Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus
about
Dynamic changes in C-Raf phosphorylation and 14-3-3 protein binding in response to growth factor stimulation: differential roles of 14-3-3 protein binding sitesSecond nature: biological functions of the Raf-1 "kinase"IQGAP1 modulates activation of B-RafRaf family kinases: old dogs have learned new tricksRegulation of RAF activity by 14-3-3 proteins: RAF kinases associate functionally with both homo- and heterodimeric forms of 14-3-3 proteins3pK, a novel mitogen-activated protein (MAP) kinase-activated protein kinase, is targeted by three MAP kinase pathwaysAutoregulation of the Raf-1 serine/threonine kinaseConstitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosisTargeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyondThe Crystal Structure of BRAF in Complex with an Organoruthenium Inhibitor Reveals a Mechanism for Inhibition of an Active Form of BRAF KinaseRegulation of Raf through phosphorylation and N terminus-C terminus interactionRaf kinases in cancer-roles and therapeutic opportunitiesB-raf oncogene: activation by rearrangements and assignment to human chromosome 7Association rate constants of ras-effector interactions are evolutionarily conservedComparison of peptide array substrate phosphorylation of c-Raf and mitogen activated protein kinase kinase kinase 8Cortical migration defects in mice expressing A-RAF from the B-RAF locusIn vitro and in vivo antitumor activity of a novel semisynthetic derivative of cucurbitacin BHepatic epidermal growth factor-regulated mitogen-activated protein kinase kinase kinase activity in the rat: lack of identity with known forms of raf and MEKKCharacterization of murine A-raf, a new oncogene related to the v-raf oncogeneMutagenesis of avian carcinoma virus MH2: only one of two potential transforming genes (delta gag-myc) transforms fibroblastsAdvanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell lineRas history: The saga continues.Mutational activation of c-raf-1 and definition of the minimal transforming sequence.Raf-1 is a potential substrate for mitogen-activated protein kinase in vivo.Requirement for Raf and MAP kinase function during the meiotic maturation of Xenopus oocytesBoth p21ras and pp60v-src are required, but neither alone is sufficient, to activate the Raf-1 kinaseRAF kinase activity regulates neuroepithelial cell proliferation and neuronal progenitor cell differentiation during early inner ear development.Genetic screens in mammalian cells by enhanced retroviral mutagens.C-Raf deficiency leads to hearing loss and increased noise susceptibility.How Genetics Has Helped Piece Together the MAPK Signaling Pathway.A-RAF kinase functions in ARF6 regulated endocytic membrane traffic.Expression of cellular protooncogenes in the mouse male germ line: a distinctive 2.4-kilobase pim-1 transcript is expressed in haploid postmeiotic cellsMalignant transformation by ras and other oncogenes produces common alterations in inositol phospholipid signaling pathwaysIn vitro-derived leukemic erythroid cell lines induced by a raf- and myc-containing retrovirus differentiate in response to erythropoietinSignal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity.Genetic and cytogenetic localisation of the homeo box containing genes on mouse chromosome 6 and human chromosome 7.Integration of transfected LTR sequences into the c-raf proto-oncogene: activation by promoter insertionRAS Interaction with PI3K: More Than Just Another Effector PathwayA brief history of melanoma: from mummies to mutationsAn altered v-raf is required in addition to v-myc in J3V1 virus for acceleration of murine plasmacytomagenesis.
P2860
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P2860
Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus
description
1983 nî lūn-bûn
@nan
1983 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1983 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1983年の論文
@ja
1983年論文
@yue
1983年論文
@zh-hant
1983年論文
@zh-hk
1983年論文
@zh-mo
1983年論文
@zh-tw
1983年论文
@wuu
name
Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus
@ast
Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus
@en
Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus
@nl
type
label
Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus
@ast
Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus
@en
Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus
@nl
prefLabel
Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus
@ast
Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus
@en
Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus
@nl
P2093
P2860
P356
P1476
Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus
@en
P2093
F H Reynolds
J R Stephenson
M D Goldsborough
T I Bonner
P2860
P304
P356
10.1073/PNAS.80.14.4218
P407
P577
1983-07-01T00:00:00Z