Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus
about
Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected]Abnormal conduction and morphology in the atrioventricular node of mice with atrioventricular canal targeted deletion of Alk3/Bmpr1a receptorGene regulatory networks in cardiac conduction system developmentThe cardiac conduction systemTumor-Derived Factors and Reduced p53 Promote Endothelial Cell Centrosome Over-DuplicationLethal arrhythmias in Tbx3-deficient mice reveal extreme dosage sensitivity of cardiac conduction system function and homeostasisOverexpression of bone morphogenetic protein 10 in myocardium disrupts cardiac postnatal hypertrophic growthLigand-specific function of transforming growth factor beta in epithelial-mesenchymal transition in heart developmentNotch signaling regulates murine atrioventricular conduction and the formation of accessory pathways.BMP4 is required in the anterior heart field and its derivatives for endocardial cushion remodeling, outflow tract septation, and semilunar valve developmentOutflow tract cushions perform a critical valve-like function in the early embryonic heart requiring BMPRIA-mediated signaling in cardiac neural crestDefective Tbx2-dependent patterning of the atrioventricular canal myocardium causes accessory pathway formation in miceVessel wall BAMBI contributes to hemostasis and thrombus stability.Development of electrocardiogram intervals during growth of FVB/N neonate mice.Bmp2 and Bmp4 genetically interact to support multiple aspects of mouse development including functional heart development.Genetic interaction between Bmp2 and Bmp4 reveals shared functions during multiple aspects of mouse organogenesis.Cell autonomous requirement of endocardial Smad4 during atrioventricular cushion development in mouse embryosBone Morphogenetic Protein (BMP) signaling in development and human diseasesAlk3 mediated Bmp signaling controls the contribution of epicardially derived cells to the tissues of the atrioventricular junctionMyoR modulates cardiac conduction by repressing Gata4.A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway.Genetic Variants in Isolated Ebstein Anomaly Implicated in Myocardial Development Pathways.Myocardial Mycn is essential for mouse ventricular wall morphogenesis.Periostin regulates atrioventricular valve maturation.Recruitment of new cells into the postnatal heart: potential modification of phenotype by periostin.BMP-2 induces cell migration and periostin expression during atrioventricular valvulogenesis.Functional BMP receptor in endocardial cells is required in atrioventricular cushion mesenchymal cell formation in chickSmooth muscle protein 22alpha-mediated patchy deletion of Bmpr1a impairs cardiac contractility but protects against pulmonary vascular remodeling.20p12.3 microdeletion predisposes to Wolff-Parkinson-White syndrome with variable neurocognitive deficits.Periostin as a heterofunctional regulator of cardiac development and diseaseCx30.2 enhancer analysis identifies Gata4 as a novel regulator of atrioventricular delay.Histology atlas of the developing mouse heart with emphasis on E11.5 to E18.5.Pax8 plays a pivotal role in regulation of cardiomyocyte growth and senescence.Expression and deposition of fibrous extracellular matrix proteins in cardiac valves during chick development.Congenital anomalies of the mitral valve.Origin and development of the atrioventricular myocardial lineage: insight into the development of accessory pathways.Co-ordinating Notch, BMP, and TGF-β signaling during heart valve development.Complex Ebstein's malformation: defining preoperative cardiac anatomy and function.Cardiac outflow tract anomalies.Misinterpretation of the mouse ECG: 'musing the waves of Mus musculus'.
P2860
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P2860
Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus
description
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im August 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/08/05)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/08/05)
@nl
наукова стаття, опублікована в серпні 2005
@uk
مقالة علمية (نشرت في 5-8-2005)
@ar
name
Alk3/Bmpr1a receptor is requir ...... to valves and annulus fibrosus
@ast
Alk3/Bmpr1a receptor is requir ...... to valves and annulus fibrosus
@en
Alk3/Bmpr1a receptor is requir ...... to valves and annulus fibrosus
@nl
type
label
Alk3/Bmpr1a receptor is requir ...... to valves and annulus fibrosus
@ast
Alk3/Bmpr1a receptor is requir ...... to valves and annulus fibrosus
@en
Alk3/Bmpr1a receptor is requir ...... to valves and annulus fibrosus
@nl
prefLabel
Alk3/Bmpr1a receptor is requir ...... to valves and annulus fibrosus
@ast
Alk3/Bmpr1a receptor is requir ...... to valves and annulus fibrosus
@en
Alk3/Bmpr1a receptor is requir ...... to valves and annulus fibrosus
@nl
P2093
P2860
P3181
P1433
P1476
Alk3/Bmpr1a receptor is requir ...... to valves and annulus fibrosus
@en
P2093
Christophe Depre
Chull Hong
Dina Myers
Glenn I. Fishman
Gregory E. Morley
John B. E. Burch
Kendra M. Vance
Lorin Emile
P2860
P304
P3181
P356
10.1161/01.RES.0000177862.85474.63
P577
2005-08-05T00:00:00Z