A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection
about
The guanine cap of human guanylate-binding protein 1 is responsible for dimerization and self-activation of GTP hydrolysisAutophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulationGBP5 promotes NLRP3 inflammasome assembly and immunity in mammalsAutophagy protects against active tuberculosis by suppressing bacterial burden and inflammationImmune response and immunopathology during toxoplasmosisMechanisms of Memory T Cell Activation and Effective ImmunityThe cytoskeleton in cell-autonomous immunity: structural determinants of host defenceCellular and Molecular Connections between Autophagy and InflammationDifferential effects of type I and II interferons on myeloid cells and resistance to intracellular bacterial infectionsUse and abuse of dendritic cells by Toxoplasma gondiiCellular self-defense: how cell-autonomous immunity protects against pathogensThe alternative translational profile that underlies the immune-evasive state of persistence in Chlamydiaceae exploits differential tryptophan contents of the protein repertoireStriking the Right Balance Determines TB or Not TBIFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic AcidTranscriptomic Analysis of Persistent Infection with Foot-and-Mouth Disease Virus in Cattle Suggests Impairment of Apoptosis and Cell-Mediated Immunity in the NasopharynxInflammatory stimuli reprogram macrophage phagocytosis to macropinocytosis for the rapid elimination of pathogensThe polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18Pathophysiological role of guanylate-binding proteins in gastrointestinal diseasesBacterial recognition pathways that lead to inflammasome activationEvolution of Cell-Autonomous Effector Mechanisms in Macrophages versus Non-Immune CellsInterferon-induced guanylate-binding proteins in inflammasome activation and host defenseGenomic structural variations for cardiovascular and metabolic comorbidityCell death of gamma interferon-stimulated human fibroblasts upon Toxoplasma gondii infection induces early parasite egress and limits parasite replicationThe bacterial pathogen Listeria monocytogenes and the interferon family: type I, type II and type III interferonsPathways of antigen processing.Getting "Inside" Type I IFNs: Type I IFNs in Intracellular Bacterial InfectionsDown regulation of macrophage IFNGR1 exacerbates systemic L. monocytogenes infectionMemory-T-cell-derived interferon-γ instructs potent innate cell activation for protective immunity.The parasitophorous vacuole membrane of Toxoplasma gondii is targeted for disruption by ubiquitin-like conjugation systems of autophagy.Modulation of innate immunity by Toxoplasma gondii virulence effectors.Interferon-inducible effector mechanisms in cell-autonomous immunity.The Toxoplasma pseudokinase ROP5 is an allosteric inhibitor of the immunity-related GTPases.Cell-autonomous effector mechanisms against mycobacterium tuberculosis.Latent tuberculosis infection: myths, models, and molecular mechanismsCaspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.Nonstructural protein 1 of influenza A virus interacts with human guanylate-binding protein 1 to antagonize antiviral activityGuanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii.IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteinsThe Sculpting of the Mycobacterium tuberculosis Genome by Host Cell-Derived PressuresCytosolic phospholipase A(2)α and eicosanoids regulate expression of genes in macrophages involved in host defense and inflammation.
P2860
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P2860
A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection
description
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 2011
@ast
im Mai 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/05/06)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/05/06)
@nl
наукова стаття, опублікована в травні 2011
@uk
name
A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection
@ast
A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection
@en
A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection
@nl
type
label
A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection
@ast
A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection
@en
A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection
@nl
prefLabel
A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection
@ast
A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection
@en
A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection
@nl
P2093
P2860
P3181
P356
P1433
P1476
A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection
@en
P2093
Bae-Hoon Kim
John D. MacMicking
Pradeep Kumar
Rituparna Das
Sangeeta Tiwari
P2860
P304
P3181
P356
10.1126/SCIENCE.1201711
P407
P577
2011-05-06T00:00:00Z