Act1, a negative regulator in CD40- and BAFF-mediated B cell survival
about
Exploring BAFF: its expression, receptors and contribution to the immunopathogenesis of Sjögren's syndromeRoles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functionsNon-Canonical NF-κB Signaling Initiated by BAFF Influences B Cell Biology at Multiple JuncturesDoes antigen masking by ubiquitin chains protect from the development of autoimmune diseases?Carabin deficiency in B cells increases BCR-TLR9 costimulation-induced autoimmunityTh 17 cells interplay with Foxp3+ Tregs in regulation of inflammation and autoimmunity.Act1 mediates IL-17-induced EAE pathogenesis selectively in NG2+ glial cellsThe differential regulation of human ACT1 isoforms by Hsp90 in IL-17 signalingB cell signature during inactive systemic lupus is heterogeneous: toward a biological dissection of lupus.An essential role of interleukin-17 receptor signaling in the development of autoimmune glomerulonephritisA protein secreted by the respiratory pathogen Chlamydia pneumoniae impairs IL-17 signalling via interaction with human Act1A custom 148 gene-based resequencing chip and the SNP explorer software: new tools to study antibody deficiency.The adaptor protein CIKS/ACT1 is necessary for collagen-induced arthritis, and it contributes to the production of collagen-specific antibodyA BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling.The critical role of epithelial-derived Act1 in IL-17- and IL-25-mediated pulmonary inflammation.Ubiquitin makes its mark on immune regulation.Differential TRAF3 utilization by a variant human CD40 receptor with enhanced signalingAstrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitisGenome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2Differential expression of the adaptor protein HSH2 controls the quantitative and qualitative nature of the humoral response.Systematic dissection of coding exons at single nucleotide resolution supports an additional role in cell-specific transcriptional regulation.Deficiency of Act1, a critical modulator of B cell function, leads to development of Sjögren's syndrome.The adaptor molecule Act1 regulates BAFF responsiveness and self-reactive B cell selection during transitional B cell maturationLKB1 inhibition of NF-κB in B cells prevents T follicular helper cell differentiation and germinal center formation.Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability.Epithelial cell-specific Act1 adaptor mediates interleukin-25-dependent helminth expulsion through expansion of Lin(-)c-Kit(+) innate cell population.A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4-ERK5 axis.IL-17-induced Act1-mediated signaling is critical for cuprizone-induced demyelinationMultiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival.BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway.A unique B2 B cell subset in the intestine.Animal models in autoimmune diseases: lessons learned from mouse models for Sjögren's syndrome.Lack of T cells in Act1-deficient mice results in elevated IgM-specific autoantibodies but reduced lupus-like disease.Structure-function relationships in the IL-17 receptor: implications for signal transduction and therapyThe adaptor protein CIKS/Act1 is essential for IL-25-mediated allergic airway inflammationThe BLyS family: toward a molecular understanding of B cell homeostasis.An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis.Chronic mucocutaneous candidiasis disease associated with inborn errors of IL-17 immunity.IL-17 signaling in host defense and inflammatory diseases.Use of forward genetics to discover novel regulators of NF-kappaB.
P2860
Q26770648-DD889263-2FE1-4568-94FF-947100F194D4Q26853280-8EFD89CD-FD57-471F-88BD-BACD9E325F4CQ27024640-AD685371-0113-4D47-BBEE-CE04B5C4EDCCQ28387136-DA903B6E-6EA9-46E2-AA70-73C804156638Q28594927-BAA0CD14-3D22-4397-963F-B0395FA1561CQ33894387-E17BCD6C-A859-4A53-8873-3B631C23F45AQ33930062-4DA7CE8A-9E56-432D-8F98-E97002D0CAB7Q33992530-B303E6EA-A5CC-4978-92A4-35727B3247ECQ34009020-AB74F6BA-DB42-44E9-A396-E5A788319442Q34066698-42219E8D-B533-48D4-AA9B-3F93D951176CQ34082096-9DD27AF6-61AF-42B6-BBC6-B31F97DBC0D1Q34155993-278CA2A9-132F-48E5-B552-E3BD6BB889DCQ34267915-089177E1-1927-45F7-A17D-603A0001585EQ34340672-DBA49137-C8F1-48AD-A97C-8441ACE864E7Q34462791-46208331-3147-4717-BD5F-3B23D64977F7Q34539820-DF594163-FC4D-409A-819B-A09C0FFDFD37Q34580224-E7FD2A2E-87DF-407C-A892-468C0BB452ABQ34777465-2F5FB49F-5742-4B79-856B-B26103677FB4Q35105452-E53C8B2C-A60B-48E5-9D16-DE9CF398BF2BQ35228256-9FE47433-294E-4553-8B35-9A3407FFBDF1Q35360972-CFF7270C-1785-454B-B411-A7B2B2817ECAQ35576410-C1341A98-9737-460C-871B-FF5BF8A5D6EDQ35576420-26861074-EBE2-4E11-B25B-C15AE27E31F8Q35743804-624C127F-8269-4CBC-9ED6-277E887F1B2BQ35797634-84F7F049-FF42-4784-875D-F2B59CD69C43Q36038191-04DCA256-CA6B-419F-A181-488AD99D1175Q36080701-90FCDAA0-A72F-4F47-BA5D-E1BDDFB32241Q36142154-C0EA3288-F691-4C4C-AB32-67E808D3165EQ36384731-0922D9D3-1949-466B-8508-66A5272D0B6CQ36403102-249BF13E-50F2-46AB-8140-EB49FD55DAC5Q36699766-6285F28E-E6CC-486C-910D-6255DB482A35Q37016308-8188D94E-698B-4045-AA6E-3AE127B5F90CQ37017346-368CD0A3-1C62-4954-8A7A-ABC97A930731Q37051768-B85E1A47-2168-4A66-B583-6C70F61A3AE1Q37070709-2DF7B248-FB7E-4B20-9FA6-BA2DBB43321FQ37335169-3520BCFB-AC8D-45ED-88AA-E031346EE5E3Q37416405-EDB1D884-B5A8-47F0-8523-E22291BBFFC0Q37538514-C7D7CB58-A1F0-483B-AB12-B3312D3F1B10Q37728649-05C2ADB7-DC7C-4B0C-A336-360941D5A05AQ37762070-2619C939-B5DB-4C06-B629-CF19AC549E10
P2860
Act1, a negative regulator in CD40- and BAFF-mediated B cell survival
description
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Oktober 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/10/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/10/01)
@nl
наукова стаття, опублікована в жовтні 2004
@uk
مقالة علمية (نشرت في أكتوبر 2004)
@ar
name
Act1, a negative regulator in CD40- and BAFF-mediated B cell survival
@ast
Act1, a negative regulator in CD40- and BAFF-mediated B cell survival
@en
Act1, a negative regulator in CD40- and BAFF-mediated B cell survival
@nl
type
label
Act1, a negative regulator in CD40- and BAFF-mediated B cell survival
@ast
Act1, a negative regulator in CD40- and BAFF-mediated B cell survival
@en
Act1, a negative regulator in CD40- and BAFF-mediated B cell survival
@nl
prefLabel
Act1, a negative regulator in CD40- and BAFF-mediated B cell survival
@ast
Act1, a negative regulator in CD40- and BAFF-mediated B cell survival
@en
Act1, a negative regulator in CD40- and BAFF-mediated B cell survival
@nl
P2093
P921
P1433
P1476
Act1, a negative regulator in CD40- and BAFF-mediated B cell survival
@en
P2093
Brian L. Kotzin
Carl F. Ware
E. Charles Snow
Jinzhong Qin
Martin Scott
Mayumi Naramura
Robert C. Rickert
Robert L. Fairchild
Sidne A. Omori
P304
P356
10.1016/J.IMMUNI.2004.09.001
P407
P577
2004-10-01T00:00:00Z