Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice
about
Disruption of TTDA results in complete nucleotide excision repair deficiency and embryonic lethalityRestoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiationCockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylaseIncreased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome miceOxidative stress, bone marrow failure, and genome instability in hematopoietic stem cellsDNA repair in human pluripotent stem cells is distinct from that in non-pluripotent human cellsCell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiencyCockayne syndrome B protein stimulates apurinic endonuclease 1 activity and protects against agents that introduce base excision repair intermediatesDifferent effects of CSA and CSB deficiency on sensitivity to oxidative DNA damageRetinal degeneration and ionizing radiation hypersensitivity in a mouse model for Cockayne syndromeThe ERCC6 gene and age-related macular degenerationImpaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome.Porphyrin homeostasis maintained by ABCG2 regulates self-renewal of embryonic stem cellsAn Xpb mouse model for combined xeroderma pigmentosum and cockayne syndrome reveals progeroid features upon further attenuation of DNA repair.Nuclear accumulation and activation of p53 in embryonic stem cells after DNA damage.A genomewide study identifies the Wnt signaling pathway as a major target of p53 in murine embryonic stem cells.Newly identified CHO ERCC3/XPB mutations and phenotype characterization.Cockayne syndrome group B cellular and biochemical functions.The role of XPC: implications in cancer and oxidative DNA damageAge-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathologyDNA repair deficiency in neurodegeneration.Mitochondrial reactive oxygen species are scavenged by Cockayne syndrome B protein in human fibroblasts without nuclear DNA damageUse of the comet-FISH assay to compare DNA damage and repair in p53 and hTERT genes following ionizing radiationOxidative DNA damage and nucleotide excision repair.Preferential repair of oxidized base damage in the transcribed genes of mammalian cellsCockayne syndrome B protects against methamphetamine-enhanced oxidative DNA damage in murine fetal brain and postnatal neurodevelopmental deficitsCockayne syndrome B protein antagonizes OGG1 in modulating CAG repeat length in vivo.Removal of reactive oxygen species-induced 3'-blocked ends by XPF-ERCC1.Xeroderma Pigmentosum Group A Suppresses Mutagenesis Caused by Clustered Oxidative DNA Adducts in the Human GenomeSin3a is essential for the genome integrity and viability of pluripotent cellsPreferential repair of the transcribed DNA strand in plants.The involvement of DNA-damage and -repair defects in neurological dysfunctionA variant of the Cockayne syndrome B gene ERCC6 confers risk of lung cancer.Clinical implications of the basic defects in Cockayne syndrome and xeroderma pigmentosum and the DNA lesions responsible for cancer, neurodegeneration and agingThe role of Cockayne Syndrome group B (CSB) protein in base excision repair and aging.Multiple interaction partners for Cockayne syndrome proteins: implications for genome and transcriptome maintenanceA ubiquitylation site in Cockayne syndrome B required for repair of oxidative DNA damage, but not for transcription-coupled nucleotide excision repairDNA repair in murine embryonic stem cells and differentiated cellsCdk12 is essential for embryonic development and the maintenance of genomic stability.Accumulation of (5'S)-8,5'-cyclo-2'-deoxyadenosine in organs of Cockayne syndrome complementation group B gene knockout mice.
P2860
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P2860
Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice
description
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
scientific journal article
@en
vedecký článok (publikovaný 2003/01/02)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/01/02)
@nl
wissenschaftlicher Artikel
@de
наукова стаття, опублікована в січні 2003
@uk
مقالة علمية (نشرت في 2-1-2003)
@ar
name
Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice
@ast
Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice
@en
Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice
@nl
type
label
Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice
@ast
Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice
@en
Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice
@nl
prefLabel
Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice
@ast
Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice
@en
Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice
@nl
P2093
P3181
P1433
P1476
Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice
@en
P2093
Gerard van den Aardweg
Harm de Waard
Harry van Steeg
Jan H J Hoeijmakers
Jan de Wit
Marcel Vermeij
Theo G M F Gorgels
P3181
P356
10.1016/S1568-7864(02)00188-X
P577
2003-01-01T00:00:00Z