A role for Groucho tetramerization in transcriptional repression
about
Transducin-like enhancer of split proteins, the human homologs of Drosophila groucho, interact with hepatic nuclear factor 3betaA core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafnessPf1, a novel PHD zinc finger protein that links the TLE corepressor to the mSin3A-histone deacetylase complexThe proline-rich homeodomain protein recruits members of the Groucho/Transducin-like enhancer of split protein family to co-repress transcription in hematopoietic cellsGroucho binds two conserved regions of LEF-1 for HDAC-dependent repressionThe PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressorsMolecular functions of the TLE tetramerization domain in Wnt target gene repressionRole for the mortality factors MORF4, MRGX, and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split.Oligomerization of ETO is obligatory for corepressor interactionTranscriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho familyTemporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesisAll Tcf HMG box transcription factors interact with Groucho-related co-repressorsGbx2 and Otx2 interact with the WD40 domain of Groucho/Tle corepressorsRepression by Groucho/TLE/Grg proteins: genomic site recruitment generates compacted chromatin in vitro and impairs activator binding in vivoStructure of the C-terminal domain of Tup1, a corepressor of transcription in yeastA new Groucho TLE4 protein may regulate the repressive activity of Pax5 in human B lymphocytesCell Fate and Differentiation of Bone Marrow Mesenchymal Stem CellsCrystal Structure of the N-terminal Domain of the Yeast General Corepressor Tup1p and Its Functional ImplicationsCloning and characterization of a novel WD-40 repeat protein that dramatically accelerates osteoblastic differentiationrTLE3, a newly identified transducin-like enhancer of split, is induced by depolarization in brainCharacterization of a novel mammalian Groucho isoform and its role in transcriptional regulationA functional interaction between the histone deacetylase Rpd3 and the corepressor groucho in Drosophila developmentThe homeodomain protein NK-3 recruits Groucho and a histone deacetylase complex to repress transcriptionGroucho oligomerization is required for repression in vivoFunctional dissection of the global repressor Tup1 in yeast: dominant role of the C-terminal repression domain.Analysis of the transcription factor WUSCHEL and its functional homologue in Antirrhinum reveals a potential mechanism for their roles in meristem maintenance.Phosphorylation of SU(VAR)3-9 by the chromosomal kinase JIL-1.Groucho-mediated repression may result from a histone deacetylase-dependent increase in nucleosome density.Differential modulation of TCF/LEF-1 activity by the soluble LRP6-ICD.Transcriptional autoregulation and inhibition of mRNA translation of amino acid regulator gene cpcA of filamentous fungus Aspergillus nidulansThe corepressor Tle4 is a novel regulator of murine hematopoiesis and bone development.The unconserved groucho central region is essential for viability and modulates target gene specificity.AES/GRG5: more than just a dominant-negative TLE/GRG family memberRole for Hes1-induced phosphorylation in Groucho-mediated transcriptional repression.The Dorsal Rel homology domain plays an active role in transcriptional regulationRegulation of SMRT corepressor dimerization and composition by MAP kinase phosphorylation.GRG5/AES interacts with T-cell factor 4 (TCF4) and downregulates Wnt signaling in human cells and zebrafish embryos.Keeping a good pathway down: transcriptional repression of Notch pathway target genes by CSL proteinsThe Groucho co-repressor is primarily recruited to local target sites in active chromatin to attenuate transcriptionAn ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP.
P2860
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P2860
A role for Groucho tetramerization in transcriptional repression
description
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
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im Dezember 1998 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 1998/12/01)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/12/01)
@nl
наукова стаття, опублікована в грудні 1998
@uk
مقالة علمية (نشرت في ديسمبر 1998)
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name
A role for Groucho tetramerization in transcriptional repression
@ast
A role for Groucho tetramerization in transcriptional repression
@en
A role for Groucho tetramerization in transcriptional repression
@nl
type
label
A role for Groucho tetramerization in transcriptional repression
@ast
A role for Groucho tetramerization in transcriptional repression
@en
A role for Groucho tetramerization in transcriptional repression
@nl
prefLabel
A role for Groucho tetramerization in transcriptional repression
@ast
A role for Groucho tetramerization in transcriptional repression
@en
A role for Groucho tetramerization in transcriptional repression
@nl
P2093
P2860
P3181
P356
P1476
A role for Groucho tetramerization in transcriptional repression
@en
P2093
A. J. Courey
P. H. Nguyen
P2860
P304
P3181
P356
10.1128/MCB.18.12.7259
P407
P577
1998-12-01T00:00:00Z