Permanent neonatal diabetes in INS(C94Y) transgenic pigs. - Wikidata - awgldk - TriplyDB

Permanent neonatal diabetes in INS(C94Y) transgenic pigs.

Permanent neonatal diabetes in INS(C94Y) transgenic pigs.

http://www.wikidata.org/entity/Q40124315

about

Engineering large animal models of human disease INS-gene mutations: from genetics and beta cell biology to clinical disease Current progress of genetically engineered pig models for biomedical research Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set.Genetically modified pig models for neurodegenerative disorders.Diffuse glomerular nodular lesions in diabetic pigs carrying a dominant-negative mutant hepatocyte nuclear factor 1-alpha, an inheritant diabetic gene in humans.Effects of the glucagon-like peptide-1 receptor agonist liraglutide in juvenile transgenic pigs modeling a pre-diabetic condition Proinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes.Multi‑transgenic minipig models exhibiting potential for hepatic insulin resistance and pancreatic apoptosis Diet before and during Pregnancy and Offspring Health: The Importance of Animal Models and What Can Be Learned from Them.The new pig on the block: modelling cancer in pigs.Genetically engineered pig models for diabetes research.Genetically modified pigs to model human diseases.The Munich MIDY Pig Biobank - A unique resource for studying organ crosstalk in diabetes.Genetically engineered livestock for biomedical models.Genome editing revolutionize the creation of genetically modified pigs for modeling human diseases.Progress in Clinical Encapsulated Islet Xenotransplantation.Direct introduction of gene constructs into the pronucleus-like structure of cloned embryos: a new strategy for the generation of genetically modified pigs.Genetically engineered pigs as models for human disease.Retinopathy with central oedema in an INS C94Y transgenic pig model of long-term diabetes.Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver.Tissue Sampling Guides for Porcine Biomedical Models.

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P2860

Permanent neonatal diabetes in INS(C94Y) transgenic pigs.

http://www.wikidata.org/entity/Q40124315

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

Permanent neonatal diabetes in INS(C94Y) transgenic pigs.

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type

label

Permanent neonatal diabetes in INS(C94Y) transgenic pigs.

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prefLabel

Permanent neonatal diabetes in INS(C94Y) transgenic pigs.

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Permanent neonatal diabetes in INS(C94Y) transgenic pigs

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Andrea Bähr

http://www.w3.org/2001/XMLSchema#string

Andreas Blutke

http://www.w3.org/2001/XMLSchema#string

Annegret Wünsch

http://www.w3.org/2001/XMLSchema#string

Barbara Kessler

http://www.w3.org/2001/XMLSchema#string

Christina Braun-Reichhart

http://www.w3.org/2001/XMLSchema#string

Daniela Emrich

http://www.w3.org/2001/XMLSchema#string

Elisabeth Streckel

http://www.w3.org/2001/XMLSchema#string

Helmut Blum

http://www.w3.org/2001/XMLSchema#string

Hiroshi Nagashima

http://www.w3.org/2001/XMLSchema#string

Mayuko Kurome

http://www.w3.org/2001/XMLSchema#string

P2860

All in the family: aldose reductase and closely related aldo-keto reductases

Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes

Role of disulfide bonds in the structure and activity of human insulin

Misfolded proinsulin affects bystander proinsulin in neonatal diabetes

In vitro processing and secretion of mutant insulin proteins that cause permanent neonatal diabetes.

Transcriptional, post-transcriptional and epigenetic control of porcine oocyte maturation and embryogenesis.

Improvement of islet function in a bioartificial pancreas by enhanced oxygen supply and growth hormone releasing hormone agonist.

Insulin gene mutations as a cause of permanent neonatal diabetes.

Changing metabolic signatures of amino acids and lipids during the prediabetic period in a pig model with impaired incretin function and reduced β-cell mass.

Seven mutations in the human insulin gene linked to permanent neonatal/infancy-onset diabetes mellitus.

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1505-1511

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10.2337/DB12-1065

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5

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62

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23274907

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