AP-1.Control of T helper cell differentiation--in search of master genes.Convergence of Itch-induced ubiquitination with MEKK1-JNK signaling in Th2 tolerance and airway inflammation.Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational changeT-cell regulation by CD28 and CTLA-4.Suppression of p53-dependent senescence by the JNK signal transduction pathway
P2860
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P2860
JNK is required for effector T-cell function but not for T-cell activation
description
2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 2000
@ast
scientific journal article
@en
vedecký článok (publikovaný 2000/05/04)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/05/04)
@nl
наукова стаття, опублікована в травні 2000
@uk
مقالة علمية (نشرت في 4-5-2000)
@ar
name
JNK is required for effector T-cell function but not for T-cell activation
@ast
JNK is required for effector T-cell function but not for T-cell activation
@en
JNK is required for effector T-cell function but not for T-cell activation
@nl
type
label
JNK is required for effector T-cell function but not for T-cell activation
@ast
JNK is required for effector T-cell function but not for T-cell activation
@en
JNK is required for effector T-cell function but not for T-cell activation
@nl
prefLabel
JNK is required for effector T-cell function but not for T-cell activation
@ast
JNK is required for effector T-cell function but not for T-cell activation
@en
JNK is required for effector T-cell function but not for T-cell activation
@nl
P2093
P3181
P356
P1433
P1476
JNK is required for effector T-cell function but not for T-cell activation
@en
P2093
A. J. Whitmarsh
C. Tournier
D. D. Yang
R. A. Flavell
R. J. Davis
P2888
P3181
P356
10.1038/35011091
P407
P577
2000-05-04T00:00:00Z
P6179
1018609726