Loss of αT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia
about
Mutations in the area composita protein αT-catenin are associated with arrhythmogenic right ventricular cardiomyopathyOrigin and loss of nested LRRTM/α-catenin genes during vertebrate evolutionN-cadherin/catenin complex as a master regulator of intercalated disc functionHeterogeneity of ATP-sensitive K+ channels in cardiac myocytes: enrichment at the intercalated diskThe cardiomyocyte protein αT-catenin contributes to asthma through regulating pulmonary vein inflammationThe cardiac protein αT-catenin contributes to chemical-induced asthmaNew functions for alpha-catenins in health and disease: from cancer to heart regenerationTRPV2 is critical for the maintenance of cardiac structure and function in mice.A CTNNA3 compound heterozygous deletion implicates a role for αT-catenin in susceptibility to autism spectrum disorderCardiomyocyte growth and sarcomerogenesis at the intercalated disc.Cdon deficiency causes cardiac remodeling through hyperactivation of WNT/β-catenin signalingAlpha-catenins control cardiomyocyte proliferation by regulating Yap activity.Super-resolution imaging reveals that loss of the C-terminus of connexin43 limits microtubule plus-end capture and NaV1.5 localization at the intercalated disc.Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice.Development of a Targeted Multi-Disorder High-Throughput Sequencing Assay for the Effective Identification of Disease-Causing Variants.Myocyte-fibroblast communication in cardiac fibrosis and arrhythmias: Mechanisms and model systems.Deletion of the last five C-terminal amino acid residues of connexin43 leads to lethal ventricular arrhythmias in mice without affecting coupling via gap junction channels.Transmembrane protein PERP is a component of tessellate junctions and of other junctional and non-junctional plasma membrane regions in diverse epithelial and epithelium-derived cells.Regulation of cardiovascular connexins by mechanical forces and junctions.αT-catenin in restricted brain cell types and its potential connection to autism.αT-Catenin Is a Constitutive Actin-binding α-Catenin That Directly Couples the Cadherin·Catenin Complex to Actin FilamentsArrhythmogenic cardiomyopathy and Brugada syndrome: diseases of the connexome.Desmosomes in the heart: a review of clinical and mechanistic analyses.Myozap Deficiency Promotes Adverse Cardiac Remodeling via Differential Regulation of Mitogen-activated Protein Kinase/Serum-response Factor and β-Catenin/GSK-3β Protein Signaling.Cardiomyocytes of the Heart and Pulmonary Veins: Novel Contributors to Asthma?Overview of the Muscle Cytoskeleton.Unmasking the molecular link between arrhythmogenic cardiomyopathy and Brugada syndrome.Intercalated disc in failing hearts from patients with dilated cardiomyopathy: Its role in the depressed left ventricular function.Long-term miR-669a therapy alleviates chronic dilated cardiomyopathy in dystrophic mice.Releasing YAP from an α-catenin trap increases cardiomyocyte proliferation.Cell-cell adhesion genes CTNNA2 and CTNNA3 are tumour suppressors frequently mutated in laryngeal carcinomas.A 10q21.3q22.2 microdeletion identified in a patient with severe developmental delay and multiple congenital anomalies including congenital heart defects.
P2860
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P2860
Loss of αT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
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2012年论文
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name
Loss of αT-catenin alters the ...... thmia following acute ischemia
@ast
Loss of αT-catenin alters the ...... thmia following acute ischemia
@en
type
label
Loss of αT-catenin alters the ...... thmia following acute ischemia
@ast
Loss of αT-catenin alters the ...... thmia following acute ischemia
@en
prefLabel
Loss of αT-catenin alters the ...... thmia following acute ischemia
@ast
Loss of αT-catenin alters the ...... thmia following acute ischemia
@en
P2093
P2860
P356
P1476
Loss of αT-catenin alters the ...... thmia following acute ischemia
@en
P2093
Frans van Roy
Glenn L Radice
Jolanda van Hengel
Koen Tyberghein
Riet De Rycke
Steven Goossens
Xiying Shang
P2860
P304
P356
10.1242/JCS.098640
P407
P50
P577
2012-02-01T00:00:00Z