Characterization of murine A-raf, a new oncogene related to the v-raf oncogene - Wikidata - awgldk - TriplyDB

Characterization of murine A-raf, a new oncogene related to the v-raf oncogene

Characterization of murine A-raf, a new oncogene related to the v-raf oncogene

http://www.wikidata.org/entity/Q28592226

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The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-raf carrying retrovirus Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor-mediated differentiation Dynamic changes in C-Raf phosphorylation and 14-3-3 protein binding in response to growth factor stimulation: differential roles of 14-3-3 protein binding sites Regulation of RAF activity by 14-3-3 proteins: RAF kinases associate functionally with both homo- and heterodimeric forms of 14-3-3 proteins B-raf oncogene: activation by rearrangements and assignment to human chromosome 7 RASSF1A and NORE1A methylation and BRAFV600E mutations in thyroid tumors Forebrain-specific knockout of B-raf kinase leads to deficits in hippocampal long-term potentiation, learning, and memory Cortical migration defects in mice expressing A-RAF from the B-RAF locus Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells Biochemical Analysis of MEK Activation in NIH3T3 Fibroblasts Mutational activation of c-raf-1 and definition of the minimal transforming sequence.Both p21ras and pp60v-src are required, but neither alone is sufficient, to activate the Raf-1 kinase Genetic screens in mammalian cells by enhanced retroviral mutagens.Molecular organization of the human Raf-1 promoter region.Development of a highly efficient expression cDNA cloning system: application to oncogene isolation.An altered v-raf is required in addition to v-myc in J3V1 virus for acceleration of murine plasmacytomagenesis.Differential effects on cAMP on the MAP kinase cascade: evidence for a cAMP-insensitive step that can bypass Raf-1 Unique N-region determines low basal activity and limited inducibility of A-RAF kinase: the role of N-region in the evolutionary divergence of RAF kinase function in vertebrates.Detection of BRAF(V600E) Mutations in Papillary Thyroid Carcinomas by Peptide Nucleic Acid Clamp Real-Time PCR: A Comparison with Direct Sequencing Raf kinases: oncogenesis and drug discovery.Raf-1 protein kinase activates the NF-kappa B transcription factor by dissociating the cytoplasmic NF-kappa B-I kappa B complex.Expression of raf oncogenes activates the PEA1 transcription factor motif Mapping by in vitro constructs of the P100gag-mil region, accounting for induction of chicken neuroretina cell proliferation Mouse map of paralogous genes.Insertional oncogenesis by non-acute retroviruses: implications for gene therapy.BRAF and MEK gene rearrangements in melanoma: implications for targeted therapy.Expression of the Raf-1 protein in rat brain during development and its hormonal regulation in hypothalamus.Receptor systems in tissues of the nervous system.Tyr phosphatase-mediated P-ERK inhibition suppresses senescence in EIA + v-raf transformed cells, which, paradoxically, are apoptosis-protected in a MEK-dependent manner DA-Raf1, a competent intrinsic dominant-negative antagonist of the Ras-ERK pathway, is required for myogenic differentiation.Mutational analysis of the ARAF gene in human cancers.ERK signalling and oncogene transformation are not impaired in cells lacking A-Raf.Nuclear import of protein kinases and cyclins.A common cellular pathway for v-mos and v-Ki-ras is not required for v-Ki-ras-induced tumorigenicity in a nonmalignant, v-mos-expressing revertant cell.Single substitution within the RKTR motif impairs kinase activity but promotes dimerization of RAF kinase.The genesis of Zelboraf: targeting mutant B-Raf in melanoma.Phorbol ester stimulates the synthesis of sphingomyelin in NIH 3T3 cells. A diminished response in cells transformed with human A-raf carrying retrovirus.Positive regulation of A-RAF by phosphorylation of isoform-specific hinge segment and identification of novel phosphorylation sites.Disruption of the 14-3-3 binding site within the B-Raf kinase domain uncouples catalytic activity from PC12 cell differentiation.Expression of mixed lineage kinase-1 in pancreatic beta-cell lines at different stages of maturation and during embryonic pancreas development.

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Characterization of murine A-raf, a new oncogene related to the v-raf oncogene

http://www.wikidata.org/entity/Q28592226

description

1986 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

1986 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 1986

@ast

im Juli 1986 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 1986/07/01)

@sk

vědecký článek publikovaný v roce 1986

@cs

wetenschappelijk artikel (gepubliceerd op 1986/07/01)

@nl

наукова стаття, опублікована в липні 1986

@uk

مقالة علمية (نشرت في يوليو 1986)

@ar

name

Characterization of murine A-raf, a new oncogene related to the v-raf oncogene

@ast

Characterization of murine A-raf, a new oncogene related to the v-raf oncogene

@en

Characterization of murine A-raf, a new oncogene related to the v-raf oncogene

@nl

type

label

Characterization of murine A-raf, a new oncogene related to the v-raf oncogene

@ast

Characterization of murine A-raf, a new oncogene related to the v-raf oncogene

@en

Characterization of murine A-raf, a new oncogene related to the v-raf oncogene

@nl

prefLabel

Characterization of murine A-raf, a new oncogene related to the v-raf oncogene

@ast

Characterization of murine A-raf, a new oncogene related to the v-raf oncogene

@en

Characterization of murine A-raf, a new oncogene related to the v-raf oncogene

@nl

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Molecular and Cellular Biology

P1476

Characterization of murine A-raf, a new oncogene related to the v-raf oncogene

@en

P2093

J. Cleveland

http://www.w3.org/2001/XMLSchema#string

M. Goldsborough

http://www.w3.org/2001/XMLSchema#string

M. Gunnell

http://www.w3.org/2001/XMLSchema#string

M. Huleihel

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T. Bonner

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U. R. Rapp

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P2860

DNA sequencing with chain-terminating inhibitors

Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose

Primary structure of v-raf: relatedness to the src family of oncogenes

Nucleotide sequence of avian retroviral oncogene v-mil: homologue of murine retroviral oncogene v-raf

Serine- and threonine-specific protein kinase activities of purified gag-mil and gag-raf proteins

Structure and activation of the human N-ras gene

The human homologs of the raf (mil) oncogene are located on human chromosomes 3 and 4

Amino terminal myristylation of the protein kinase p60src, a retroviral transforming protein

Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

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2655–2662

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scholarly article

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10.1128/MCB.6.7.2655

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7

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3491291

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367822

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