Characterization of bovine endothelial nitric oxide synthase as a homodimer with down-regulated uncoupled NADPH oxidase activity: tetrahydrobiopterin binding kinetics and role of haem in dimerization
about
Human endothelial dihydrofolate reductase low activity limits vascular tetrahydrobiopterin recyclingAllosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistryCommunication between the Zinc and Tetrahydrobiopterin Binding Sites in Nitric Oxide SynthaseNitric oxide synthases: structure, function and inhibitionNitric oxide synthases: regulation and functionContrasting effects of N5-substituted tetrahydrobiopterin derivatives on phenylalanine hydroxylase, dihydropteridine reductase and nitric oxide synthaseRegulation of cellular communication by signaling microdomains in the blood vessel wall.Hypoxia and reoxygenation induce endothelial nitric oxide synthase uncoupling in endothelial cells through tetrahydrobiopterin depletion and S-glutathionylation.Peroxynitrite induces destruction of the tetrahydrobiopterin and heme in endothelial nitric oxide synthase: transition from reversible to irreversible enzyme inhibitionRole of a Conserved Tyrosine Residue in the FMN-Heme Interdomain Electron Transfer in Inducible Nitric Oxide Synthase.Sepiapterin improves angiogenesis of pulmonary artery endothelial cells with in utero pulmonary hypertension by recoupling endothelial nitric oxide synthase.Serine 1179 Phosphorylation of Endothelial Nitric Oxide Synthase Increases Superoxide Generation and Alters Cofactor Regulation.Syringaresinol causes vasorelaxation by elevating nitric oxide production through the phosphorylation and dimerization of endothelial nitric oxide synthase.Myocardial ischemia results in tetrahydrobiopterin (BH4) oxidation with impaired endothelial function ameliorated by BH4.DNA strand breaks induced by nuclear hijacking of neuronal NOS as an anti-cancer effect of 2-methoxyestradiolSelective Irreversible Inhibition of Neuronal and Inducible Nitric-oxide Synthase in the Combined Presence of Hydrogen Sulfide and Nitric Oxide.Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors.Interaction between neuronal nitric-oxide synthase and tetrahydrobiopterin revisited: studies on the nature and mechanism of tight pterin binding.Induction of microRNA-138 by pro-inflammatory cytokines causes endothelial cell dysfunction.Sesamin ameliorates arterial dysfunction in spontaneously hypertensive rats via downregulation of NADPH oxidase subunits and upregulation of eNOS expression.Cell type-specific recycling of tetrahydrobiopterin by dihydrofolate reductase explains differential effects of 7,8-dihydrobiopterin on endothelial nitric oxide synthase uncoupling.Catalytic reduction of a tetrahydrobiopterin radical within nitric-oxide synthase.Combined oral administration of L-arginine and tetrahydrobiopterin in a rat model of pulmonary arterial hypertension.S-glutathionylation reshapes our understanding of endothelial nitric oxide synthase uncoupling and nitric oxide/reactive oxygen species-mediated signalingAllosteric modulation of rat brain nitric oxide synthase by the pterin-site enzyme inhibitor 4-aminotetrahydrobiopterin.Effects of pH on the structure and function of neuronal nitric oxide synthase.Nitric oxide-induced autoinhibition of neuronal nitric oxide synthase in the presence of the autoxidation-resistant pteridine 5-methyltetrahydrobiopterin.The return of the Scarlet Pimpernel: cobalamin in inflammation II - cobalamins can both selectively promote all three nitric oxide synthases (NOS), particularly iNOS and eNOS, and, as needed, selectively inhibit iNOS and nNOS.Tetrahydrobiopterin redox cycling in nitric oxide synthase: evidence supports a through-heme electron delivery.eNOS synthesizes NO
P2860
Q24293579-699A4D79-177E-433F-8A0F-CD29E36FE6DCQ27621434-6DAA8842-B2CC-4F2F-9932-FFE72303DB35Q27683748-EB004204-3E3A-4074-BFCD-86F2A2AD4D20Q28207668-EC8608A5-5632-4E51-8D1C-01A83D679FE7Q28247092-D739E69A-FBD4-4818-A99C-74DD1636BF4BQ28574134-0CBF093C-9CF9-4EB5-BFE3-A78D39E2C7CFQ30406156-66F515C7-D8B7-4ECF-8A57-1E8B9A7CF953Q33739113-CAD900B9-1F49-450B-8F1C-99FBAD3BDDBAQ33775518-0F21BF11-315E-481A-B5FC-ABE8B9F15AA4Q33926497-605F762D-CA36-4985-9BD1-2C885FA144F4Q35217368-A2401487-B269-4DC2-BAF6-A9CE3C76F923Q35839144-DA3F44CE-6804-457D-9C8E-BEA20E813EA7Q35865615-01A78106-5D19-4685-B4D7-63FDA67DE4CCQ36002621-DF43A773-1841-4606-AC02-BE0F4C27CCB2Q36021044-AD98E743-25DF-4F3F-AC95-17B6F57EF7CEQ36139878-48D0A2D5-560C-4BE2-BC9E-70DA04D60E18Q36253833-40F1B59D-27FF-47CA-BB59-C0075A9ACDCEQ37621624-D73CE178-B87B-4B83-B164-6C242D258BA1Q37683440-95E1CBE8-A58C-413A-B48D-23714F76D730Q37728516-E1FD3375-DDCA-4ADC-BD36-39D2B002E17FQ38991320-867C569D-F247-4731-9115-C4D86A45C4A9Q39263279-294774C2-ACC6-4D9A-8440-564B6C95AC91Q42238880-35639293-9E0B-4DD7-8AE2-5DF1ED224B5BQ42718346-425CF3AE-7D52-49B3-8694-D25CB67F150AQ42988594-C13BD5F3-F7CF-412D-848C-F0D04FF35EA8Q42990485-D5E76BCF-3CCC-4F9E-8D9C-95DAD35C8724Q42996395-414E441B-0E0C-4295-B660-7E73AAB47307Q43011251-7EDEFE18-1E55-4EFE-AEAD-2DE1C9352B75Q50002002-DAC83548-ED55-473E-A876-BF3AB7E36B46Q50294435-197BF66F-096E-406D-9593-75392A2FFE7D
P2860
Characterization of bovine endothelial nitric oxide synthase as a homodimer with down-regulated uncoupled NADPH oxidase activity: tetrahydrobiopterin binding kinetics and role of haem in dimerization
description
1997 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1997
@ast
im April 1997 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1997/04/01)
@sk
vědecký článek publikovaný v roce 1997
@cs
wetenschappelijk artikel (gepubliceerd op 1997/04/01)
@nl
наукова стаття, опублікована у квітні 1997
@uk
مقالة علمية (نشرت في أبريل 1997)
@ar
name
Characterization of bovine end ...... d role of haem in dimerization
@ast
Characterization of bovine end ...... d role of haem in dimerization
@en
Characterization of bovine end ...... d role of haem in dimerization
@nl
type
label
Characterization of bovine end ...... d role of haem in dimerization
@ast
Characterization of bovine end ...... d role of haem in dimerization
@en
Characterization of bovine end ...... d role of haem in dimerization
@nl
prefLabel
Characterization of bovine end ...... d role of haem in dimerization
@ast
Characterization of bovine end ...... d role of haem in dimerization
@en
Characterization of bovine end ...... d role of haem in dimerization
@nl
P2093
P2860
P356
P1433
P1476
Characterization of bovine end ...... d role of haem in dimerization
@en
P2093
W R Kukovetz
P2860
P304
P356
10.1042/BJ3230159
P407
P478
323 ( Pt 1)
P577
1997-04-01T00:00:00Z