Enterohepatic circulation of bile salts in farnesoid X receptor-deficient mice: efficient intestinal bile salt absorption in the absence of ileal bile acid-binding protein
about
Chronic diarrhea due to excessive bile acid synthesis and not defective ileal transport: a new syndrome of defective fibroblast growth factor 19 releaseEndocrine fibroblast growth factors 15/19 and 21: from feast to famineBile acid transportersBile acid binding protein: a versatile host of small hydrophobic ligands for applications in the fields of MRI contrast agents and bio-nanomaterialsHepatic farnesoid X-receptor isoforms α2 and α4 differentially modulate bile salt and lipoprotein metabolism in miceRegulation of fibroblast growth factor 15/19 and 21 on metabolism: in the fed or fasted stateBile acid signaling in metabolic disease and drug therapyIleal bile acid-binding protein, functionally associated with the farnesoid X receptor or the ileal bile acid transporter, regulates bile acid activity in the small intestineRole of the intestinal bile acid transporters in bile acid and drug dispositionThe farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in miceFarnesoid X Receptor an Emerging Target to Combat Obesity.Chronic intermittent psychological stress promotes macrophage reverse cholesterol transport by impairing bile acid absorption in mice.Ageing Fxr deficient mice develop increased energy expenditure, improved glucose control and liver damage resembling NASHBile acid-induced elevated oxidative stress in the absence of farnesoid X receptor.Proteomics for the discovery of nuclear bile acid receptor FXR targetsMolecular pathways in non-alcoholic fatty liver disease.Plasma bile acids are not associated with energy metabolism in humans.Farnesoid X receptor induces murine scavenger receptor Class B type I via intron binding.Synthetic FXR agonist GW4064 prevents diet-induced hepatic steatosis and insulin resistance.The farnesoid X receptor: a novel drug target?The ileal lipid binding protein is required for efficient absorption and transport of bile acids in the distal portion of the murine small intestine.Cholestasis and hypercholesterolemia in SCD1-deficient mice fed a low-fat, high-carbohydrate diet.Deciphering the nuclear bile acid receptor FXR paradigm.Impact of global Fxr deficiency on experimental acute pancreatitis and genetic variation in the FXR locus in human acute pancreatitis.Ezetimibe restores biliary cholesterol excretion in mice expressing Niemann-Pick C1-Like 1 only in liverFXR: the key to benefits in bariatric surgery?Intestinal transport and metabolism of bile acidsCholic acid induces a Cftr dependent biliary secretion and liver growth response in mice.Bile Acids as Hormones: The FXR-FGF15/19 PathwayLoss of FXR protects against diet-induced obesity and accelerates liver carcinogenesis in ob/ob mice.Cyclosporin A induced toxicity in mouse liver slices is only slightly aggravated by Fxr-deficiency and co-occurs with upregulation of pro-inflammatory genes and downregulation of genes involved in mitochondrial functions.Regulation of bile acid homeostasis by the intestinal Diet1-FGF15/19 axis.The enterohepatic nuclear receptors are major regulators of the enterohepatic circulation of bile salts.Hepatic overexpression of Abcb11 in mice promotes the conservation of bile acids within the enterohepatic circulation.Nuclear bile acid receptor FXR as pharmacological target: are we there yet?FXR and PXR: potential therapeutic targets in cholestasis.Endocrine and paracrine role of bile acidsIntestinal bile acid physiology and pathophysiology.Hepatic insulin resistance directly promotes formation of cholesterol gallstones.Sterol regulation of metabolism, homeostasis, and development.
P2860
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P2860
Enterohepatic circulation of bile salts in farnesoid X receptor-deficient mice: efficient intestinal bile salt absorption in the absence of ileal bile acid-binding protein
description
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2003
@ast
im Oktober 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/10/24)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/10/24)
@nl
наукова стаття, опублікована в жовтні 2003
@uk
name
Enterohepatic circulation of b ...... leal bile acid-binding protein
@ast
Enterohepatic circulation of b ...... leal bile acid-binding protein
@en
Enterohepatic circulation of b ...... leal bile acid-binding protein
@nl
type
label
Enterohepatic circulation of b ...... leal bile acid-binding protein
@ast
Enterohepatic circulation of b ...... leal bile acid-binding protein
@en
Enterohepatic circulation of b ...... leal bile acid-binding protein
@nl
prefLabel
Enterohepatic circulation of b ...... leal bile acid-binding protein
@ast
Enterohepatic circulation of b ...... leal bile acid-binding protein
@en
Enterohepatic circulation of b ...... leal bile acid-binding protein
@nl
P2093
P356
P1476
Enterohepatic circulation of b ...... leal bile acid-binding protein
@en
P2093
Christian V. Hulzebos
Folkert Kuipers
Frans Stellaard
Henk Wolters
Luis B. Agellon
Margrit Schwarz
Rick Havinga
Tineke Kok
P304
41930–41937
P356
10.1074/JBC.M306309200
P407
P577
2003-10-24T00:00:00Z