Primary structure, tissue distribution, and expression of mouse phosphoinositide-dependent protein kinase-1, a protein kinase that phosphorylates and activates protein kinase Czeta
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Phosphorylation of protein kinase N by phosphoinositide-dependent protein kinase-1 mediates insulin signals to the actin cytoskeletonSubstitution of a glycogen synthase kinase-3beta phosphorylation site in presenilin 1 separates presenilin function from beta-catenin signalingIdentification of a pocket in the PDK1 kinase domain that interacts with PIF and the C-terminal residues of PKAProtein kinase C iota: human oncogene, prognostic marker and therapeutic targetPerspectives in PDK1 evolution: insights from photosynthetic and non-photosynthetic organismsSli2 (Ypk1), a homologue of mammalian protein kinase SGK, is a downstream kinase in the sphingolipid-mediated signaling pathway of yeast.A 3-phosphoinositide-dependent protein kinase-1 (PDK1) docking site is required for the phosphorylation of protein kinase Czeta (PKCzeta ) and PKC-related kinase 2 by PDK1Inhibition of insulin-induced activation of Akt by a kinase-deficient mutant of the epsilon isozyme of protein kinase CExpression cloning of protein targets for 3-phosphorylated phosphoinositidesTyrosine phosphorylation of phosphoinositide-dependent kinase 1 by the insulin receptor is necessary for insulin metabolic signalingCross-talk between protein kinases Czeta and B in cyclic AMP-mediated sodium taurocholate co-transporting polypeptide translocation in hepatocytesMembrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and atypical protein kinase C but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes.3-phosphoinositide-dependent protein kinase 1, an Akt1 kinase, is involved in dephosphorylation of Thr-308 of Akt1 in Chinese hamster ovary cells.PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle.Nuclear translocation of 3'-phosphoinositide-dependent protein kinase 1 (PDK-1): a potential regulatory mechanism for PDK-1 function.Modulation of cellular apoptotic potential: contributions to oncogenesis.Natural biology of polyomavirus middle T antigen.PDK1 regulates growth through Akt and S6K in Drosophila.Regulation of motility of myogenic cells in filling limb muscle anlagen by Pitx2.Transduction of growth or mitogenic signals into translational activation of TOP mRNAs is fully reliant on the phosphatidylinositol 3-kinase-mediated pathway but requires neither S6K1 nor rpS6 phosphorylationInflammation, kidney function and albuminuria in the Framingham Offspring cohort.Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions.Association of PKCζ expression with clinicopathological characteristics of breast cancer.APPL1 mediates adiponectin-induced LKB1 cytosolic localization through the PP2A-PKCzeta signaling pathwayMolecular mechanisms of the diabetogenic effects of arsenic: inhibition of insulin signaling by arsenite and methylarsonous acid.Insulino-mimetic and anti-diabetic effects of vanadium compounds.Phosphoinositide dependent protein kinase 1 is required for exercise-induced cardiac hypertrophy but not the associated mitochondrial adaptations.Genetics of melanomaAdiponectin activates AMP-activated protein kinase in muscle cells via APPL1/LKB1-dependent and phospholipase C/Ca2+/Ca2+/calmodulin-dependent protein kinase kinase-dependent pathways.Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.PDK1 controls upstream PI3K expression and PIP3 generation.Protein kinase C theta (PKCtheta)-dependent phosphorylation of PDK1 at Ser504 and Ser532 contributes to palmitate-induced insulin resistance.Fine tuning PDK1 activity by phosphorylation at Ser163.Characterization of testis-specific serine-threonine kinase 3 and its activation by phosphoinositide-dependent kinase-1-dependent signalling.Atypical protein kinase Ciota plays a critical role in human lung cancer cell growth and tumorigenicity.Dual regulation of glycogen synthase kinase-3beta by the alpha1A-adrenergic receptor.Disruption of 3-phosphoinositide-dependent kinase 1 (PDK1) signaling by the anti-tumorigenic and anti-proliferative agent n-alpha-tosyl-l-phenylalanyl chloromethyl ketone.Insulin activates protein kinases C-zeta and C-lambda by an autophosphorylation-dependent mechanism and stimulates their translocation to GLUT4 vesicles and other membrane fractions in rat adipocytes.p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1).Role of PDK1 in insulin-signaling pathway for glucose metabolism in 3T3-L1 adipocytes.
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P2860
Primary structure, tissue distribution, and expression of mouse phosphoinositide-dependent protein kinase-1, a protein kinase that phosphorylates and activates protein kinase Czeta
description
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1999
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im März 1999 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 1999/03/19)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/03/19)
@nl
наукова стаття, опублікована в березні 1999
@uk
name
Primary structure, tissue dist ...... activates protein kinase Czeta
@ast
Primary structure, tissue dist ...... activates protein kinase Czeta
@en
Primary structure, tissue dist ...... activates protein kinase Czeta
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type
label
Primary structure, tissue dist ...... activates protein kinase Czeta
@ast
Primary structure, tissue dist ...... activates protein kinase Czeta
@en
Primary structure, tissue dist ...... activates protein kinase Czeta
@nl
prefLabel
Primary structure, tissue dist ...... activates protein kinase Czeta
@ast
Primary structure, tissue dist ...... activates protein kinase Czeta
@en
Primary structure, tissue dist ...... activates protein kinase Czeta
@nl
P2093
P2860
P356
P1476
Primary structure, tissue dist ...... activates protein kinase Czeta
@en
P2093
L. Q. Dong
P. Langlais
R. B. Zhang
P2860
P304
P356
10.1074/JBC.274.12.8117
P407
P577
1999-03-19T00:00:00Z