Role of disulfide bonds in the structure and activity of human insulin
about
Insulin analog with additional disulfide bond has increased stability and preserved activityClustering of disulfide-rich peptides provides scaffolds for hit discovery by phage display: application to interleukin-23Comprehensive analysis of contributions from protein conformational stability and major histocompatibility complex class II-peptide binding affinity to CD4+ epitope immunogenicity in HIV-1 envelope glycoprotein.Disulfide bridges remain intact while native insulin converts into amyloid fibrilsStructures of Xenopus Embryonic Epidermal Lectin Reveal a Conserved Mechanism of Microbial Glycan Recognition.Proinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes.Additional disulfide bonds in insulin: Prediction, recombinant expression, receptor binding affinity, and stability.Human insulin polymorphism upon ligand binding and pH variation: the case of 4-ethylresorcinol.Disulfide Mispairing During Proinsulin Folding in the Endoplasmic Reticulum.Probing residue-specific interactions in the stabilization of proteins using high-resolution NMR: a study of disulfide bond compensation.On the importance of oxidative folding in the evolution of conotoxins: cysteine codon preservation through gene duplication and adaptation.Reactivity of disulfide bonds is markedly affected by structure and environment: implications for protein modification and stability.Permanent neonatal diabetes in INS(C94Y) transgenic pigs.Production and characterization of neurosecretory protein GM using Escherichia coli and Chinese Hamster Ovary cells.Insulin in motion: The A6-A11 disulfide bond allosterically modulates structural transitions required for insulin activity.Oxidation of cysteine to cystine in ProinsulinProbing the correlation between insulin activity and structural stability through introduction of the rigid A6-A11 bond
P2860
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P2860
Role of disulfide bonds in the structure and activity of human insulin
description
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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artículu científicu espublizáu en 2003
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im Dezember 2003 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2003/12/31)
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vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/12/31)
@nl
наукова стаття, опублікована в грудні 2003
@uk
مقالة علمية (نشرت في 31-12-2003)
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name
Role of disulfide bonds in the structure and activity of human insulin
@ast
Role of disulfide bonds in the structure and activity of human insulin
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Role of disulfide bonds in the structure and activity of human insulin
@nl
type
label
Role of disulfide bonds in the structure and activity of human insulin
@ast
Role of disulfide bonds in the structure and activity of human insulin
@en
Role of disulfide bonds in the structure and activity of human insulin
@nl
prefLabel
Role of disulfide bonds in the structure and activity of human insulin
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Role of disulfide bonds in the structure and activity of human insulin
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Role of disulfide bonds in the structure and activity of human insulin
@nl
P2093
P1433
P1476
Role of disulfide bonds in the structure and activity of human insulin
@en
P2093
Hang-Cheol Shin
Ki-Doo Choi
Seung-Gu Chang
Seung-Hwan Jang
P304
P577
2003-12-31T00:00:00Z