Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules
about
The PH domain proteins IPIP27A and B link OCRL1 to receptor recycling in the endocytic pathwayDent Disease with mutations in OCRL1Diversity of Cl(-) channelsOCRL1 function in renal epithelial membrane trafficFrom bowel to kidneys: the role of cubilin in physiology and diseaseProtein trafficking defects in inherited kidney diseasesThe fast-recycling receptor Megalin defines the apical recycling pathway of epithelial cells.Tubular proteinuria in mice and humans lacking the intrinsic lysosomal protein SCARB2/Limp-2The inositol Inpp5k 5-phosphatase affects osmoregulation through the vasopressin-aquaporin 2 pathway in the collecting systemNHE3 Na+/H+ exchanger supports proximal tubular protein reabsorption in vivoGenome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes.Mimicry of a host anion channel by a Helicobacter pylori pore-forming toxin.Renal phenotype in Lowe Syndrome: a selective proximal tubular dysfunctionCLC-5 and KIF3B interact to facilitate CLC-5 plasma membrane expression, endocytosis, and microtubular transport: relevance to pathophysiology of Dent's disease.CFTR and TNR-CFTR expression and function in the kidney.Time course of pathogenic and adaptation mechanisms in cystinotic mouse kidneysZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells.Role of ClC-5 in renal endocytosis is unique among ClC exchangers and does not require PY-motif-dependent ubiquitylation.Diabetic rats present higher urinary loss of proteins and lower renal expression of megalin, cubilin, ClC-5, and CFTR.Apolipoprotein M modulates erythrocyte efflux and tubular reabsorption of sphingosine-1-phosphate.Anti-inflammatory effects of tetradecylthioacetic acid (TTA) in macrophage-like cells from Atlantic salmon (Salmo salar L.).Hereditary causes of kidney stones and chronic kidney diseaseChloride channels of intracellular membranesCofilin interacts with ClC-5 and regulates albumin uptake in proximal tubule cell lines.Dent's disease.Cadmium impairs albumin reabsorption by down-regulating megalin and ClC5 channels in renal proximal tubule cells.Renal vacuolar H+-ATPase.Nedd4-2 functionally interacts with ClC-5: involvement in constitutive albumin endocytosis in proximal tubule cells.The kidney in vitamin B12 and folate homeostasis: characterization of receptors for tubular uptake of vitamins and carrier proteins.A primary culture of mouse proximal tubular cells, established on collagen-coated membranes.Proximal tubule endocytic apparatus as the specific renal uptake mechanism for vitamin D-binding protein/25-(OH)D3 complex.Mouse model for Lowe syndrome/Dent Disease 2 renal tubulopathy.MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.Chloride channel (Clc)-5 is necessary for exocytic trafficking of Na+/H+ exchanger 3 (NHE3).Immunoglobulin light chains activate tubular epithelial cells through redox signaling.The Lowe syndrome protein OCRL1 is required for endocytosis in the zebrafish pronephric tubule.Clcn5 knockout mice exhibit novel immunomodulatory effects and are more susceptible to dextran sulfate sodium-induced colitis.Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells.Proteomic strategies and their application in studies of renal function.Molecular changes in proximal tubule function in diabetes mellitus.
P2860
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P2860
Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules
description
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2003
@ast
im Juli 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/07/08)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/07/08)
@nl
наукова стаття, опублікована в липні 2003
@uk
name
Loss of chloride channel ClC-5 ...... lin in kidney proximal tubules
@ast
Loss of chloride channel ClC-5 ...... lin in kidney proximal tubules
@en
Loss of chloride channel ClC-5 ...... lin in kidney proximal tubules
@nl
type
label
Loss of chloride channel ClC-5 ...... lin in kidney proximal tubules
@ast
Loss of chloride channel ClC-5 ...... lin in kidney proximal tubules
@en
Loss of chloride channel ClC-5 ...... lin in kidney proximal tubules
@nl
prefLabel
Loss of chloride channel ClC-5 ...... lin in kidney proximal tubules
@ast
Loss of chloride channel ClC-5 ...... lin in kidney proximal tubules
@en
Loss of chloride channel ClC-5 ...... lin in kidney proximal tubules
@nl
P2093
P2860
P921
P3181
P356
P1476
Loss of chloride channel ClC-5 ...... lin in kidney proximal tubules
@en
P2093
Erik I. Christensen
Geneviève Dom
Michèle Leruth
Patrick Van der Smissen
Pierre J. Courtoy
Pierre Verroust
Rikke Nielsen
William B. Guggino
P2860
P304
P3181
P356
10.1073/PNAS.1432873100
P407
P577
2003-07-08T00:00:00Z