Metabolism of carcinogenic heterocyclic and aromatic amines by recombinant human cytochrome P450 enzymes
about
Regulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagusDNA Sequence Modulates the Conformation of the Food Mutagen 2-Amino-3-methylimidazo[4,5- f ]quinoline in the Recognition Sequence of the Nar I Restriction Enzyme † , ‡Human Cytochrome P450 1A1 Structure and Utility in Understanding Drug and Xenobiotic MetabolismBase-displaced intercalation of the 2-amino-3-methylimidazo[4,5-f]quinolone N2-dG adduct in the NarI DNA recognition sequenceMetabolism and biomarkers of heterocyclic aromatic amines in molecular epidemiology studies: lessons learned from aromatic aminesMouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)Contributions of human enzymes in carcinogen metabolismPreferred binding orientations of phenacetin in CYP1A1 and CYP1A2 are associated with isoform-selective metabolism.Summary of information on human CYP enzymes: human P450 metabolism data.Base-displaced intercalated structure of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in the recognition sequence of the NarI restriction enzyme, a hotspot for -2 bp deletions.Dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced prostate carcinogenesis in CYP1A-humanized miceRapid induction of colon carcinogenesis in CYP1A-humanized mice by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate.N-oxidation of aromatic amines by intracellular oxidases.A comprehensive approach to the profiling of the cooked meat carcinogens 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, and their metabolites in human urine.Genetic polymorphism of CYP1A2 increases the risk of myocardial infarction.Biomonitoring of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and its carcinogenic metabolites in urine.Heterocyclic amines: Mutagens/carcinogens produced during cooking of meat and fish.Base-Displaced Intercalated Conformation of the 2-Amino-3-methylimidazo[4,5-f]quinoline N(2)-dG DNA Adduct Positioned at the Nonreiterated G(1) in the NarI Restriction Site.Cytochrome P450-mediated metabolism and DNA binding of 2-amino-1,7-dimethylimidazo[4,5-g]quinoxaline and its carcinogenic isomer 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in mice.Applications of CYP-450 expression for biomonitoring in environmental healthRed meat intake, doneness, polymorphisms in genes that encode carcinogen-metabolizing enzymes, and colorectal cancer riskUnderstanding the gender disparity in bladder cancer risk: the impact of sex hormones and liver on bladder susceptibility to carcinogens.Role of human CYP1A1 and NAT2 in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced mutagenicity and DNA adducts.Chemistry and structural biology of DNA damage and biological consequencesRole of human sulfotransferase 1A1 and N-acetyltransferase 2 in the metabolic activation of 16 heterocyclic amines and related heterocyclics to genotoxicants in recombinant V79 cells.Mechanisms of DNA damage, repair, and mutagenesis.Reduction of aromatic and heterocyclic aromatic N-hydroxylamines by human cytochrome P450 2S1.N-Acetyltransferase 2 polymorphisms, cigarette smoking and alcohol consumption, and oral squamous cell cancer risk.Effects of chemoprotective agents on the metabolic activation of the carcinogenic arylamines PhIP and 4-aminobiphenyl in human and rat liver microsomes.4-aminobiphenyl-induced liver and urinary bladder DNA adduct formation in Cyp1a2(-/-) and Cyp1a2(+/+) mice.Human T lymphocytes bioactivate heterocyclic aromatic amines by forming DNA adducts.N-hydroxylation of 4-aminobiphenylHomology modelling of human CYP1A2 based on the CYP2C5 crystallographic template structure.
P2860
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P2860
Metabolism of carcinogenic heterocyclic and aromatic amines by recombinant human cytochrome P450 enzymes
description
1997 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1997
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im April 1997 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 1997/04/01)
@sk
vědecký článek publikovaný v roce 1997
@cs
wetenschappelijk artikel (gepubliceerd op 1997/04/01)
@nl
наукова стаття, опублікована у квітні 1997
@uk
مقالة علمية (نشرت في أبريل 1997)
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name
Metabolism of carcinogenic het ...... human cytochrome P450 enzymes
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Metabolism of carcinogenic het ...... human cytochrome P450 enzymes
@en
Metabolism of carcinogenic het ...... human cytochrome P450 enzymes
@nl
type
label
Metabolism of carcinogenic het ...... human cytochrome P450 enzymes
@ast
Metabolism of carcinogenic het ...... human cytochrome P450 enzymes
@en
Metabolism of carcinogenic het ...... human cytochrome P450 enzymes
@nl
prefLabel
Metabolism of carcinogenic het ...... human cytochrome P450 enzymes
@ast
Metabolism of carcinogenic het ...... human cytochrome P450 enzymes
@en
Metabolism of carcinogenic het ...... human cytochrome P450 enzymes
@nl
P2093
P356
P1433
P1476
Metabolism of carcinogenic het ...... human cytochrome P450 enzymes
@en
P2093
F. F. Kadlubar
F. P. Guengerich
G. J. Hammons
R. H. Tukey
P304
P356
10.1093/CARCIN/18.4.851
P407
P577
1997-04-01T00:00:00Z