Growth retardation, early death, and DNA repair defects in mice deficient for the nucleotide excision repair enzyme XPF
about
SIRT6 in DNA repair, metabolism and ageingFirst reported patient with human ERCC1 deficiency has cerebro-oculo-facio-skeletal syndrome with a mild defect in nucleotide excision repair and severe developmental failureGenome Instability in Development and Aging: Insights from Nucleotide Excision Repair in Humans, Mice, and WormsModeling the study of DNA damage responses in miceDiseases associated with defective responses to DNA damageDNA repair endonuclease ERCC1-XPF as a novel therapeutic target to overcome chemoresistance in cancer therapyCell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiencyAdaptive stress response in segmental progeria resembles long-lived dwarfism and calorie restriction in micePhysiological consequences of defects in ERCC1-XPF DNA repair endonucleaseThe ERCC1/XPF endonuclease is required for efficient single-strand annealing and gene conversion in mammalian cellsERCC1-XPF endonuclease facilitates DNA double-strand break repairMutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemiaMalfunction of nuclease ERCC1-XPF results in diverse clinical manifestations and causes Cockayne syndrome, xeroderma pigmentosum, and Fanconi anemiaDeletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctionsThe Cerebro-oculo-facio-skeletal Syndrome Point Mutation F231L in the ERCC1 DNA Repair Protein Causes Dissociation of the ERCC1-XPF ComplexThe XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways.Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome.An Xpb mouse model for combined xeroderma pigmentosum and cockayne syndrome reveals progeroid features upon further attenuation of DNA repair.ERCC1/XPF protects short telomeres from homologous recombination in Arabidopsis thaliana.Repair of laser-localized DNA interstrand cross-links in G1 phase mammalian cellsCharacterization of Brca2-deficient plants excludes the role of NHEJ and SSA in the meiotic chromosomal defect phenotype.Drosophila ERCC1 is required for a subset of MEI-9-dependent meiotic crossoversMultiple DNA binding domains mediate the function of the ERCC1-XPF protein in nucleotide excision repair.Deficiency in the nuclease activity of xeroderma pigmentosum G in mice leads to hypersensitivity to UV irradiation.Structure-specific endonucleases xpf and mus81 play overlapping but essential roles in DNA repair by homologous recombination.Association between single nucleotide polymorphisms in ERCC4 and risk of squamous cell carcinoma of the head and neckIncreased meiotic crossovers and reduced genome stability in absence of Schizosaccharomyces pombe Rad16 (XPF).Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instabilityERCC1/XPF limits L1 retrotranspositionALKBH1 is dispensable for abasic site cleavage during base excision repair and class switch recombination.Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway.A mouse model of accelerated liver aging caused by a defect in DNA repairThe ERCC1 and ERCC4 (XPF) genes and gene productsComparison of mice with accelerated aging caused by distinct mechanismsExtended longevity mechanisms in short-lived progeroid mice: identification of a preservative stress response associated with successful aging.Nucleotide excision repair in an immunoglobulin variable gene is less efficient than in a housekeeping gene.Fluorescence-based incision assay for human XPF-ERCC1 activity identifies important elements of DNA junction recognition.Comparison of ERCC1/XPF genetic variation, mRNA and protein levels in women with advanced stage ovarian cancer treated with intraperitoneal platinum.DNA-damage repair; the good, the bad, and the ugly.A metabolic signature predicts biological age in mice.
P2860
Q24653962-E4DF1388-7F92-4346-9707-E6686F62AC7FQ24680149-098BC622-E641-4E0C-AD74-6F885BD3917AQ26796574-3966605F-45A3-4C2B-99AD-316ECBB36AFBQ26826949-7431DFF6-2B76-449E-9660-231466F00757Q26997852-BA134C13-B4B7-4B52-B92C-0990F3E4887CQ27022940-C2F623F6-6DD8-476B-9AC3-417C5BDFE3E3Q27312602-1F29BC8F-9155-4FB9-B92D-FBDEBB93C2C7Q27315126-89F274D5-620D-4A6D-B8B3-4FCE825EFEECQ28238547-B582A472-9AFB-4F3D-A7E6-CABC3DEB5DACQ28254892-31283013-5A34-4995-B04C-19CA2D072721Q28283273-C53FE70F-E916-42C4-8BFF-2E82DCAAB820Q28289720-87AAF927-EBB5-4113-B416-84AF3E5E8AB1Q28289730-0163072C-773B-4839-9F32-137DED05AE4AQ28508643-22F35E5D-E104-4742-A3E3-4CCDBCC42535Q29542538-4307CCD3-6982-4884-B211-630BEECDCFCFQ30919478-440C3F4B-709A-411C-ACF3-309828B0526CQ33275830-CB6E7FCC-2CD1-471C-A662-72ED6E9C7343Q33396433-D61A9FF7-B445-4568-A916-BE6C316FD737Q33408764-4D14C511-6F29-436C-9939-4D4D2D811679Q33493863-B8013846-D341-48B3-B714-B5D360B10D05Q34062584-DFCEBAF6-3300-43EE-B19C-68AC6DEA4D80Q34081683-A98A194E-5145-414C-97D4-A51E7C499F22Q34252316-F8525255-72C9-42B2-A71F-8EAF757FC537Q34302249-518CC53A-F8DC-47F0-945A-42CF65B607CCQ34338526-ED3ADDBF-6AF3-496D-A9C5-5CFA510BD644Q34359175-0AF7F8BA-E0D6-4219-BEC4-F181D6264643Q34636209-A6F9A3E9-265D-4BB9-9912-7A540F97937EQ34747176-291460D6-CA79-40F1-8122-3AA99A2310A6Q34768580-77B1DE53-9B21-49E6-AA91-2199939821C2Q34794942-69BE8931-CAA4-427C-BA4D-11DBD9A696E2Q34835796-63C7AF79-8521-48EF-B45A-71DF469182C1Q35649150-2B01481D-A303-4CC8-8FC6-1AAF223DF45CQ35663361-BDDD56ED-BB87-4889-8910-F310CD0868C9Q35732338-A379A796-7FC1-4AAE-9E92-EF980FA2E039Q35891561-F3333058-4089-4F82-8125-E2D1EE202EF8Q35902286-31C3B745-C14F-489A-B26D-704C55145EF6Q36107000-A01125FF-DBF9-4290-B33E-F50497CC738AQ36457582-FC89E417-FCA1-4968-9191-942A23F632EAQ36487307-4DF1AAD7-C49F-4FA2-98A1-16BC7CDCA69EQ36553679-E647629D-6EB0-4AFA-A7CD-9350EC2B5810
P2860
Growth retardation, early death, and DNA repair defects in mice deficient for the nucleotide excision repair enzyme XPF
description
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Februar 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/02/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/02/01)
@nl
наукова стаття, опублікована в лютому 2004
@uk
مقالة علمية (نشرت في فبراير 2004)
@ar
name
Growth retardation, early deat ...... ide excision repair enzyme XPF
@ast
Growth retardation, early deat ...... ide excision repair enzyme XPF
@en
Growth retardation, early deat ...... ide excision repair enzyme XPF
@nl
type
label
Growth retardation, early deat ...... ide excision repair enzyme XPF
@ast
Growth retardation, early deat ...... ide excision repair enzyme XPF
@en
Growth retardation, early deat ...... ide excision repair enzyme XPF
@nl
prefLabel
Growth retardation, early deat ...... ide excision repair enzyme XPF
@ast
Growth retardation, early deat ...... ide excision repair enzyme XPF
@en
Growth retardation, early deat ...... ide excision repair enzyme XPF
@nl
P2093
P2860
P1476
Growth retardation, early deat ...... ide excision repair enzyme XPF
@en
P2093
Frederick W. Alt
Nobuhiko Shinkura
Reiko Shinkura
P2860
P304
P356
10.1128/MCB.24.3.1200-1205.2004
P407
P577
2004-02-01T00:00:00Z