Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2 - Wikidata - awgldk - TriplyDB

Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

http://www.wikidata.org/entity/Q35105452

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Genetics of psoriasis and pharmacogenetics of biological drugs The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings Confirmation of TNIP1 and IL23A as susceptibility loci for psoriatic arthritis The roles and functional mechanisms of interleukin-17 family cytokines in mucosal immunity Identifying a novel locus for psoriatic arthritis From genetics of inflammatory bowel disease towards mechanistic insights IL-17 family: cytokines, receptors and signaling Effect of IL-17 receptor A blockade with brodalumab in inflammatory diseases Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci Genome-wide meta-analysis of psoriatic arthritis identifies susceptibility locus at REL Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis.Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis.Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.Graphical algorithm for integration of genetic and biological data: proof of principle using psoriasis as a model An in-depth characterization of the major psoriasis susceptibility locus identifies candidate susceptibility alleles within an HLA-C enhancer element.Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants.A genetic risk score combining ten psoriasis risk loci improves disease prediction.The differential regulation of human ACT1 isoforms by Hsp90 in IL-17 signaling Fine mapping major histocompatibility complex associations in psoriasis and its clinical subtypes IL-17 drives psoriatic inflammation via distinct, target cell-specific mechanisms.Association analysis identifies ZNF750 regulatory variants in psoriasis.Performance of genotype imputations using data from the 1000 Genomes Project.Immunochip identifies novel, and replicates known, genetic risk loci for rheumatoid arthritis in black South Africans DNA methylation and gene expression changes in monozygotic twins discordant for psoriasis: identification of epigenetically dysregulated genes Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis.Genotype imputation for African Americans using data from HapMap phase II versus 1000 genomes projects.Gene expression in skin and lymphoblastoid cells: Refined statistical method reveals extensive overlap in cis-eQTL signals Which Psoriasis Patients Develop Psoriatic Arthritis?Comprehensive exploration of the effects of miRNA SNPs on monocyte gene expression Psoriasis in skin of color: epidemiology, genetics, clinical presentation, and treatment nuances.PSORS2 is due to mutations in CARD14.Genetic Epidemiology of Psoriasis Functional analysis of the RNF114 psoriasis susceptibility gene implicates innate immune responses to double-stranded RNA in disease pathogenesis.Allele-specific network reveals combinatorial interaction that transcends small effects in psoriasis GWAS.The Th17 axis in psoriatic disease: pathogenetic and therapeutic implications.Systematic dissection of coding exons at single nucleotide resolution supports an additional role in cell-specific transcriptional regulation.Psoriasis and cardiometabolic traits: modest association but distinct genetic architectures.The c-Rel Transcription Factor in Development and Disease.

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P2860

Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

http://www.wikidata.org/entity/Q35105452

description

2010 nî lūn-bûn

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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

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Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

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Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

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type

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Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

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Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

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Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

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Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

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Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

@en

Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

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Nature Genetics

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Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

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Andre Franke

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Bernadette Eberlein

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Claudia Reinhard

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David Ellinghaus

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Dieter Kabelitz

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Gabriele Mayr

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Hélène Fournier

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James T Elder

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Johann Gudjonsson

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John J Voorhees

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P2860

A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci

Distinct molecular mechanism for initiating TRAF6 signalling

dbSNP: the NCBI database of genetic variation

A second generation human haplotype map of over 3.1 million SNPs

Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways

PLINK: a tool set for whole-genome association and population-based linkage analyses

A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

Activation of NF-kappaB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-kappaB-inducing kinase. Identification of a novel TRAF6 interaction motif

Act1, a negative regulator in CD40- and BAFF-mediated B cell survival

Genotype imputation

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991-995

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10.1038/NG.689

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P433

11

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42

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Heinz Erich Wichmann

Gonçalo Abecasis

Christian Gieger

Dafna D. Gladman

Sylviane Lambert

Stephan Weidinger

P577

2010-10-17T00:00:00Z

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47450461

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20953188

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genome-wide association study

susceptibility locus

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3136364

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