Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice
about
Genes that regulate morphogenesis and growth of the temporomandibular joint: a reviewShox2 is required for the proper development of the facial motor nucleus and the establishment of the facial nervesTemporomandibular joint formation requires two distinct hedgehog-dependent stepsSHOX2 is a direct miR-375 target and a novel epithelial-to-mesenchymal transition inducer in breast cancer cellsBMPRIA mediated signaling is essential for temporomandibular joint development in mice.Current concepts in the pathogenesis of traumatic temporomandibular joint ankylosisMice with an anterior cleft of the palate survive neonatal lethality.Functional redundancy between human SHOX and mouse Shox2 genes in the regulation of sinoatrial node formation and pacemaking function.Altered FGF Signaling Pathways Impair Cell Proliferation and Elevation of Palate Shelves.Spry1 and spry2 are essential for development of the temporomandibular jointA common Shox2-Nkx2-5 antagonistic mechanism primes the pacemaker cell fate in the pulmonary vein myocardium and sinoatrial node.Overexpression of Indian hedgehog partially rescues short stature homeobox 2-overexpression-associated congenital dysplasia of the temporomandibular joint in mice.Gene Mutations Associated with Temporomandibular Joint Disorders: A Systematic Review.Observing the development of the temporomandibular joint in embryonic and post-natal mice using various staining methods.Shox2 is a molecular determinant of depot-specific adipocyte function.A Track Record on SHOX: From Basic Research to Complex Models and TherapyShox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5.Expressing human SHOX in Shox2SHOX KI/KI mice leads to congenital osteoarthritis‑like disease of the temporomandibular joint in postnatal mice.RNA sequencing (RNA-Seq) of lymph node, spleen, and thymus transcriptome from wild Peninsular Malaysian cynomolgus macaque (Macaca fascicularis).Mouse genetic models for temporomandibular joint development and disordersTissue interaction is required for glenoid fossa development during temporomandibular joint formation.In vivo loss of function study reveals the short stature homeobox-containing (shox) gene plays indispensable roles in early embryonic growth and bone formation in zebrafish.Generation of Shox2-Cre allele for tissue specific manipulation of genes in the developing heart, palate, and limb.Overexpression of Shox2 leads to congenital dysplasia of the temporomandibular joint in mice.Replacing Shox2 with human SHOX leads to congenital disc degeneration of the temporomandibular joint in mice.Augmented Indian hedgehog signaling in cranial neural crest cells leads to craniofacial abnormalities and dysplastic temporomandibular joint in mice.Specific inactivation of Twist1 in the mandibular arch neural crest cells affects the development of the ramus and reveals interactions with hand2.Indian hedgehog roles in post-natal TMJ development and organizationThe role of Shox2 in SAN development and function.A Joint Less Ordinary: Intriguing Roles for Hedgehog Signalling in the Development of the Temporomandibular Synovial Joint.
P2860
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P2860
Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice
description
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im August 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/08/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/08/01)
@nl
наукова стаття, опублікована в серпні 2008
@uk
مقالة علمية (نشرت في أغسطس 2008)
@ar
name
Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice
@ast
Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice
@en
Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice
@nl
type
label
Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice
@ast
Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice
@en
Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice
@nl
prefLabel
Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice
@ast
Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice
@en
Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice
@nl
P2093
P2860
P3181
P1476
Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice
@en
P2093
P2860
P304
P3181
P356
10.1016/J.MOD.2008.04.003
P577
2008-08-01T00:00:00Z