Proinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3 - Wikidata - awgldk - TriplyDB

Proinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3

Proinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3

http://www.wikidata.org/entity/Q28609870

about

Differences between the catalytic properties of recombinant human PC2 and endogenous rat PC2 Processing of prothyrotropin-releasing hormone by the family of prohormone convertases Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins Association of the proprotein convertase subtilisin/kexin-type 2 (PCSK2) gene with type 2 diabetes in an African American population.Kinetics of neuroendocrine differentiation in an androgen-dependent human prostate xenograft model The alphaviruses: gene expression, replication, and evolution Neuroendocrine-specific expression of the human prohormone convertase 1 gene. Hormonal regulation of transcription through distinct cAMP response elements Functional consequences of a novel variant of PCSK1 Identification of a small molecule that selectively inhibits mouse PC2 over mouse PC1/3: a computational and experimental study The neuroendocrine polypeptide 7B2 is an endogenous inhibitor of prohormone convertase PC2 Immunocytochemical localization of the prohormone convertases PC1 and PC2 in rat prolactin cells Immunohistochemical evidence for the involvement of protein convertases 5A and 2 in the processing of pro-neurotensin in rat brain Proinsulin processing in the rat insulinoma cell line INS after overexpression of the endoproteases PC2 or PC3 by recombinant adenovirus Characterization of an insulin from the three-toed amphiuma (Amphibia: Urodela) with an N-terminally extended A-chain and high receptor-binding affinity Expression and secretion of human proinsulin-B10 from mouse salivary glands: implications for the treatment of type I diabetes mellitus.Fusagene vectors: a novel strategy for the expression of multiple genes from a single cistron.Proinsulin is refractory to protein fibrillation: topological protection of a precursor protein from cross-beta assembly.Insulin secretion and insulin-producing tumors Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing.Group X secretory phospholipase A2 regulates insulin secretion through a cyclooxygenase-2-dependent mechanism.Purification and characterization of carboxypeptidase D, a novel carboxypeptidase E-like enzyme, from bovine pituitary.Gene therapy for diabetes mellitus in rats by hepatic expression of insulin.Prodynorphin processing by proprotein convertase 2. Cleavage at single basic residues and enhanced processing in the presence of carboxypeptidase activity.Proprotein convertases in amphioxus: predicted structure and expression of proteases SPC2 and SPC3 Global analysis of cellular proteolysis by selective enzymatic labeling of protein N-termini.Modulation of PC1/3 activity by self-interaction and substrate binding.Proinsulin endoproteolysis confers enhanced targeting of processed insulin to the regulated secretory pathway New markers for pancreatic islets and islet cell tumors.A missing PD-L1/PD-1 coinhibition regulates diabetes induction by preproinsulin-specific CD8 T-cells in an epitope-specific manner Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells.Increased secretory demand rather than a defect in the proinsulin conversion mechanism causes hyperproinsulinemia in a glucose-infusion rat model of non-insulin-dependent diabetes mellitus.Inhibition of prohormone convertases PC1/3 and PC2 by 2,5-dideoxystreptamine derivatives.Topographic abnormalities of proinsulin to insulin conversion in functioning human insulinomas. Comparison of immunoelectron microscopic and clinical data.Islet autoantigens: structure, function, localization, and regulation.The cytoplasmic domain mediates localization of furin to the trans-Golgi network en route to the endosomal/lysosomal system.Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2.Tequila Regulates Insulin-Like Signaling and Extends Life Span in Drosophila melanogaster.Processing of a fusion protein by endoprotease in COS-1 cells for secretion of mature peptide by using a chimeric expression vector.An efficient two-step subcellular fractionation method for the enrichment of insulin granules from INS-1 cells.Intracellular misrouting and abnormal secretion of adrenocorticotropin and growth hormone in cpefat mice associated with a carboxypeptidase E mutation.

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Proinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3

http://www.wikidata.org/entity/Q28609870

description

1992 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

1992 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

article publié dans les Procee ...... f the United States of America

@fr

artículu científicu espublizáu en 1992

@ast

im September 1992 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 1992/09/15)

@sk

vědecký článek publikovaný v roce 1992

@cs

wetenschappelijk artikel (gepubliceerd op 1992/09/15)

@nl

наукова стаття, опублікована у вересні 1992

@uk

name

Proinsulin processing by the s ...... onvertases furin, PC2, and PC3

@ast

Proinsulin processing by the s ...... onvertases furin, PC2, and PC3

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Proinsulin processing by the s ...... onvertases furin, PC2, and PC3

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type

label

Proinsulin processing by the s ...... onvertases furin, PC2, and PC3

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Proinsulin processing by the s ...... onvertases furin, PC2, and PC3

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Proinsulin processing by the s ...... onvertases furin, PC2, and PC3

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prefLabel

Proinsulin processing by the s ...... onvertases furin, PC2, and PC3

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Proinsulin processing by the s ...... onvertases furin, PC2, and PC3

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Proinsulin processing by the s ...... onvertases furin, PC2, and PC3

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PNAS.89.18.8822

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Proceedings of the National Academy of Sciences of the United States of America

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Proinsulin processing by the s ...... onvertases furin, PC2, and PC3

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A. G. Montag

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C. Albiges-Rizo

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G. Thomas

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L. A. Phillips

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M. Benig

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R. Carroll

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S. Martin

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S. Ohagi

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S. P. Smeekens

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P2860

Expression of a human proprotein processing enzyme: correct cleavage of the von Willebrand factor precursor at a paired basic amino acid site

Structural and enzymatic characterization of a purified prohormone-processing enzyme: secreted, soluble Kex2 protease

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures

Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo

Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-alpha-factor

cDNA and gene structure for a human subtilisin-like protease with cleavage specificity for paired basic amino acid residues

Yeast KEX2 genes encodes an endopeptidase homologous to subtilisin-like serine proteases

Identification of a second human subtilisin-like protease gene in the fes/fps region of chromosome 15

Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen

Biosynthesis of the prohormone convertase mPC1 in AtT-20 cells.

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18

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