Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells.
about
Unraveling oxyntomodulin, GLP1's enigmatic brotherAction and therapeutic potential of oxyntomodulinSpecificity and kinetic studies on the cleavage of various prohormone mono- and paired-basic residue sites by yeast aspartic protease 3.Neuroendocrine-specific expression of the human prohormone convertase 1 gene. Hormonal regulation of transcription through distinct cAMP response elementsIsosteviol has beneficial effects on palmitate-induced α-cell dysfunction and gene expressionThe proprotein convertase encoded by amontillado (amon) is required in Drosophila corpora cardiaca endocrine cells producing the glucose regulatory hormone AKH.Two dipolar α-helices within hormone-encoding regions of proglucagon are sorting signals to the regulated secretory pathway.Progressive change of intra-islet GLP-1 production during diabetes developmentBiochemical and cell biological properties of the human prohormone convertase 1/3 Ser357Gly mutation: a PC1/3 hypermorph.Cholecystokinin is up-regulated in obese mouse islets and expands beta-cell mass by increasing beta-cell survivalProglucagon-derived peptides: mechanisms of action and therapeutic potential.amontillado, the Drosophila homolog of the prohormone processing protease PC2, is required during embryogenesis and early larval development.Novel insight into glucagon receptor action: lessons from knockout and transgenic mouse models.The role of incretins in glucose homeostasis and diabetes treatment.Hormonal activity of AIMP1/p43 for glucose homeostasisThe sequence flanking the N-terminus of the CLV3 peptide is critical for its cleavage and activity in stem cell regulation in Arabidopsis.Dynamic modulation of prohormone convertase 2 (PC2)-mediated precursor processing by 7B2 protein: preferential effect on glucagon synthesisCharacterization of a novel functional protein in the pancreatic islet: islet homeostasis protein regulation of glucagon synthesis in α cells.Incretin mimetics as emerging treatments for type 2 diabetes.The incretins: a link between nutrients and well-being.Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2.Teduglutide for the treatment of short bowel syndrome.Targeting glucagon receptor signalling in treating metabolic syndrome and renal injury in Type 2 diabetes: theory versus promiseActivation of Transmembrane Bile Acid Receptor TGR5 Modulates Pancreatic Islet α Cells to Promote Glucose Homeostasis.Postabsorptive hyperglucagonemia in patients with type 2 diabetes mellitus analyzed with a novel enzyme-linked immunosorbent assay.Role of furin in granular acidification in the endocrine pancreas: identification of the V-ATPase subunit Ac45 as a candidate substrate.Pax6 regulates the proglucagon processing enzyme PC2 and its chaperone 7B2.Regulation of pancreatic PC1 and PC2 associated with increased glucagon-like peptide 1 in diabetic ratsGlucagon antagonism as a potential therapeutic target in type 2 diabetes.Regulation by glucose of the biosynthesis of PC2, PC3 and proinsulin in (ob/ob) mouse islets of Langerhans.Modified Western blotting for insulin and other diabetes-associated peptide hormones.Intra-islet glucagon-like peptide 1.PCSK1 Variants and Human Obesity.Role of histamine H3 receptor in glucagon-secreting αTC1.6 cellsProhormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor.Altered proglucagon processing in an alpha-cell line derived from prohormone convertase 2 null mouse islets.Interaction of Drosophila melanogaster prohormone convertase 2 and 7B2. Insect cell-specific processing and secretion.PC5-A-mediated processing of pro-neurotensin in early compartments of the regulated secretory pathway of PC5-transfected PC12 cells.Role of the prohormone convertase PC3 in the processing of proglucagon to glucagon-like peptide 1.Regulation of human prohormone convertase 2 promoter activity by the transcription factor EGR-1.
P2860
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P2860
Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells.
description
1994 nî lūn-bûn
@nan
1994 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
name
Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells.
@ast
Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells.
@en
type
label
Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells.
@ast
Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells.
@en
prefLabel
Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells.
@ast
Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells.
@en
P2093
P2860
P356
P1476
Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells.
@en
P2093
D F Steiner
G Westermark
S K Martin
P2860
P304
P356
10.1073/PNAS.91.8.3242
P407
P577
1994-04-01T00:00:00Z