A unique and specific interaction between alphaT-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs
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A new perspective on intercalated disc organization: implications for heart diseaseMutations in the area composita protein αT-catenin are associated with arrhythmogenic right ventricular cardiomyopathyXin proteins and intercalated disc maturation, signaling and diseasesN-cadherin/catenin complex as a master regulator of intercalated disc functionPlakophilins: multifunctional scaffolds for adhesion and signalingLoss of cadherin-binding proteins β-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesisPlakophilin 2 couples actomyosin remodeling to desmosomal plaque assembly via RhoA.A novel kind of tumor type-characteristic junction: plakophilin-2 as a major protein of adherens junctions in cardiac myxomataThe cardiac protein αT-catenin contributes to chemical-induced asthmaNew functions for alpha-catenins in health and disease: from cancer to heart regenerationMyozap, a novel intercalated disc protein, activates serum response factor-dependent signaling and is required to maintain cardiac function in vivoPlakophilin 3 mediates Rap1-dependent desmosome assembly and adherens junction maturation.A CTNNA3 compound heterozygous deletion implicates a role for αT-catenin in susceptibility to autism spectrum disorderThe evolutionary history of the catenin gene family during metazoan evolution.Desmosomal molecules in and out of adhering junctions: normal and diseased States of epidermal, cardiac and mesenchymally derived cells.The biology of the desmosome-like junction a versatile anchoring junction and signal transducer in the seminiferous epithelium.Protein LUMA is a cytoplasmic plaque constituent of various epithelial adherens junctions and composite junctions of myocardial intercalated disks: a unifying finding for cell biology and cardiology.Anchoring junctions as drug targets: role in contraceptive development.Alpha-catenins control cardiomyocyte proliferation by regulating Yap activity.Abnormal connexin43 in arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 mutations.Loss of αT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemiaAnalysis of a Jup hypomorphic allele reveals a critical threshold for postnatal viability.N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility.Plakophilin-2 loss promotes TGF-β1/p38 MAPK-dependent fibrotic gene expression in cardiomyocytes.Beyond β-catenin: prospects for a larger catenin network in the nucleusTransmembrane protein PERP is a component of tessellate junctions and of other junctional and non-junctional plasma membrane regions in diverse epithelial and epithelium-derived cells.αT-Catenin Is a Constitutive Actin-binding α-Catenin That Directly Couples the Cadherin·Catenin Complex to Actin FilamentsDiscovering the molecular components of intercellular junctions--a historical view.The junctions that don't fit the scheme: special symmetrical cell-cell junctions of their own kind.Alpha T-catenin (CTNNA3): a gene in the hand is worth two in the nest.Desmosomes in the heart: a review of clinical and mechanistic analyses.Alterations in cell adhesion proteins and cardiomyopathy.Arrhythmogenic cardiomyopathy: a disease of intercalated discs.Cardiomyocytes of the Heart and Pulmonary Veins: Novel Contributors to Asthma?Intermediate Filaments and the Plasma Membrane.Plakophilin-2: a cell-cell adhesion plaque molecule of selective and fundamental importance in cardiac functions and tumor cell growthUnmasking the molecular link between arrhythmogenic cardiomyopathy and Brugada syndrome.Gene Mutations Resulting in the Development of ARVC/D Could Affect Cells of the Cardiac Conduction System.Intercalated disc in failing hearts from patients with dilated cardiomyopathy: Its role in the depressed left ventricular function.Releasing YAP from an α-catenin trap increases cardiomyocyte proliferation.
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P2860
A unique and specific interaction between alphaT-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs
description
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im Juni 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/06/15)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/06/15)
@nl
наукова стаття, опублікована в червні 2007
@uk
مقالة علمية (نشرت في 15-6-2007)
@ar
name
A unique and specific interact ...... of cardiac intercalated discs
@ast
A unique and specific interact ...... of cardiac intercalated discs
@en
A unique and specific interact ...... of cardiac intercalated discs
@nl
type
label
A unique and specific interact ...... of cardiac intercalated discs
@ast
A unique and specific interact ...... of cardiac intercalated discs
@en
A unique and specific interact ...... of cardiac intercalated discs
@nl
prefLabel
A unique and specific interact ...... of cardiac intercalated discs
@ast
A unique and specific interact ...... of cardiac intercalated discs
@en
A unique and specific interact ...... of cardiac intercalated discs
@nl
P2093
P921
P3181
P356
P1476
A unique and specific interact ...... of cardiac intercalated discs
@en
P2093
Barbara Janssens
Filip Braet
Frans van Roy
Jolanda van Hengel
Riet De Rycke
Stefan Bonné
Steven Goossens
P304
P3181
P356
10.1242/JCS.004713
P407
P577
2007-06-15T00:00:00Z