Hepatic insulin resistance directly promotes formation of cholesterol gallstones. - Wikidata - awgldk - TriplyDB

Hepatic insulin resistance directly promotes formation of cholesterol gallstones.

Hepatic insulin resistance directly promotes formation of cholesterol gallstones.

http://www.wikidata.org/entity/Q37366384

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Epidemiology of gallbladder disease: cholelithiasis and cancer Xylobiose, an Alternative Sweetener, Ameliorates Diabetes-Related Metabolic Changes by Regulating Hepatic Lipogenesis and miR-122a/33a in db/db Mice Determinants for gallstone formation - a new data cohort study and a systematic review with meta-analysis.The association between gallstones and metabolic syndrome in urban Han Chinese: a longitudinal cohort study Elevated Whole-Blood Viscosity is Associated with Gallstones.The number of metabolic abnormalities associated with the risk of gallstones in a non-diabetic population.Early hepatic insulin resistance in mice: a metabolomics analysis.Acceleration of biliary cholesterol secretion restores glycemic control and alleviates hypertriglyceridemia in obese db/db mice.The ABCG5 ABCG8 sterol transporter and phytosterols: implications for cardiometabolic disease Hepatic FoxO1 ablation exacerbates lipid abnormalities during hyperglycemia Plasma metabolomic profile in nonalcoholic fatty liver disease.Androgen receptor roles in insulin resistance and obesity in males: the linkage of androgen-deprivation therapy to metabolic syndrome High incidence of cholesterol gallstone disease in type 1 Gaucher disease: characterizing the biliary phenotype of type 1 Gaucher disease.Gallbladder gallstone disease is associated with newly diagnosed coronary artery atherosclerotic disease: a cross-sectional study.Disruption of the murine protein kinase Cbeta gene promotes gallstone formation and alters biliary lipid and hepatic cholesterol metabolism Hyperhomocysteinemia from trimethylation of hepatic phosphatidylethanolamine during cholesterol cholelithogenesis in inbred mice.Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis.Molecular Mechanisms Underlying the Link between Nuclear Receptor Function and Cholesterol Gallstone Formation.Impaired generation of 12-hydroxylated bile acids links hepatic insulin signaling with dyslipidemia.Hepatic deletion of SIRT1 decreases hepatocyte nuclear factor 1α/farnesoid X receptor signaling and induces formation of cholesterol gallstones in mice.Protein mediators of sterol transport across intestinal brush border membrane.A population-based cohort study of symptomatic gallstone disease in diabetic patients.Delineation of biochemical, molecular, and physiological changes accompanying bile acid pool size restoration in Cyp7a1(-/-) mice fed low levels of cholic acid Gallstone disease is associated with more severe liver damage in patients with non-alcoholic fatty liver disease.GRP78 rescues the ABCG5 ABCG8 sterol transporter in db/db mice Gallstone disease and mortality: a cohort study.The ABCG5 ABCG8 sterol transporter opposes the development of fatty liver disease and loss of glycemic control independently of phytosterol accumulation Diabetes mellitus and the risk of cholangiocarcinoma: an updated meta-analysis.Unsuppressed lipolysis in adipocytes is linked with enhanced gluconeogenesis and altered bile acid physiology in Insr(P1195L/+) mice fed high-fat-diet.Insulin Dissociates the Effects of Liver X Receptor on Lipogenesis, Endoplasmic Reticulum Stress, and Inflammation.Re-adopting classical nuclear receptors by cholesterol metabolites.Diabetes and risk of cancer.Risk Factors for Gallstone Formation in Resected Gastric Cancer Patients Carbohydrate intake as a risk factor for biliary sludge and stones during pregnancy.Prevention of gallbladder hypomotility via FATP2 inhibition protects from lithogenic diet-induced cholelithiasis NSBP-1 mediates the effects of cholesterol on insulin/IGF-1 signaling in Caenorhabditis elegans.Osteopontin Deficiency Alters Biliary Homeostasis and Protects against Gallstone Formation Increased susceptibility to diet-induced gallstones in liver fatty acid binding protein knockout mice.Hepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6 Emerging new paradigms for ABCG transporters.

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Hepatic insulin resistance directly promotes formation of cholesterol gallstones.

http://www.wikidata.org/entity/Q37366384

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 29 June 2008

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Hepatic insulin resistance directly promotes formation of cholesterol gallstones.

@en

Hepatic insulin resistance directly promotes formation of cholesterol gallstones.

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type

label

Hepatic insulin resistance directly promotes formation of cholesterol gallstones.

@en

Hepatic insulin resistance directly promotes formation of cholesterol gallstones.

@nl

prefLabel

Hepatic insulin resistance directly promotes formation of cholesterol gallstones.

@en

Hepatic insulin resistance directly promotes formation of cholesterol gallstones.

@nl

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Nature Medicine

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Hepatic insulin resistance directly promotes formation of cholesterol gallstones.

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Bian B Yu

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Enxuan Jing

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Joel T Haas

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Martin C Carey

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Olivier Bezy

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Sudha B Biddinger

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Terry G Unterman

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Wenwei Zhang

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P2860

ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion

Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report

Comparative genome analysis of potential regulatory elements in the ABCG5-ABCG8 gene cluster

Expression of ABCG5 and ABCG8 is required for regulation of biliary cholesterol secretion

Enterohepatic circulation of bile salts in farnesoid X receptor-deficient mice: efficient intestinal bile salt absorption in the absence of ileal bile acid-binding protein

Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion.

Effects of obesity and caloric intake on biliary lipid metabolism in man.

The effects of chenodiol on biliary lipids and their association with gallstone dissolution in the National Cooperative Gallstone Study (NCGS).

Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis

New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c.

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778-782

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10.1038/NM1785

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5267353

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18587407

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